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Journal of Biological Chemistry, ISSN 0021-9258, 12/2014, Volume 289, Issue 49, pp. 34129 - 34140
.... Results: Obesity and chronic exercise antagonistically regulate thermogenic capacity of BAT and subcutaneous white fat (SC WAT). Conclusion... 
Obesity | ADIPOCYTES | MESSENGER-RNA EXPRESSION | EXHAUSTIVE EXERCISE | ATGL | BIOCHEMISTRY & MOLECULAR BIOLOGY | AMP-activated Kinase (AMPK) | Peroxisome Proliferator-activated Receptor Coactivator 1-(PGC-1a) (PPARGC1A) | UCP-1 | Brown Adipocytes | FNDC5 | Adipose Tissue Metabolism | Irisin | SKELETAL-MUSCLE | Exercise | COLD-EXPOSURE | GENE-EXPRESSION | NERVOUS-SYSTEM ACTIVITY | ADIPOSE-TISSUE | Thermogenesis - genetics | Rats, Wistar | Ion Channels - genetics | Male | Muscle, Skeletal - metabolism | Mitochondrial Proteins - genetics | Physical Endurance | Obesity - genetics | Mitochondrial Proteins - metabolism | Diet, High-Fat | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Obesity - etiology | Energy Metabolism - genetics | Physical Conditioning, Animal | Dietary Fats - adverse effects | Signal Transduction | Gene Expression Regulation | Rats | Transcription Factors - genetics | Organ Specificity | Fibronectins - metabolism | Obesity - metabolism | Obesity - pathology | Transcription Factors - metabolism | Animals | Ion Channels - metabolism | Adipose Tissue, Brown - metabolism | Fibronectins - genetics | Uncoupling Protein 1 | Subcutaneous Fat, Abdominal - metabolism | UCP-1, FNDC5, Irisin, Brown Adipocytes, ATGL | Peroxisome Proliferator-activated Receptor γ Coactivator 1-α (PGC-1a) (PPARGC1A) | Metabolism
Journal Article
Journal Article
Journal Article
Journal Article
Nature (London), ISSN 1476-4687, 2012, Volume 481, Issue 7382, pp. 463 - 468
.... Irisin acts on white adipose cells in culture and in vivo to stimulate UCP1 expression and a broad program of brown-fat-like development... 
SKELETAL-MUSCLE | COACTIVATOR | PHOSPHORYLATION | ROLES | PGC-1-ALPHA | MULTIDISCIPLINARY SCIENCES | SWITCH | MYOBLAST | EXPRESSION | EXERCISE | PROTECTS | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Adipocytes - drug effects | Obesity - blood | Adipose Tissue, White - cytology | Mitochondrial Proteins - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Models, Animal | Energy Metabolism - physiology | Intracellular Signaling Peptides and Proteins - genetics | Obesity - chemically induced | Mice, Transgenic | Trans-Activators - deficiency | Obesity - prevention & control | Plasma - chemistry | Adipose Tissue, Brown - drug effects | Exercise - physiology | Mice | Mice, Inbred BALB C | Transcription Factors | Energy Metabolism - drug effects | Thermogenesis - genetics | Adipose Tissue, White - metabolism | Adipocytes - cytology | Culture Media, Conditioned - pharmacology | Subcutaneous Fat - metabolism | Insulin Resistance - physiology | Cell Respiration - drug effects | Subcutaneous Fat - drug effects | Trans-Activators - genetics | Energy Metabolism - genetics | Gene Expression Regulation - genetics | Cells, Cultured | Hormones - secretion | Muscle Cells - metabolism | Physical Conditioning, Animal - physiology | Subcutaneous Fat - cytology | Gene Expression Regulation - drug effects | Adipose Tissue, Brown - cytology | Animals | Hormones - metabolism | Ion Channels - metabolism | Adipocytes - metabolism | Trans-Activators - secretion | Trans-Activators - metabolism | Adipose Tissue, Brown - metabolism | Thermogenesis - drug effects | Uncoupling Protein 1 | Adipose Tissue, White - drug effects
Journal Article
Nature reviews. Molecular cell biology, ISSN 1471-0080, 2016, Volume 17, Issue 11, pp. 691 - 702
Journal Article
Cell metabolism, ISSN 1550-4131, 2012, Volume 15, Issue 6, pp. 838 - 847
Journal Article