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The Journal of Infectious Diseases, ISSN 0022-1899, 10/2013, Volume 208, Issue 8, pp. 1342 - 1348
Journal Article
Experimental Parasitology, ISSN 0014-4894, 09/2017, Volume 180, pp. 71 - 83
Journal Article
Journal of Infectious Diseases, ISSN 0022-1899, 12/2016, Volume 214, Issue 12, pp. 1856 - 1864
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 07/2018, Volume 62, Issue 7
Recent reports highlighting the global significance of cryptosporidiosis among children have renewed efforts to develop control measures. We evaluated the... 
Cryptosporidium hominis | BKI 1369 | Bumped kinase inhibitor | Gnotobiotic pigs | SYSTEM | gnotobiotic pigs | CDPK1 | C. PARVUM | MICROBIOLOGY | bumped kinase inhibitor | CHILDREN | POTENT | T. GONDII | COMMUNITY | SELECTIVE INHIBITORS | PHARMACOLOGY & PHARMACY | BURDEN | DEVELOPING-COUNTRIES
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 06/2018, Volume 62, Issue 6, pp. e00051 - e00118
In Toxoplasma gondii, calcium-dependent protein kinase 1 (CDPK1) is an essential protein kinase required for invasion of host cells. We have developed several... 
Inhibitor | Cellular thermal shift assay | Toxoplasma gondii | Bumped kinase inhibitor | Protein kinase | TARGET | CELLS | PARASITES | ACTIVATION | CDPK1 | C. PARVUM | MICROBIOLOGY | bumped kinase inhibitor | protein kinase | POTENT | T. GONDII | inhibitor | SELECTIVE INHIBITORS | PHARMACOLOGY & PHARMACY | INFECTION | cellular thermal shift assay
Journal Article
International Journal for Parasitology, ISSN 0020-7519, 10/2017, Volume 47, Issue 12, pp. 811 - 821
[Display omitted] •The Besnoitia besnoiti CDPK1 orthologue was identified and cloned.•Activity of recombinant BbCDPK1 was greatly inhibited by a panel of... 
In vitro assay | Chemotherapy | Besnoitia besnoiti | Bumped kinase inhibitors | CDPK1 | DEPENDENT PROTEIN-KINASES | SELECTIVE INHIBITORS | BOVINE BESNOITIOSIS | TOXOPLASMA-GONDII | MALARIA | TARGETS | INFECTION | PARASITOLOGY | Protein kinases | Cancer | Index Medicus
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 04/2017, Volume 61, Issue 4
We present the effects of two novel bumped kinase inhibitors, BKI-1517 and BKI-1553, against Neospora caninum tachyzoites in vitro and in experimentally... 
Apicomplexan parasites | Calcium-dependent protein kinase | Chemotherapy | Fertility | Neospora caninum | Vertical transmission | Bumped kinase inhibitor | Pregnant mouse model | ANTIBODIES | pregnant mouse model | CDPK1 | fertility | CATTLE | VACCINATION | MICROBIOLOGY | calcium-dependent protein kinase | chemotherapy | bumped kinase inhibitor | ISOLATE | PREGNANCY | IN-VITRO | POTENT | vertical transmission | SELECTIVE INHIBITORS | TOXOPLASMA-GONDII | PHARMACOLOGY & PHARMACY | apicomplexan parasites | Protein Kinases - metabolism | Oxazines | Protein Kinases - genetics | Protozoan Proteins - antagonists & inhibitors | Humans | Neospora - enzymology | Coccidiosis - drug therapy | Neospora - genetics | Protozoan Proteins - genetics | Pyrimidines - chemistry | Quinolines - pharmacology | Protein Kinase Inhibitors - chemistry | Pyrazoles - chemistry | Protozoan Proteins - metabolism | Fibroblasts - parasitology | beta-Galactosidase - metabolism | Fertility - drug effects | Female | Coccidiosis - parasitology | Genes, Reporter | Brain - parasitology | Life Cycle Stages - drug effects | Life Cycle Stages - physiology | Pyrazoles - pharmacology | Gene Expression | Quinolines - chemistry | Pyrimidines - pharmacology | Coccidiostats - chemistry | Brain - drug effects | Pregnancy | Xanthenes | Neospora - growth & development | Animals | Coccidiosis - transmission | Fibroblasts - drug effects | Cell Proliferation - drug effects | Coccidiostats - pharmacology | Mice | Mice, Inbred BALB C | Protein Kinase Inhibitors - pharmacology | Primary Cell Culture | beta-Galactosidase - genetics | Neospora - drug effects | Infectious Disease Transmission, Vertical - prevention & control
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 1/2014, Volume 209, Issue 2, pp. 275 - 284
Journal Article
Parasitology, ISSN 0031-1820, 2014, Volume 141, Issue 11, pp. 1499 - 1509
Journal Article