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Nature Reviews Drug Discovery, ISSN 1474-1776, 2012, Volume 11, Issue 1, pp. 25 - 36
Interfacial inhibitors belong to a broad class of natural products and synthetic drugs that are commonly used to treat cancers as well as bacterial and HIV... 
HUMAN CALCINEURIN | COVALENT COMPLEX | ALLOSTERIC PROTEINS | DNA TOPOISOMERASE-II | STRUCTURAL BASIS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CRYSTAL-STRUCTURE | BREAKAGE-REUNION REACTION | PHARMACOLOGY & PHARMACY | X-RAY STRUCTURES | ANTITUMOR DRUGS | INTEGRASE INHIBITORS | Antibiotics | Etoposide | Research | Diagnosis | Drug therapy | Health aspects | HIV infection
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 12/2007, Volume 357, Issue 25, pp. 2562 - 2575
This study examines the toxicity of immunosuppressive regimens in renal-transplant recipients. A regimen containing mycophenolate mofetil, daclizumab, low-dose... 
MULTICENTER TRIAL | MEDICINE, GENERAL & INTERNAL | CYCLOSPORINE MICROEMULSION | EFFICACY | KIDNEY-TRANSPLANTATION | IMMUNOSUPPRESSION | ALLOGRAFT RECIPIENTS | TACROLIMUS | MYCOPHENOLATE-MOFETIL | SIROLIMUS | NEPHROTOXICITY | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Adrenal Cortex Hormones - therapeutic use | Enzyme Inhibitors - administration & dosage | Antibodies, Monoclonal, Humanized | Calcineurin Inhibitors | Treatment Failure | Adult | Diabetes Mellitus - etiology | Female | Drug Therapy, Combination | Mycophenolic Acid - administration & dosage | Immunosuppressive Agents - administration & dosage | Sirolimus - adverse effects | Tacrolimus - administration & dosage | Prednisone - administration & dosage | Glomerular Filtration Rate | Graft Rejection - prevention & control | Kaplan-Meier Estimate | Kidney Transplantation | Immunoglobulin G - administration & dosage | Opportunistic Infections | Sirolimus - administration & dosage | Mycophenolic Acid - analogs & derivatives | Antibodies, Monoclonal - administration & dosage | Cyclosporine - administration & dosage | Immunosuppressive Agents - adverse effects | Aged | Adrenal Cortex Hormones - administration & dosage | Transplantation | Corticosteroids | Kidneys | Research | Health aspects | Immunosuppressive agents | Medical research | Immunology | Inhibitor drugs | Transplants & implants | Toxicity | Inhibidors enzimàtics | Posologia | Ús terapèutic | Corticosteroides | Rebuig (Biologia) | Posology | Therapeutic use | Immunosupressive agents | Graft rejection | Trasplantament renal | Enzyme inhibitors | Adrenocortical hormones | Immunosupressors | Kidney transplantation | Tacrolimus: administration & dosage | Medical and Health Sciences | Graft Rejection: prevention & control | Immunoglobulin G: administration & dosage | Medicin och hälsovetenskap | Mycophenolic Acid: administration & dosage | Antibodies | Klinisk medicin | Monoclonal: administration & dosage | Prednisone: administration & dosage | Adrenal Cortex Hormones: administration & dosage | Immunosuppressive Agents: administration & dosage | Mycophenolic Acid: analogs & derivatives | Sirolimus: administration & dosage | Cyclosporine: administration & dosage | Calcineurin: antagonists & inhibitors | Diabetes Mellitus: etiology | Urologi och njurmedicin | Sirolimus: adverse effects | Adrenal Cortex Hormones: therapeutic use | Enzyme Inhibitors: administration & dosage | Immunosuppressive Agents: adverse effects | Clinical Medicine | Immunosuppressive Agents: therapeutic use | Urology and Nephrology
Journal Article
Transplantation, ISSN 0041-1337, 02/2018, Volume 102, Issue 2S Suppl 1, pp. S60 - S70
ABSTRACTMalignancy is the second most common single cause of death observed in organ transplant recipients. The excess cancer risk is related to intensity and... 
SOLID-ORGAN TRANSPLANTATION | SURGERY | RENAL-ALLOGRAFT RECIPIENTS | IMMUNOLOGY | TRANSPLANTATION | PHASE-II TRIAL | TUBEROUS SCLEROSIS COMPLEX | NONMELANOMA SKIN-CANCER | KAPOSIS-SARCOMA | POSTTRANSPLANT LYMPHOPROLIFERATIVE DISORDERS | KIDNEY-TRANSPLANTATION | SQUAMOUS-CELL CARCINOMA | ENDOTHELIAL GROWTH-FACTOR | TOR Serine-Threonine Kinases - metabolism | Tumor Virus Infections - virology | Humans | Immunosuppressive Agents - therapeutic use | Neoplasms - prevention & control | Protein Kinase Inhibitors - adverse effects | TOR Serine-Threonine Kinases - antagonists & inhibitors | Neoplasms - virology | Time Factors | Graft Rejection - mortality | Tumor Virus Infections - immunology | Anticarcinogenic Agents - adverse effects | Opportunistic Infections - immunology | Drug Therapy, Combination | Anticarcinogenic Agents - therapeutic use | Organ Transplantation - mortality | Graft Rejection - enzymology | Opportunistic Infections - virology | Graft Rejection - prevention & control | Risk Factors | Neoplasms - mortality | Treatment Outcome | Calcineurin Inhibitors - adverse effects | Animals | Signal Transduction - drug effects | Neoplasms - immunology | Protein Kinase Inhibitors - therapeutic use | Organ Transplantation - adverse effects | Immunosuppressive Agents - adverse effects | Graft Rejection - immunology | Immunocompromised Host | Graft Survival - drug effects | Prevention | Transplantation of organs, tissues, etc | Physiological aspects | Enzyme inhibitors | Carcinogenesis | Patient outcomes | Index Medicus
Journal Article