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Drug Design, Development and Therapy, ISSN 1177-8881, 09/2014, Volume 8, pp. 1629 - 1647
Cratoxylum arborescens is an equatorial plant belonging to the family Guttiferae. In the current study, alpha-Mangostin (AM) was isolated and its cell death... 
NF-κB | Caspace 3/7 | Mitochondria | Protein array | α-Mangostin | Apoptosis | ACTIVATION | CHEMISTRY, MEDICINAL | RISK-FACTORS | INDUCED APOPTOSIS | mitochondria | apoptosis | CELL-CYCLE ARREST | ANTITUMOR-ACTIVITY | BCL2/BAX SIGNALING PATHWAYS | GARCINIA-MANGOSTANA | BREAST-CANCER CELLS | caspace 3/7 | protein array | NF-kappa B | alpha-Mangostin | HUMAN COLON-CANCER | PHARMACOLOGY & PHARMACY | CYTOCHROME-C RELEASE | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Humans | NF-kappa B - metabolism | Structure-Activity Relationship | Xanthones - pharmacology | Dose-Response Relationship, Drug | MCF-7 Cells | Female | Molecular Structure | Clusiaceae - chemistry | Xanthones - chemistry | Xanthones - isolation & purification | Cells, Cultured | Rats | Antineoplastic Agents, Phytogenic - chemistry | Breast Neoplasms - drug therapy | Rats, Sprague-Dawley | HSP70 Heat-Shock Proteins - metabolism | Mammary Neoplasms, Animal - pathology | Animals | Breast Neoplasms - pathology | Cell Proliferation - drug effects | Mammary Neoplasms, Animal - drug therapy | Antineoplastic Agents, Phytogenic - pharmacology | Antineoplastic Agents, Phytogenic - isolation & purification | Drug Screening Assays, Antitumor | Cytochrome | Reactive oxygen species | Animal models | Bax protein | Bcl-2 protein | Toxicity | Membrane permeability | Fluorescence | Cytotoxicity | Immunoblotting | ADP | Cytosol | Ingestion | Proteins | Ribose | Modulation | Biocompatibility | Membrane potential | Translocation | NF-κB protein | Cell permeability | Tumor cells | Mortality | Heat shock proteins | Breast cancer | Hsp70 protein | Lymphoma | Polymerase | Cytochrome c | Lymphocytes B | Cell death | Cytochromes | Nuclei (cytology) | Immunofluorescence | Cytoplasm | Heat shock | Tumors | B-cell lymphoma | Index Medicus
Journal Article
Journal Article
Molecular and Cellular Biochemistry, ISSN 0300-8177, 1/2003, Volume 243, Issue 1, pp. 15 - 22
Poly(ADP-ribose) polymerase-1 (PARP-1) is the canonical member of the PARP family of enzymes and modulates many crucial nuclear functions. PARP-1 is involved... 
Life Sciences | Biochemistry, general | caspase cleavage site | posttranslational modification | recombinant protein | Medical Biochemistry | Oncology | prokaryotic expression | Cardiology | Posttranslational modification | Prokaryotic exprtession | Recombinant protein | Caspace cleavage site | Mutation | Apoptosis
Journal Article
01/2005, ISBN 0471219479, 19
This chapter contains sections titled: Caspase‐Independent Mechanisms of Death, the Case for Nonanimal Models, and the Choice of Dictyostelium Main Features of... 
vacuolar cell death | misleading mutants | caspace‐independent cell death
Book Chapter
01/2005, ISBN 0471219479, 21
This chapter contains sections titled: Mitochondria: Central Components in the Activation of Apoptosis Multiple Routes and Mechanisms of Cytochrome c Release... 
cytochrome c release and caspace activity | mitochondria and oxidation | oxidative stress
Book Chapter
01/2005, ISBN 0471219479, 21
This chapter contains sections titled: Mechanisms of Apoptosis Apoptosis and Cancer Apoptosis Pathways in Cancer Therapy Conclusion References 
cancer biology | initiator and effector caspaces | tissue homeostasis
Book Chapter
Reviews in the Neurosciences, ISSN 0334-1763, 2001, Volume 12, Issue 1, pp. 41 - 50
Journal Article
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