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Annales Pharmaceutiques Francaises, ISSN 0003-4509, 07/2019, Volume 77, Issue 4, pp. 302 - 312
Timolol is a non-cardioselective beta blocker and has different combined ophthalmic dosage forms for treatment of glaucoma. This research introduce an HPLC... 
Brimonidine | HPLC | Timolol | Dorzolamide | Brinzolamide
Journal Article
Structure, ISSN 0969-2126, 03/2018, Volume 26, Issue 3, pp. 383 - 390.e3
Human carbonic anhydrases (hCAs) play various roles in cells, and have been drug targets for decades. Sequence similarities of hCA isoforms necessitate... 
dorzolamide | hydrogen bonding | drug binding | brinzolamide | ethoxzolamide | perdeuteration | MD simulations | human carbonic anhydrase | neutron crystallography
Journal Article
Analytical Chemistry Letters, ISSN 2229-7928, 11/2017, Volume 7, Issue 6, pp. 805 - 812
Sensitive, simple and accurate thin-layer chromatography (TLC) - densitometry method for simultaneous determination of brinzolamide (BRZ) and timolol maleate... 
TLC | Chromatographic separation | brinzolamide | timolol maleate
Journal Article
Ophthalmology, ISSN 0161-6420, 2018, Volume 126, Issue 8, pp. 1095 - 1104
Purpose: To determine the intraocular pressure (IOP)-lowering effect of fixed-combination brinzolamide 1%/brimonidine 0.2% (BBFC) over a 24-hour period.... 
PRIMARY OPEN-ANGLE | OCULAR-HYPERTENSION-TREATMENT | EFFICACY | PATTERN | BRIMONIDINE | OPHTHALMOLOGY | PERFUSION-PRESSURE | GLAUCOMA | TIMOLOL | PROGRESSION | ONSET | Brimonidine | Dosage and administration | Drug therapy, Combination | Analysis | Brinzolamide
Journal Article
Archivos de la Sociedad Espanola de Oftalmologia, ISSN 0365-6691, 12/2017, Volume 92, Issue 12, pp. 571 - 576
Objective To evaluate the effect of treatment with topical brinzolamide on visual acuity and nystagmus intensity in patients with congenital nystagmus.... 
Topical carbonic anhydrase inhibitors | Video-oculography | Azopt | Nystagmus | Brinzolamide
Journal Article
Journal of Glaucoma, ISSN 1057-0829, 11/2018, Volume 27, Issue 11, pp. e183 - e184
We report a case of a patient who developed a severe case of follicular conjunctivitis from brinzolamide after 1.5 years of consistent use. This patient was... 
drop allergies | brimonidine | brinzolamide | glaucoma | follicular conjunctivitis | OCULAR HYPERTENSION | OPHTHALMOLOGY | Case studies | Care and treatment | Usage | Conjunctivitis | Brinzolamide
Journal Article
Indian Journal of Ophthalmology, ISSN 0301-4738, 02/2016, Volume 64, Issue 2, pp. 127 - 131
Purpose: To compare the efficacy and tolerability of brinzolamide/timolol (BT) and dorzolamide/timolol (DT) fixed combinations on intraocular pressure (IOP)... 
Dorzolamide/timolol | Brinzolamide/timolol | Fixed combinations | TRIAL | SUSPENSION | OPEN-ANGLE GLAUCOMA | EFFICACY | SAFETY | 2-PERCENT/TIMOLOL 0.5-PERCENT | fixed combinations | OCULAR HYPERTENSION | OPHTHALMOLOGY | dorzolamide/timolol | TIMOLOL | Thiophenes - therapeutic use | Intraocular Pressure - drug effects | Prospective Studies | Thiazines - therapeutic use | Thiophenes - adverse effects | Humans | Middle Aged | Thiazines - adverse effects | Egypt | Male | Ophthalmic Solutions | Tonometry, Ocular | Adult | Female | Carbonic Anhydrase Inhibitors - adverse effects | Timolol - therapeutic use | Carbonic Anhydrase Inhibitors - therapeutic use | Timolol - adverse effects | Hospitals, University | Low Tension Glaucoma - drug therapy | Antihypertensive Agents - therapeutic use | Antihypertensive Agents - adverse effects | Glaucoma, Open-Angle - drug therapy | Sulfonamides - therapeutic use | Adolescent | Sulfonamides - adverse effects | Aged | Administration, Topical | Drug Combinations | Glaucoma | Care and treatment | Analysis | Dorzolamide | Dosage and administration | Comparative analysis | Brinzolamide | Intraocular pressure | Drugs | Studies | Diabetic retinopathy | Pain | Compliance | Diabetes | Index Medicus | timolol | dorzolamide | Original | Brinzolamide/timolol, dorzolamide/timolol, fixed combinations
Journal Article
Klinische Monatsblatter fur Augenheilkunde, ISSN 0023-2165, 2013, Volume 230, Issue 2, pp. 146 - 149
Journal Article
Frontiers in Pharmacology, ISSN 1663-9812, 02/2018, Volume 9, pp. 91 - 91
Novel ocular drug delivery systems (NODDSs) remain to be explored to overcome the anatomical and physiological barriers of the eyes. This study was to... 
