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Kidney international, ISSN 0085-2538, 05/2019
Inflammation and tubular cell death are the hallmarks of acute kidney injury (AKI). However, the precise mechanism underlying these effects has not been fully... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2016, Volume 113, Issue 28, pp. 7858 - 7863
Gasdermin-D (GsdmD) is a critical mediator of innate immune defense because its cleavage by the inflammatory caspases 1, 4, 5, and 11 yields an N-terminal p30... 
GsdmD | Caspase-11 | Pyroptosis | DOMAIN | MECHANISM | MULTIDISCIPLINARY SCIENCES | PLATFORMS | caspase-11 | NONCANONICAL INFLAMMASOME ACTIVATION | PERFRINGOLYSIN-O | CELL-DEATH | pyroptosis | MICRODOMAINS | LEADS | INTRACELLULAR LPS | BINDING | Animals | Caspases - metabolism | Humans | Neoplasm Proteins - physiology | HEK293 Cells | Mice | Liposomes | Mutation | Health aspects | Immunoproteins | Apoptosis | Biological Sciences
Journal Article
Journal of Immunology, ISSN 0022-1767, 12/2018, Volume 201, Issue 12, pp. 3662 - 3668
The DNA sensor absent in melanoma 2 (AIM2) forms an inflammasome complex with ASC and caspase-1 in response to Francisella tularensis subspecies novicida... 
GSDMD | MECHANISM | TULARENSIS | INFECTION | PYROPTOSIS | SECRETION | IMMUNOLOGY | D PORE | CASPASE-11 | INNATE IMMUNITY | CELL-DEATH
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 12/2019, Volume 245, p. 112161
Benth. Mainly found in Ecuador and Colombia has been ethnopharmacologically utilized as a remedy for various female disorders with kidney inflammation and... 
NF-κB | Viburnum pichinchense | Anti-inflammatory | Caspase-11 non-canonical inflammasome | Gastritis | Macrophage
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 2/2014, Volume 192, Issue 4, pp. 1835 - 1846
The Nlrp3 inflammasome is critical for host immunity, but the mechanisms controlling its activation are enigmatic. Here, we show that loss of FADD or caspase-8... 
caspase-8 | NLR | inflammasome | NLRP3 | caspase-11 | FADD | caspase-1
Journal Article
Journal Article
Science, ISSN 0036-8075, 9/2013, Volume 341, Issue 6151, pp. 1246 - 1249
Journal Article
Journal Article
mBio, ISSN 2161-2129, 09/2017, Volume 8, Issue 5, p. e01188-17
Journal Article
Cell death and differentiation, ISSN 1350-9047, 02/2019, Volume 26, Issue 11, pp. 2386 - 2399
The non-canonical inflammasome plays important roles in endotoxic shock and pyroptosis. Murine caspase-11, corresponding to human caspase-4, is centrally... 
Biodegradation | Ubiquitin | Shock | Caspase-11 | Caspase | Nedd4 protein | Inflammation | Caspase-4 | Lipopolysaccharides | Ubiquitination | Cell death | Sepsis | Endotoxemia | Ubiquitin-protein ligase
Journal Article