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Journal of the American Chemical Society, ISSN 0002-7863, 06/2017, Volume 139, Issue 22, pp. 7595 - 7602
Journal Article
Cancer Research, ISSN 0008-5472, 05/2011, Volume 71, Issue 9, pp. 3364 - 3376
Journal Article
Oncogene, ISSN 0950-9232, 10/2013, Volume 32, Issue 44, pp. 5210 - 5219
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2009, Volume 106, Issue 38, pp. 16233 - 16238
Carbonic anhydrase (CA) IX is a plasma membrane-associated member of the α-CA enzyme family, which is involved in solid tumor acidification. It is a marker of... 
Enzymes | Molecules | Active sites | Memory interference | Crystals | Cell adhesion | Hypoxia | Dimers | Crystal structure | Tumors | CA-IX | ISOZYMES | PROTEIN-TYROSINE-PHOSPHATASES | MULTIDISCIPLINARY SCIENCES | RESOLUTION | INTRACELLULAR PH | EXTRACELLULAR DOMAIN | E-CADHERIN | PROTON-TRANSFER | HYPOXIA | REFINED STRUCTURE | Protons | Carbon Dioxide - chemistry | Carbonic Anhydrases - genetics | Humans | Protein Multimerization | Molecular Sequence Data | Crystallography, X-Ray | Structure-Activity Relationship | Carbonic Anhydrases - chemistry | Antigens, Neoplasm - chemistry | Carbonic Anhydrases - metabolism | Disulfides - chemistry | Enzyme Inhibitors - chemistry | Drug Design | Water - chemistry | Antigens, Neoplasm - metabolism | Bicarbonates - chemistry | Carbonic Anhydrase IX | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Amino Acid Sequence | Antigens, Neoplasm - genetics | Catalytic Domain | Carbon Dioxide - metabolism | Enzyme Inhibitors - metabolism | Crystallization | Enzyme Inhibitors - pharmacology | Water - metabolism | Models, Molecular | Neoplasms - enzymology | Recombinant Proteins - chemistry | Neoplasms - drug therapy | Sequence Homology, Amino Acid | Bicarbonates - metabolism | Protein Conformation | Kinetics | Neoplasms - pathology | Hydrogen-Ion Concentration | Structure | Proteins | Membranes | Molecular structure | Chemical compounds | Cell adhesion & migration | Index Medicus | Biological Sciences
Journal Article
Journal of Cell Science, ISSN 0021-9533, 04/2011, Volume 124, Issue 7, pp. 1077 - 1087
Journal Article
Journal Article
CELL CYCLE, ISSN 1538-4101, 06/2013, Volume 12, Issue 11, pp. 1791 - 1801
Extracellular acidification, a mandatory feature of several malignancies, has been mainly correlated with metabolic reprogramming of tumor cells toward Warburg... 
TUMOR-STROMA | SURVIVAL | OXIDATIVE STRESS | METASTASIS | FIBROBLASTS | CELL BIOLOGY | cancer-associated fibroblasts | prostate cancer | INVASION | carbonic anhydrase IX | acidity | METABOLISM | GROWTH | epithelial-mesenchymal transition | EXPRESSION
Journal Article
FEBS Letters, ISSN 0014-5793, 2004, Volume 577, Issue 3, pp. 439 - 445
Acidic extracellular pH (pHe) is a typical attribute of a tumor microenviroment, which has an impact on cancer development and treatment outcome. It was... 
Hypoxia | Carbonic anhydrase IX | Sulfonamide | Tumor microenvironment | Acidosis | pHe, extracellular pH | ΔCA, deletion mutant of CA IX lacking the catalytic domain | CAI, carbonic anhydrase inhibitor | CA, carbonic anhydrase | ΔPG, deletion mutant of CA IX lacking the proteoglycan-like domain | AE, anion exchanger | HIF, hypoxia inducible factor | MAb, monoclonal antibody | LACTIC-ACID | hypoxia | BIOCHEMISTRY & MOLECULAR BIOLOGY | SULFONAMIDES | ISOZYME-IX | CELL-LINES | CANCER | CELL BIOLOGY | ADHESION | carbonic anhydrase IX | BIOPHYSICS | sulfonamide | acidosis | IN-VIVO | TRANSPORT METABOLON | tumor microenvironment | INHIBITORS | VHL | Sequence Deletion | Carbonic Anhydrases - genetics | Humans | Gene Expression Regulation, Neoplastic | Carbonic Anhydrases - chemistry | Antigens, Neoplasm - chemistry | Biomarkers, Tumor | Carbonic Anhydrases - metabolism | Cell Hypoxia | Time Factors | Culture Media | Isoenzymes - metabolism | Enzyme Inhibitors - chemistry | Cloning, Molecular | Antigens, Neoplasm - metabolism | Molecular Structure | Carbonic Anhydrase IX | Protein Structure, Tertiary | Antigens, Neoplasm - genetics | Cell Line | Biotinylation | Acidosis - etiology | Sulfonamides - chemistry | Enzyme Inhibitors - pharmacology | Binding Sites - genetics | Sulfonamides - pharmacology | Precipitin Tests | Animals | Dogs | HeLa Cells | Antigens, Neoplasm - drug effects | Carbonic Anhydrases - drug effects | Hydrogen-Ion Concentration | Index Medicus
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2012, Volume 55, Issue 11, pp. 5591 - 5600
Journal Article
Cell Cycle, ISSN 1538-4101, 06/2013, Volume 12, Issue 11, pp. 1791 - 1801
Journal Article
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