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Journal Article
Journal Article
Annual review of immunology, ISSN 0732-0582, 4/2020, Volume 38, Issue 1, pp. 673 - 703
Journal Article
Journal of molecular biology, ISSN 0022-2836, 05/2019, Volume 431, Issue 12, pp. 2223 - 2247
human immunodeficiency virus | glycosylation | antibodies | structure | vaccinology | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Epitopes - immunology | HIV Infections - immunology | HIV Infections - prevention & control | Antibodies, Neutralizing - immunology | HIV-1 - immunology | Molecular Mimicry | env Gene Products, Human Immunodeficiency Virus - immunology | Humans | AIDS Vaccines - immunology | Models, Molecular | AIDS Vaccines - therapeutic use | Polysaccharides - immunology | AIDS vaccines | HIV (Viruses) | Health aspects | Antigenic determinants | Index Medicus | Env, envelope spike | CHO, Chinese hamster ovary | UFO, uncleaved prefusion-optimized | BCR, B cell receptor | EM, electron microscopy | MPER, membrane proximal external region | HIV-1, human immunodeficiency virus type 1 | 2, heptad repeat 1 or 2 | Glc, glucose | bnAb(s), broadly neutralizing antibody(ies) | HCDR3, third heavy-chain complementarity-determining regions | NFL, native flexibly linked | GlcNAc, N-acetylglucosamine | CT, cytoplasmic tail | PNGS, potential N-glycosylation sites | Neu5Ac, N-acetylneuraminic acid (sialic acid) | nAb(s), neutralizing antibody(ies) | CDR, complementarity-determining regions | α-man I and II, α-mannosidase I and II | gl-bnAb(s), germline-bnAb(s) | TAMP, trimer-associated mannose patch | HEK, human embryonic kidney | LOS, lipooligosaccharides | GnT I, N-acetylglucosaminyltransferase I | AIDS, acquired immune deficiency syndrome | CD4bs, CD4 binding site | Gal, galactose | PBMC, peripheral blood mononuclear cell | CCR5, C-C chemokine receptor type 5 | TM, transmembrane region | SP, signal peptide | Man, mannose | founder | HR1 | KDO, 2-keto-3-deoxy-D-manno-octulosonic acid | SC, single-chain | Fuc, fucose | PNS, peripheral nervous system | CXCR4, C-X-C chemokine receptor type 4 | TF, transmitted | GlcN, glucosamine | cGMP, current good manufacturing practices | ER, endoplasmic reticulum | IMP, intrinsic mannose patch
Journal Article