Nanoliposomes | Cyclodextrin | Ocular drug delivery | Inclusion complex | Brinzolamide | Intraocular pressure | inclusion complex | brinzolamide | intraocular pressure | EFFICACY | VIVO | cyclodextrin | ocular drug delivery | PENETRATION | RELEASE | CARRIER | BIOAVAILABILITY | nanoliposomes | IN-VITRO | OPHTHALMIC DELIVERY | FORMULATIONS | PHARMACOLOGY & PHARMACY | LIPOSOMES
Journal Article
Pharmaceutical Development and Technology, ISSN 1083-7450, 05/2019, Volume 24, Issue 5, pp. 600 - 606
The aim of this study was to investigate the corneal penetration of brinzolamide (BZ) nanoemulsions (NEs) and evaluate their in vitro and ex vivo irritancy... 
nanoemulsions | transcorneal permeation | ocular irritancy test | glaucoma | Brinzolamide | cell viability assay | PERMEABILITY | MICROEMULSIONS | SURFACTANTS | OPACITY | TOXICITY | DELIVERY | OPEN-ANGLE GLAUCOMA | PENETRATION ENHANCERS | PHARMACOLOGY & PHARMACY | DORZOLAMIDE | EMULSIONS
Journal Article
Cutaneous and Ocular Toxicology, ISSN 1556-9527, 04/2019, Volume 38, Issue 2, pp. 196 - 200
Purpose: To investigate the acute effects of brinzolamide, betaxolol, and latanoprost (drugs commonly used in the medical management of glaucoma) on choroidal... 
choroid | latanoprost | betaxolol | thickness | Brinzolamide | 0.5-PERCENT | RISK | INTRAOCULAR-PRESSURE | TIMOLOL | PATHOGENESIS | PHARMACOKINETICS | OPHTHALMOLOGY | TOXICOLOGY | DORZOLAMIDE | PROGRESSION | OCULAR BLOOD-FLOW
Journal Article
Journal of Ocular Pharmacology and Therapeutics, ISSN 1080-7683, 04/2018, Volume 34, Issue 3, pp. 274 - 279
To evaluate efficacy and safety of brinzolamide (1%)/brimonidine (0.2%) fixed combination (BBFC) in normal tension glaucoma (NTG). This retrospective study... 
simbrinza | normal tension | brimonidine | fixed combination | brinzolamide | glaucoma | 0.5-PERCENT | RANDOMIZED-TRIAL | INTRAOCULAR-PRESSURE | OPEN-ANGLE GLAUCOMA | REDUCTION | OPHTHALMOLOGY | PHARMACOLOGY & PHARMACY | PROGRESSION
Journal Article
Indian Journal of Pharmaceutical Sciences, ISSN 0250-474X, 09/2016, Volume 78, Issue 5, pp. 631 - 640
A high performance liquid chromatographic method was developed and validated for the quantitative determination of brinzolamide and brimonidinetartrate.... 
Brimonidine tartrate | Validation | Robustness | Fractional factorial design | High performance liquid chromatography | Brinzolamide | high performance liquid chromatography | brimonidine tartrate | robustness | PHARMACOLOGY & PHARMACY | OPTIMIZATION | validation | fractional factorial design | HPLC
Journal Article
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 12/2018, Volume 553, Issue 1-2, pp. 21 - 28
Journal Article
INDIAN JOURNAL OF OPHTHALMOLOGY, ISSN 0301-4738, 07/2019, Volume 67, Issue 7, pp. 1202 - 1202
Hypertriglyseridemia is a metabolic disorder that can cause vascular dysfucntion and be causally associated with glaucoma. Herein we present the case of a... 
juvenile open angle glaucoma | OPHTHALMOLOGY | PREVALENCE | Hypertriglyceridemia | primary open angle glaucoma | Glaucoma | Hyperlipidemia | Risk factors | Brinzolamide | Bimatoprost | Case studies | Complications and side effects | Open-angle glaucoma | Optic nerve | Consent | Triglycerides | Metabolism | Patients | Case Reports
Journal Article
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