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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2010, Volume 107, Issue 21, pp. 9777 - 9782
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2012, Volume 109, Issue 22, pp. 8576 - 8581
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 11/2017, Volume 9, Issue 11, pp. 1589 - 1604
Hepatoblastoma is the most common malignant pediatric liver cancer. Histological evaluation of tumor biopsies is used to distinguish among the different... 
glucose transporter | pediatric liver cancer | glycolysis | mutant β‐catenin | mutant β-catenin | MEDICINE, RESEARCH & EXPERIMENTAL | HEPATIC GLUCONEOGENESIS | HEXOKINASE 2 | ACTIVATION | CRYSTAL-STRUCTURE | mutant beta-catenin | BETA-CATENIN | CANCER | WNT/BETA-CATENIN | ALPHA-CATENIN | WNT | Humans | Fetus - metabolism | Glucose Transporter Type 3 - metabolism | Glycolysis - genetics | Transcription Factor 4 - metabolism | RNA Interference | Liver Neoplasms - pathology | Hexokinase - genetics | Child | Hepatoblastoma - metabolism | Hepatoblastoma - pathology | Hexokinase - antagonists & inhibitors | Transcription Factor 4 - genetics | Proto-Oncogene Proteins c-myc - metabolism | beta Catenin - metabolism | beta Catenin - genetics | Gluconeogenesis - genetics | beta Catenin - antagonists & inhibitors | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Proto-Oncogene Proteins c-myc - antagonists & inhibitors | Cell Line, Tumor | Proto-Oncogene Proteins c-myc - genetics | Mutation | Hexokinase - metabolism | Carcinoma, Hepatocellular - metabolism | RNA, Small Interfering - metabolism | Immunohistochemistry | RNA sequencing | Glucose metabolism | Enzymes | Liver cancer | RNA | Analysis | Glucose | Dextrose | Glucose transporter | Pediatrics | Wnt protein | Tumor cells | Fetuses | Hepatocellular carcinoma | Carbohydrate metabolism | Malignancy | Tumor cell lines | Metabolism | Ribonucleic acid--RNA | Fatty acids | Hexokinase | Hepatocytes | Glycolysis | Oxidation | Catenin | Gluconeogenesis | Index Medicus | Digestive System | Systems Medicine | Cancer
Journal Article
Development, ISSN 0950-1991, 01/2012, Volume 125, Issue 1, pp. 233 - 245
alpha-catenin associates the cadherin-catenin complex with the actin cytoskeleton. a-catenin binds to beta-catenin, which links it to the cadherin cytoplasmic... 
Oogenesis | Arp2/3 | Head morphogenesis | Drosophila | DE-cadherin:: α-catenin fusion protein | α-catenin | Cadherin | Adherens junction | De-cadherin::α-catenin fusion protein | CADHERIN-BASED ADHESION | ARP2/3 COMPLEX | ACTIN DYNAMICS | BETA-CATENIN | alpha-Catenin | POLARITY GENE ARMADILLO | CELL BIOLOGY | CAENORHABDITIS-ELEGANS | DE-CADHERIN | EPITHELIAL MORPHOGENESIS | TUMOR-SUPPRESSOR | CELL-CELL ADHESION | DE-cadherin::alpha-Catenin fusion protein | Embryo, Nonmammalian - cytology | Cadherins - metabolism | alpha Catenin - metabolism | Embryo, Nonmammalian - metabolism | Zygote - metabolism | Actin-Related Protein 2-3 Complex - genetics | Embryo, Nonmammalian - embryology | Male | Armadillo Domain Proteins - genetics | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Adherens Junctions - metabolism | Drosophila melanogaster - metabolism | Actin-Related Protein 2-3 Complex - metabolism | Gene Deletion | Larva - growth & development | Female | Spectrin - metabolism | Ovarian Follicle - cytology | Ovarian Follicle - metabolism | Adherens Junctions - genetics | Drosophila melanogaster - cytology | Embryonic Development - genetics | Head - growth & development | Transcription Factors - genetics | Oogenesis - genetics | Transcription Factors - metabolism | Phenotype | alpha Catenin - deficiency | Animals | Mutagenesis | Armadillo Domain Proteins - metabolism | Imaginal Discs - metabolism | Drosophila melanogaster - growth & development | alpha Catenin - genetics | Drosophila Proteins - genetics | Index Medicus
Journal Article
The EMBO Journal, ISSN 0261-4189, 07/2013, Volume 32, Issue 13, pp. 1903 - 1916
The Wnt/β‐catenin signalling and autophagy pathways each play important roles during development, adult tissue homeostasis and tumorigenesis. Here we identify... 
