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Journal Article
Endocrine-Related Cancer, ISSN 1351-0088, 10/2014, Volume 21, Issue 5, pp. 691 - 704
Journal Article
Journal Article
Nature, ISSN 0028-0836, 04/2011, Volume 472, Issue 7343, pp. 319 - 324
Journal Article
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 01/2010, Volume 42, Issue 1, pp. 21 - 24
Caspase-7 was considered to be redundant with caspase-3 because these related cysteine proteases share an optimal peptide recognition sequence and have several... 
Caspase-7 | Inflammation | Caspase-3 | Apoptosis | ACTIVATION | GENE | SUBSTRATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISTINCT | CELL BIOLOGY | Caspase 7 - metabolism | Inflammation - pathology | Inflammation - therapy | Animals | Caspase 7 - chemistry | Humans | Inflammation - enzymology | Cysteine | Peptides | Proteases | Mitogens | apoptosis | caspase-7 | inflammation | caspase-3
Journal Article
British Journal of Cancer, ISSN 0007-0920, 01/2016, Volume 114, Issue 2, pp. 177 - 187
Background: Oestrogen receptor-negative (ER-) breast cancer is intrinsically sensitive to chemotherapy. However, tumour response is often incomplete, and... 
CELLS | REDUCES TUMOR-GROWTH | STAT1 | DNA-DAMAGE | chemotherapy | IFN | THERAPY | NEOADJUVANT CHEMOTHERAPY | ONCOLOGY | ER-negative breast cancer | GENE-EXPRESSION | RESISTANCE | PATHWAY ANALYSIS | predictive signature | XENOGRAFTS | Caspase 7 - metabolism | Immunohistochemistry | Receptors, Estrogen - metabolism | Cytoskeletal Proteins - genetics | Humans | Intracellular Signaling Peptides and Proteins - drug effects | Caspase 3 - metabolism | Gene Expression Profiling | Intracellular Signaling Peptides and Proteins - metabolism | Interferon-gamma - metabolism | Carrier Proteins - drug effects | Mitochondrial Proteins - drug effects | STAT1 Transcription Factor - metabolism | Mitochondrial Proteins - metabolism | Caspase 3 - genetics | Interferon-beta - genetics | Cytokines - genetics | Intracellular Signaling Peptides and Proteins - genetics | Real-Time Polymerase Chain Reaction | Ubiquitins - metabolism | Caspase 7 - drug effects | Antigens - drug effects | Caspase 7 - genetics | Membrane Proteins - genetics | Myxovirus Resistance Proteins - drug effects | Capecitabine - pharmacology | STAT1 Transcription Factor - genetics | Breast Neoplasms - drug therapy | Blotting, Western | Breast Neoplasms - genetics | Interferon-beta - metabolism | Signal Transduction - drug effects | Mice, Nude | Membrane Proteins - drug effects | Mice | Myxovirus Resistance Proteins - genetics | Ubiquitins - drug effects | Antigens - genetics | Neoplasm Transplantation | Phosphorylation | Ubiquitins - genetics | Gene Expression Regulation, Neoplastic | Interferon-gamma - drug effects | STAT1 Transcription Factor - drug effects | Mitochondrial Proteins - genetics | Interferon-beta - drug effects | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Breast Neoplasms - metabolism | In Situ Hybridization | Caspase 3 - drug effects | Cytoskeletal Proteins - metabolism | Female | Cytoskeletal Proteins - drug effects | Membrane Proteins - metabolism | Interferon-gamma - genetics | Cytokines - metabolism | Antigens - metabolism | Cisplatin - pharmacology | Xenograft Model Antitumor Assays | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Cytokines - drug effects | Myxovirus Resistance Proteins - metabolism | Translational Therapeutics
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2011, Volume 108, Issue 12, pp. 4834 - 4839
A specific small-molecule inhibitor of p97 would provide an important tool to investigate diverse functions of this essential ATPase associated with diverse... 
Proteins | HEK293 cells | Cell death | Ubiquitins | Adenosine triphosphatases | Cell lines | HeLa cells | Small interfering RNA | Inhibitory concentration 50 | Apoptosis | Autophagy | Unfolded protein response | CANCER-CELLS | MULTIPLE-MYELOMA | autophagy | PROTEASOME INHIBITION | ER STRESS | MULTIDISCIPLINARY SCIENCES | apoptosis | ENDOPLASMIC-RETICULUM STRESS | SACCHAROMYCES-CEREVISIAE | AAA-ATPASE CDC48/P97 | unfolded protein response | P97/VALOSIN-CONTAINING PROTEIN | ONCOGENE ADDICTION | Caspase 7 - metabolism | Quinazolines - chemical synthesis | Antineoplastic Agents - chemical synthesis | Humans | Caspase 3 - metabolism | Ubiquitin - metabolism | Enzyme Inhibitors - chemical synthesis | Autophagy - drug effects | Enzyme Inhibitors - chemistry | Caspase 3 - genetics | Antineoplastic Agents - pharmacology | Nuclear Proteins - genetics | Quinazolines - chemistry | Endoplasmic Reticulum - enzymology | Cell Line | Endoplasmic Reticulum - genetics | Caspase 7 - genetics | Enzyme Inhibitors - pharmacology | Adenosine Triphosphatases - metabolism | Neoplasms - enzymology | Nuclear Proteins - metabolism | Ubiquitin - genetics | Antineoplastic Agents - chemistry | Neoplasms - drug therapy | Proteasome Endopeptidase Complex - genetics | Adenosine Triphosphatases - antagonists & inhibitors | Animals | Nuclear Proteins - antagonists & inhibitors | Adenosine Triphosphatases - genetics | Mice | Proteasome Endopeptidase Complex - metabolism | Quinazolines - pharmacology | Ubiquitin | Autophagy (Cytology) | Enzyme inhibitors | Proteolysis | Genetic aspects | Research | Properties | Biological Sciences | Physical Sciences
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, p. e89040
Journal Article
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 02/2014, Volume 189, Issue 3, pp. 282 - 291
Journal Article