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Journal of General Physiology, ISSN 0022-1295, 12/2017, Volume 149, Issue 12, pp. 1065 - 1089
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 08/2009, Volume 123, Issue 2, pp. 151 - 177
The cardiac ryanodine receptor-Ca release channel (RyR2) is an essential sarcoplasmic reticulum (SR) transmembrane protein that plays a central role in... 
Heart failure | Cardiac arrhythmia | Catecholaminergic polymorphic ventricular tachycardia | Sudden cardiac death | Ryanodine receptor | POLYMORPHIC VENTRICULAR-TACHYCARDIA | BETA-ADRENERGIC STIMULATION | KDA FK506-BINDING PROTEIN | CA2+/CALMODULIN-DEPENDENT PROTEIN-KINASE | INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR | CALCIUM-RELEASE CHANNEL | SARCOPLASMIC-RETICULUM CA2 | AMINO-ACID-RESIDUES | PHARMACOLOGY & PHARMACY | CENTRAL CORE DISEASE | HEART-FAILURE PROGRESSION | Phosphorylation | Catecholamines - metabolism | Calcium - metabolism | Tachycardia, Ventricular - etiology | Ryanodine Receptor Calcium Release Channel - metabolism | Arrhythmias, Cardiac - etiology | Death, Sudden, Cardiac - etiology | Tachycardia, Ventricular - physiopathology | Animals | Sarcoplasmic Reticulum - genetics | Ryanodine Receptor Calcium Release Channel - genetics | Myocardium - metabolism | Sarcoplasmic Reticulum - metabolism | Mutation | Tachycardia | Phosphatases | Cardiac arrest | Calcium-binding proteins | Protein kinases | Natural pesticides | Adenosine triphosphatase | Protein binding | DAD, delayed after depolarisation | Associate editor | mAKAP, muscle specific A kinase anchoring protein | FKBP12 | 12.6, FK506 binding protein | Ca2+ exchange protein | type-2 | PP1, protein phosphatase 1 | SL, sarcolemma | HF, heart failure | PLB, phosphoplamban | CPVT, catecholaminergic polymorphic ventricular tachycardia | CM, calmodulin | calmodulim-dependent protein kinase II | ARVD2, arrhythmogenic right ventricular cardiomyopathy type 2 | RyR1 | NCX, Na+ | PDE4D3, phosphodiesterase 4D3 | CICR, Ca2+ induced Ca2+ release | SR, sarcoplasmic reticulum | PP2A, protein phosphatase 2A | SCD, sudden cardiac death | AP, action potential | 2, ryanodine receptor type-1 | CSQ, calsequestrin | SOICR, store-overload-induced Ca2+ release | CaMKII, Ca2 | P. Molenaar | P-1 or P-2, phosphatase inhibitor type-1 or type-2 | LCC, L-type Ca2+ channel | ECC, excitation–contraction coupling | SERCA, sarcoplasmic reticulum Ca2+ ATPase | PKA, protein kinase A
Journal Article
体力科学, ISSN 0039-906X, 2018, Volume 67, Issue 3, pp. 207 - 218
Ryanodine receptors (RyRs) are tetrameric Ca2+ release channels of sarcoplasmic reticulum (SR). This review attempts to detail the key mechanism of RyR channel... 
ryanodine receptor 1 | coupled gating | intracellular calcium ion | sarcoplasmic reticulum
Journal Article