cancer | autophagy | LC3 | p62 | Wnt/β‐catenin | Autophagy | Wnt/β-catenin | Cancer | CELLS | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | P62/SQSTM1 | CASPASE CLEAVAGE | SELECTIVE AUTOPHAGY | CELL BIOLOGY | TRANSCRIPTION FACTOR NRF2 | STRUCTURAL BASIS | COLORECTAL-CANCER | Wnt/beta-catenin | RNA, Small Interfering - genetics | Colonic Neoplasms - genetics | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Sequestosome-1 Protein | Humans | Wnt Proteins - metabolism | Antigens, CD - genetics | Colonic Neoplasms - metabolism | Immunoenzyme Techniques | Antigens, CD - metabolism | Lysosomes - metabolism | Wnt Proteins - genetics | Chromatin Immunoprecipitation | Proteolysis | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Recombinant Proteins - metabolism | Transcription Factor 4 | Leukocyte Immunoglobulin-like Receptor B1 | Phagosomes - metabolism | RNA, Messenger - genetics | Recombinant Proteins - genetics | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | beta Catenin - metabolism | Blotting, Western | beta Catenin - genetics | Mice, Knockout | Transcription Factors - metabolism | Animals | beta Catenin - antagonists & inhibitors | Colonic Neoplasms - pathology | Adaptor Proteins, Signal Transducing - genetics | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Fluorescent Antibody Technique | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Mice | Proteasome Endopeptidase Complex - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Receptors, Immunologic - genetics | Receptors, Immunologic - metabolism | Index Medicus | β-catenin | Wnt
Journal Article
Journal Article
Kidney International, ISSN 0085-2538, 09/2012, Volume 82, Issue 5, pp. 537 - 547
β-Catenin is a unique intracellular protein functioning as an integral component of the cell–cell adherens complex and a principal signaling protein mediating... 
β-catenin | apoptosis | acute kidney injury | Wnt | beta-catenin | INTEGRIN-LINKED KINASE | PROAPOPTOTIC BAX | GAMMA-CATENIN | MECHANISMS | PODOCYTE INJURY | EPITHELIAL-CELLS | UROLOGY & NEPHROLOGY | AMELIORATES PROTEINURIA | UP-REGULATION | RENAL INTERSTITIAL FIBROSIS | Reperfusion Injury - etiology | Wnt1 Protein - genetics | Phosphorylation | Epithelial Cells - metabolism | Cadherins - metabolism | Inhibitor of Apoptosis Proteins - genetics | Humans | Acute Kidney Injury - genetics | Wnt1 Protein - metabolism | Adherens Junctions - metabolism | Transfection | Time Factors | Acute Kidney Injury - chemically induced | Inhibitor of Apoptosis Proteins - metabolism | Kidney Tubules - pathology | Kidney Tubules - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Reperfusion Injury - genetics | Reperfusion Injury - metabolism | Repressor Proteins - metabolism | Disease Models, Animal | Folic Acid | Cell Line | Reperfusion Injury - pathology | Acute Kidney Injury - pathology | Mice, Inbred C57BL | beta Catenin - deficiency | Tumor Suppressor Protein p53 - metabolism | bcl-2-Associated X Protein - metabolism | gamma Catenin - metabolism | Repressor Proteins - genetics | Genotype | Survivin | beta Catenin - metabolism | beta Catenin - genetics | Mice, Knockout | Phenotype | Animals | Creatinine - blood | Mice | Acute Kidney Injury - metabolism | Apoptosis | Index Medicus
Journal Article