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Chemistry – A European Journal, ISSN 0947-6539, 04/2019, Volume 25, Issue 21, p. n/a
Despite extensive quantities of work with regard to reactivation of organophosphorus‐inhibited and aged acetylcholinesterase (AChE) and butyrylcholinesterase... 
acetylcholinesterase | reactivation | butyrylcholinesterase | organophosphorus | resurrection | Cholinergics | Oximes | Activation | Acetylcholinesterase
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 03/2013, Volume 203, Issue 1, pp. 77 - 80
Journal Article
Toxicology, ISSN 0300-483X, 08/2018, Volume 406-407, pp. 104 - 113
The antidotal property of oximes is attributed to their ability to reactivate acetylcholinesterase (AChE) inhibited by organophosphorus compounds (OP) such as... 
Antidotes | HI-6 | K-oximes | Nerve agents | Cholinesterase | 2-PAM | PYRIDINIUM OXIMES | CHOLINESTERASE REACTIVATORS | CRYSTAL-STRUCTURES | HUMAN BUTYRYLCHOLINESTERASE | IN-VITRO | BRAIN-BARRIER PENETRATION | KINETIC-ANALYSIS | PHARMACOLOGY & PHARMACY | TOXICOLOGY | ORGANOPHOSPHORUS COMPOUNDS | ALDOXIMES | Nitriles | Organophosphorus compounds | Genetic aspects | Index Medicus
Journal Article
Analytical Chemistry, ISSN 0003-2700, 10/2013, Volume 85, Issue 20, pp. 9686 - 9691
Considering inter- or intra-individual variation in the normal levels of acetylcholinesterase (AChE), real-time measurement of AChE via the reactivation from a... 
NERVE AGENTS | BUTYRYLCHOLINESTERASE | CHEMISTRY, ANALYTICAL | ASSAY | ENZYME-ACTIVITY | PHOSPHORYLATED ACETYLCHOLINESTERASE | QUANTIFICATION | IMMUNOSENSOR | THIOCHOLINE | MASS-SPECTROMETRY | PESTICIDES | Acetylcholinesterase | Cholinesterases | Research | Measurement | Enzymes | Nanocomposites | Pesticides | Erythrocytes | Biomarkers | Desorption | Enrichment | Symbols | Activation | Exposure | Inhibition | Adducts
Journal Article
Archives of Toxicology, ISSN 0340-5761, 8/2017, Volume 91, Issue 8, pp. 2837 - 2847
The freshwater planarian Dugesia japonica has recently emerged as an animal model for developmental neurotoxicology and found to be sensitive to... 
Biomedicine, general | Environmental Health | Biomedicine | Occupational Medicine/Industrial Medicine | Planarians | Organophosphorus pesticides | Pharmacology/Toxicology | Acetylcholinesterase kinetics and inhibition | Fluoride and oxime reactivation | MOLECULAR CHARACTERIZATION | BUTYRYLCHOLINESTERASE | TORPEDO-CALIFORNICA | MODEL SYSTEM | SPECIFICITY | ACETYLCHOLINESTERASE GENES | NEMATODE CAENORHABDITIS-ELEGANS | PHOSPHYLATED CHOLINESTERASES | ACTING OXIME REACTIVATORS | TOKYO SUBWAY | TOXICOLOGY | Species Specificity | Cholinesterase Reactivators - pharmacology | Humans | Animals | Cholinesterase Inhibitors - pharmacology | Butyrylcholinesterase - metabolism | Pesticides - toxicity | Models, Animal | Cholinesterases - metabolism | Organophosphorus Compounds - toxicity | In Vitro Techniques | Acetylcholinesterase - metabolism | Enzymes | Enzyme inhibitors | Surface active agents | Pesticides | Carbamates | Fluorides | Catalysis | Separation | Toxicity | Staining | Nervous system | Activation | Acetylcholinesterase | Diazinon | Toxicology | Fluoride | Neostigmine | Esterase | Agrochemicals | Donepezil | Inhibition | Tacrine | Pesticide toxicity | Chlorpyrifos | Quaternary | Paraoxon | Physostigmine | Cholinesterase | Vertebrates | Inhibitors | Sodium | Carbaryl | Dichlorvos | Pyridostigmine | Cholinergic nerves | Sodium fluoride | In vitro methods and tests | Index Medicus | organophosphorus pesticides | acetylcholinesterase kinetics and inhibition | planarians | fluoride and oxime reactivation
Journal Article
Journal Article
Bioscience Reports, ISSN 0144-8463, 06/2018, Volume 38, Issue 3, p. BSR20180609
The role of water in oxime-mediated reactivation of phosphylated cholinesterases (ChEs) has been asked with recurrence. To investigate oximate water structure... 
SERIES | KINETICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | REACTIVITY | DYNAMICS | AUTOMATION | GENERAL FORCE-FIELD | HUMAN BUTYRYLCHOLINESTERASE | ALPHA-NUCLEOPHILES | RESIDUES | MOLECULES | CELL BIOLOGY | Oximes - chemistry | Phosphorylation | Humans | Water - chemistry | Acetylcholinesterase - chemistry | Kinetics | Molecular Dynamics Simulation | Index Medicus
Journal Article
Journal of Theoretical and Computational Chemistry, ISSN 0219-6336, 11/2015, Volume 14, Issue 7
Human butyrylcholinesterase (BChE) is a bioscavenger that protects the enzyme which is critical for the central nerve system, acetylcholinesterase, from... 
QM/MM | molecular modeling | mutants | Human butyrylcholinesterase | MOLECULAR-DYNAMICS | MYOSIN | HYDROLYSIS | CHEMISTRY, MULTIDISCIPLINARY | ANHYDRIDE HYDROLASE ACTIVITY | ACETYLCHOLINESTERASE | PARAMETERIZATION | SIMULATIONS | CHOLINESTERASES | RESIDUES | INSIGHTS | Human | Hydrolysis | Residues | Enzymes | Activation | Transformations | Catalysis | Proposals
Journal Article
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, ISSN 0103-5053, 05/2019, Volume 30, Issue 5, pp. 1095 - 1102
The use of nerve agents, organophosphorus compounds which irreversibly inhibit acetylcholinesterase, in conflicts and terrorism has gained renewed geopolitical... 
BUTYRYLCHOLINESTERASE | nerve agents' surrogates | ASSAY | MANAGEMENT | drug screening | COMPLEXES | acetylcholinesterase | CRYSTAL-STRUCTURES | Ellman's test | INDOXYLACETATE | CHEMISTRY, MULTIDISCIPLINARY | IN-VITRO | OXIMES | STRUCTURAL REQUIREMENTS | ORGANOPHOSPHORUS COMPOUNDS
Journal Article