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European Journal of Organic Chemistry, ISSN 1434-193X, 12/2017, Volume 2017, Issue 46, pp. 6931 - 6941
A solid support and two phosphoramidites exhibiting a phthalimide–oxy group were synthesized. First, after treatment with hydrazine, the resulting 5′‐ and... 
Ligation | Click chemistry | Aldehydes | DNA | Oligonucleotides | Medicinal Chemistry | Analytical chemistry | Organic chemistry | Chemical Sciences
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 02/2012, Volume 134, Issue 8, pp. 3912 - 3916
Application of native chemical ligation logic to the case of an N-terminal proline is described. Two approaches were studied. One involved incorporation of a... 
PEPTIDES | SELENOCARBOXYLATES | NATIVE CHEMICAL LIGATION | VALINE | SITES | PROTEINS | CHEMISTRY, MULTIDISCIPLINARY | Erythropoietin - chemical synthesis | Erythropoietin - chemistry | Molecular Structure | Proline - analogs & derivatives | Stereoisomerism | Proline - chemistry | Proline | Chemical properties | Structure | Analysis | Peptide bonds
Journal Article
Accounts of Chemical Research, ISSN 0001-4842, 09/2017, Volume 50, Issue 9, pp. 2104 - 2115
The coupling of an alpha-ketoacid and a hydroxylamine (KAHA ligation) affords amide bonds under aqueous, acidic conditions without the need for protecting... 
5-OXAPROLINE | ACID | PEPTIDES | HORMONE | KAHA LIGATIONS | AS-48 | BETATROPHIN | FORMING LIGATIONS | CHEMISTRY, MULTIDISCIPLINARY | WATER | Solid-Phase Synthesis Techniques | Hydroxylamine - chemistry | Macrocyclic Compounds - chemistry | Proteins - chemical synthesis | Keto Acids - chemistry
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 05/2016, Volume 138, Issue 17, pp. 5499 - 5502
The use of small, natural chemical reporters in conjunction with catalyst-free bioorthogonal reactions will greatly streamline protein labeling in a cellular... 
MOTIFS | IN-VITRO | PROTEIN | NITRILE | REACTIVITY | CHEMISTRY | CYSTEINE | CONDENSATION | TAG | CHEMISTRY, MULTIDISCIPLINARY | PROBES | Cysteine | Chemical properties | Research | Peptides | Escherichia coli | Ligands (Biochemistry) | Index Medicus | Communication
Journal Article
Chemical Society Reviews, ISSN 0306-0012, 09/2011, Volume 40, Issue 9, pp. 4840 - 4871
Bioconjugation techniques using organic azides are compared in this critical review. A particular focus is on chemical ligation reactions and their application... 
O-LINKED GLYCOSYLATION | LIVING ANIMALS | 1,3-DIPOLAR CYCLOADDITIONS | CLICK CHEMISTRY | MUCIN-TYPE | NATIVE CHEMICAL LIGATION | PROTEIN-TYROSINE PHOSPHATASES | GLCNAC-MODIFIED PROTEINS | SYNTHETIC PEPTIDES | CHEMOSELECTIVE SYNTHESIS | CHEMISTRY, MULTIDISCIPLINARY | Azides - chemistry | Organic Chemicals - chemistry | Organic Chemistry Phenomena
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 08/2007, Volume 129, Issue 33, pp. 10064 - 10065
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 06/2011, Volume 133, Issue 25, pp. 9646 - 9649
Computation was used to design a transcyclooctene derivative that displays enhanced reactivity in the tetrazine-trans-cycloctene ligation. The optimized... 
CELLS | ALKENES | 1,3-DIPOLAR CYCLOADDITIONS | DIELS-ALDER REACTIONS | IN-VIVO | COPPER-FREE | FREE CLICK CHEMISTRY | SELECTIVITY | CHEMISTRY, MULTIDISCIPLINARY | Stereoisomerism | Cyclooctanes - chemical synthesis | Molecular Structure | Molecular structure | Structure | Cycloalkenes | Analysis
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