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by Yang, HJ and Xi, XX and Zhao, B and Su, ZX and Wang, ZY
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 01/2018, Volume 495, Issue 3, pp. 2376 - 2382
In this study, we investigated the expression profile and functional role of Kruppel-like family of transcription factor 4 (KLF4) in mouse cerebral... 
BIOPHYSICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BARRIER FUNCTION | MALAT1 | Inflammation | Ischemic stroke | KAPPA-B | KLF4 | CEREBRAL-ISCHEMIA | EXPRESSION | Endothelial cells | Apoptosis
Journal Article
Brain Research, ISSN 0006-8993, 2016, Volume 1657, pp. 167 - 175
Graphical abstract 
Neurology | Calcium signaling | Blood-brain barrier | Cerebral microvasculature | Protease-activated receptor 1 | blood-brain barrier | L-NAME | nitric oxide | BBB | protease-activated receptor 1 | RBMVEC | NG-nitro-L-arginine methyl ester | concentration | units | rat brain microvascular endothelial cells | PAR1 | inositol 1,4,5-trisphosphate | Ca | cytosolic Ca | ENTRY | BARRIER PERMEABILITY | MITOCHONDRIA | RECEPTOR | CYTOSOLIC CALCIUM | NEUROSCIENCES | IN-VITRO | INDUCED INCREASE | PHARMACOLOGY | NITRIC-OXIDE | CHANNELS | Capillary Permeability - physiology | Thrombin - administration & dosage | Reactive Oxygen Species - metabolism | Calcium - metabolism | Receptor, PAR-1 - metabolism | Calcium Signaling - physiology | Humans | Actins - metabolism | Microvessels - metabolism | Capillary Permeability - drug effects | Endoplasmic Reticulum - metabolism | Nitric Oxide Synthase - antagonists & inhibitors | Cardiovascular Agents - metabolism | Inositol 1,4,5-Trisphosphate Receptors - metabolism | Endoplasmic Reticulum - drug effects | Tight Junctions - drug effects | Tight Junctions - metabolism | Cell Line | Cardiovascular Agents - administration & dosage | Receptor, PAR-1 - antagonists & inhibitors | Endothelial Cells - metabolism | Microvessels - drug effects | Rats | Mitochondria - metabolism | Mitochondria - drug effects | Blood-Brain Barrier - drug effects | Blood-Brain Barrier - metabolism | Animals | Calcium Signaling - drug effects | Nitric Oxide Synthase - metabolism | Thrombin - metabolism | Nitric Oxide - metabolism | Endothelial Cells - drug effects | Thrombin | Endothelium | Medical colleges | Inositol | Actin | Nitric oxide | Permeability | Muscle proteins | cerebral microvasculature | calcium signaling
Journal Article
Neuroscience Letters, ISSN 0304-3940, 04/2017, Volume 645, pp. 60 - 66
Journal Article
Journal Article
by Zhu, HY and Dai, RR and Zhou, YQ and Fu, H and Meng, Q
NEUROCHEMICAL RESEARCH, ISSN 0364-3190, 10/2018, Volume 43, Issue 10, pp. 1897 - 1904
Blood-brain barrier (BBB) destruction is associated with a variety of neurological diseases. Brain microvascular endothelial cells (BMECs) are the key... 
IMMUNITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | BARRIER | Matrix metalloproteinase | NEUROSCIENCES | DAMAGE | STROKE | Brain microvascular endothelial cells | MATRIX METALLOPROTEINASES | INFLAMMATION | Toll-like receptor-2 | TOLL-LIKE RECEPTORS | Pam3CSK4 | TIMPS | CEREBRAL-ISCHEMIA | Mitogen-activated protein kinases
Journal Article
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 10/2015, Volume 135, Issue 2, pp. 431 - 440
Journal Article
Microvascular Research, ISSN 0026-2862, 03/2012, Volume 83, Issue 2, pp. 138 - 145
Hypoxia is increasingly recognized as an important contributing factor to the development of brain diseases such as Alzheimer's disease (AD). In the periphery,... 
ALZHEIMERS-DISEASE BRAIN | INDUCIBLE FACTOR-I | NITRIC-OXIDE SYNTHASE | NEUROVASCULAR DYSFUNCTION | VEGF | NEURODEGENERATION | PERIPHERAL VASCULAR DISEASE | HEME OXYGENASE-1 GENE | GROWTH-FACTOR | CEREBRAL-ISCHEMIA | EXPRESSION | Angiogenic Proteins - genetics | Microvessels - metabolism | Microvessels - pathology | Vascular Endothelial Growth Factor A - metabolism | RNA, Messenger - metabolism | Oxygen - metabolism | Cell Hypoxia | Brain - blood supply | Time Factors | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Nitric Oxide Synthase Type III - metabolism | Heme Oxygenase (Decyclizing) - metabolism | Enzyme-Linked Immunosorbent Assay | Cell Survival | Endothelial Cells - metabolism | Endothelin-1 - metabolism | Cells, Cultured | Gene Expression Regulation | Rats | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Phenotype | Animals | Endothelial Cells - pathology | Angiogenic Proteins - metabolism | Thrombospondins - metabolism | Neovascularization, Physiologic | Nitrogen oxide | Development and progression | Endothelial growth factors | Alzheimer's disease | Endothelium | Nitric oxide | Amyloid beta-protein | Neovascularization | cerebral hypoperfusion | vascular endothelial growth factor | Hypoxia | heme oxygenase-1 | endothelin-1 | Alzheimer’s | brain microvascular endothelial cells
Journal Article