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Journal Article
Journal Article
Trends in Cell Biology, ISSN 0962-8924, 01/2018, Volume 28, Issue 1, pp. 1 - 3
The biological diversity of ubiquitination resides in the multivalent nature of linkage-specific homotypic and heterotypic ubiquitin (Ub) chains. A recent... 
Huntingtin (HTT) | K11/K48 branched | APC/C | ubiquitin | heterotypic Ub chain | Ubiquitin | Physiological aspects | Biological diversity
Journal Article
Trends in Cell Biology, ISSN 0962-8924, 09/2019, Volume 29, Issue 9, pp. 704 - 716
Ubiquitin chains of distinct topologies control the stability, interactions, or localization of many proteins in eukaryotic cells, and thus play an essential... 
protein quality control | ubiquitin code | ubiquitin | branched ubiquitin chain | ANAPHASE-PROMOTING COMPLEX | ACTIVATION | MULTIUBIQUITIN CHAIN | MECHANISM | SPECIFICITY | RECOGNITION | DEGRADATION | POLYUBIQUITIN CHAIN | BINDING | REVEALS | CELL BIOLOGY | Ubiquitin | Cells | Signaling | Information transfer | Chain branching | Control stability | Topology | Localization
Journal Article
Analytical Chemistry (Washington), ISSN 0003-2700, 04/2017, Volume 89, Issue 8, pp. 4428 - 4428
Ubiquitin (Ub) has a broad functional range that has been ascribed to the formation of an array of polymeric ubiquitin chains. Understanding the precise roles... 
Enrichment | Binding | Chain branching | Chains | Tubes | Chains (polymeric) | Inhibition | Mass spectrometry
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 10/2017, Volume 56, Issue 43, pp. 13333 - 13337
Chemical ubiquitination is an effective approach for accessing structurally defined, atypical ubiquitin (Ub) chains that are difficult to prepare by other... 
protein chemical synthesis | native chemical ligation | post-translational modifications | proteolysis | ubiquitin | LIGATION | DEUBIQUITINASES | PEPTIDE HYDRAZIDES | DIUBIQUITIN | CHEMISTRY, MULTIDISCIPLINARY | CODE | PROTEIN-DEGRADATION | COMPLEXITY | UBIQUITYLATION | POLYUBIQUITIN CHAINS | LINKAGE | Ubiquitin | Usage | Chemical synthesis | Proteolysis | Chain branching | Chains | Ubiquitination
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2018, Volume 115, Issue 7, p. E1401
Different polyubiquitin chain linkages direct substrates toward distinct cellular pathways. K63-linked ubiquitylation is known to regulate... 
Ubiquitin | Linkages | Chain branching | Chains | Seeding | Cells | Substrates | Proteins | Degradation | Signal transduction | Cell fate | Proteasomes | Transduction | Apoptosis | Quantitative analysis
Journal Article
Chinese Chemical Letters, ISSN 1001-8417, 07/2018, Volume 29, Issue 7, pp. 1155 - 1159
The affinities of chemically synthetic linkage- and length-defined K -branched ubiquitin chains binding to ubiquitin receptor S5a were quantitatively measured.... 
Post-translational modification | Affinity | Ubiquitination | K11,48-branched chains | Native chemical ligation of peptide hydrazine | Deubiquitination | branched chains
Journal Article
Structure (London, England : 1993), ISSN 0969-2126, 01/2020, Volume 28, Issue 1, pp. 29 - 29
Post-translational substrate modification with ubiquitin is essential for eukaryotic cellular signaling. Polymeric ubiquitin chains are assembled with specific... 
PROTEIN DOCKING | SPECIFICITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | VALIDATION | CONFORMATION | DI-UBIQUITIN | CELL BIOLOGY | UBA DOMAIN | BIOPHYSICS | UBIQUITYLATION | DEGRADATION | POLYUBIQUITIN CHAINS | LINKAGE
Journal Article
Structure, ISSN 0969-2126, 05/2013, Volume 21, Issue 5, pp. 727 - 740
Research on ubiquitin (Ub) signaling has focused primarily on homogeneously linked polyUb. Although polyUb containing different linkages within the same chain... 
Linkages | Receptors | Messages | Lysine | Branched | Trimers | Polymers | Recognition
Journal Article
Annual Review of Cell and Developmental Biology, ISSN 1081-0706, 10/2018, Volume 34, Issue 1, pp. 137 - 162
Journal Article
Angewandte Chemie, ISSN 0044-8249, 10/2017, Volume 129, Issue 43, p. 13518
Chemical ubiquitination is an effective approach for accessing structurally defined, atypical ubiquitin (Ub) chains that are difficult to prepare by other... 
Ubiquitin | Ubiquitination | Chain branching | Chains | Chemical synthesis
Journal Article