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Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/2019, Volume 519, Issue 1, pp. 148 - 152
Hypertrophic cardiomyopathy is a commonly occurring cardiovascular disease resulting primarily from changes in proteins participating in muscle contraction in... 
Hypertrophic cardiomyopathy | In vitro motility | Calcium sensitivity | Myosin activity | Cardiac actin
Journal Article
The Journal of Physiology, ISSN 0022-3751, 09/2019, Volume 597, Issue 17, pp. 4435 - 4436
Journal Article
BMB Reports, ISSN 1976-6696, 2018, Volume 51, Issue 5, pp. 236 - 241
Anoctamin 1 (ANO1) is an anion channel that is activated by changes in cytosolic Ca2+ concentration and noxious heat. Although the critical roles of ANO1 have... 
Calcium sensitivity | Heat sensitivity | Anoctamin 1 | Ran-dom mutation
Journal Article
BIOPHYSICAL JOURNAL, ISSN 0006-3495, 08/2018, Volume 115, Issue 3, pp. 543 - 553
Cardiac muscle develops more force when it is activated at longer lengths. The concentration of Ca2+ required to develop half-maximal force also decreases.... 
SUPER-RELAXED STATE | SKELETAL-MUSCLE | HYPERTROPHIC CARDIOMYOPATHY | BIOPHYSICS | CARDIAC MYOSIN | THIN FILAMENT ACTIVATION | BINDING PROTEIN-C | SARCOMERE-LENGTH | MYOFILAMENT CALCIUM SENSITIVITY | RABBIT PSOAS | TROPONIN-I
Journal Article
Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology, ISSN 0174-1578, 01/2018, Volume 188, Issue 1, pp. 89 - 99
Intracellular taurine is abundant in many animals and it influences an array of physiological processes, including osmoregulation, metabolism, and cardiac... 
Glucose metabolism | Ryanodine | Taurine | Anoxia | Calcium sensitivity | Fish heart | Killifish | Reoxygenation
Journal Article
JOURNAL OF GENERAL PHYSIOLOGY, ISSN 0022-1295, 05/2019, Volume 151, Issue 5, pp. 610 - 613
The heart is a highly regulated system in which a combination of mechanisms work together to match cardiac output to the needs of the body. Loss of this... 
HEART | BINDING-PROTEIN-C | PHYSIOLOGY | FILAMENTS | MYOSIN | PHOSPHORYLATION | TITIN | MUSCLE | FRANK-STARLING MECHANISM | TENSION | CALCIUM SENSITIVITY | Heart | Diastole | Myosins | X-ray diffraction | Phosphorylation | Calcium | Contraction | Myosin
Journal Article
Advances in Pharmacology, ISSN 1054-3589, 2017, Volume 78, pp. 303 - 322
Vascular smooth muscle contraction is an important physiological process contributing to cardiovascular homeostasis. The principal determinant of smooth muscle... 
Rho | Vascular smooth muscle | Calcium | Calcium sensitivity | Rho kinase | Contractile function
Journal Article
JOURNAL OF PHYSIOLOGY-LONDON, ISSN 0022-3751, 03/2018, Volume 596, Issue 6, pp. 1079 - 1089
Skeletal muscle can develop a prolonged low frequency-stimulation force depression (PLFFD) following fatigue-inducing contractions. Increased levels of... 
INTRACELLULAR PO-2 | PEPTIDE ANTIOXIDANTS | O-2 TRANSPORT | COMPLEX-III | PHYSIOLOGY | SKELETAL-MUSCLE FIBERS | MOUSE MUSCLE | HYDROGEN-PEROXIDE | CONTRACTILE FUNCTION | CALCIUM SENSITIVITY | NEUROSCIENCES | OXYGEN SPECIES FORMATION
Journal Article
老年心脏病学杂志:英文版, ISSN 1671-5411, 2013, Volume 10, Issue 1, pp. 91 - 101
Genetic investigations of cardiomyopathy in the recent two decades have revealed a large number of mutations in the genes encoding sarcomeric proteins as a... 
Troponin | Calcium sensitivity | Cardiomyopathy | Muscle contraction | Review
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 07/2009, Volume 297, Issue 1, pp. H181 - H190
Journal Article
JOURNAL OF GENERAL PHYSIOLOGY, ISSN 0022-1295, 05/2019, Volume 151, Issue 5, pp. 619 - 622
The contractile proteins in myofibers, myofilaments, are arranged into repeating units called sarcomeres. As well as thick and thin filaments, each sarcomere... 
ACTIVATION | PHYSIOLOGY | FORCE GENERATION | TITIN | SARCOMERE | CARDIAC-MUSCLE | SKELETAL | THIN FILAMENT LENGTH | CALCIUM SENSITIVITY | IDENTIFICATION | CONNECTIN | Proteins | Connectin | Filaments | Contractility | Computer applications | Muscle contraction | Sarcomeres | Skeletal muscle
Journal Article
JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 05/2017, Volume 130, Issue 10, pp. 1772 - 1784
The neuromuscular junction (NMJ) is the synapse between motoneurons and skeletal muscle, and is responsible for eliciting muscle contraction. Neurotransmission... 
MYASTHENIC SYNDROME | Ageing | MUSCLE | Adhesion receptor | CALCIUM SENSITIVITY | Autophagy | CELL BIOLOGY | MOTOR-NERVE TERMINALS | TRANSMITTER RELEASE | Synapse | Neurodegeneration | ACTIVE ZONES | MOUSE MODEL | ALPHA 3 BETA-1-INTEGRIN | PS INTEGRINS
Journal Article
Circulation Research, ISSN 0009-7330, 06/2019, Volume 124, Issue 12, pp. 1760 - 1777
RATIONALE:PKA (Protein Kinase A) is a major mediator of β-AR (β-adrenergic) regulation of cardiac function, but other mediators have also been suggested.... 
protein kinases | heart rate | calcium | beta-adrenergic | cardiomyopathies | BINDING-PROTEIN-C | CARDIAC & CARDIOVASCULAR SYSTEMS | KINASE-A | PHOSPHORYLATION | PHOSPHOLAMBAN | CALCIUM SENSITIVITY | FAILURE | RESERVE | PERIPHERAL VASCULAR DISEASE | CHANNELS | HEMATOLOGY | MODULATION
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, ISSN 0363-6135, 09/2019, Volume 317, Issue 3, pp. H640 - H647
The force-frequency relationship (FFR) is an important regulatory mechanism that increases the force-generating capacity as well as the contraction and... 
heart failure | BINDING-PROTEIN-C | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | CONTRACTILITY | relaxation | CARDIOMYOPATHY | CALCIUM SENSITIVITY | FORCE-FREQUENCY-RELATIONSHIP | frequency | myofilaments | PHOSPHOLAMBAN PHOSPHORYLATION | DEPENDENT ACCELERATION | VENTRICULAR MYOCARDIUM | contraction | ISOMETRIC TENSION | PERIPHERAL VASCULAR DISEASE
Journal Article
Pflugers Archiv European Journal of Physiology, ISSN 0031-6768, 2009, Volume 458, Issue 6, pp. 1023 - 1038
Journal Article
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