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2015, Topics in Medicinal Chemistry, ISBN 3319140604, Volume 14
Web Resource
Immunological Reviews, ISSN 0105-2896, 05/2019, Volume 289, Issue 1, pp. 5 - 8
Journal Article
2009, 1st ed., Methods in enzymology, ISBN 9780123749079, Volume 460-461
Web Resource
American journal of respiratory cell and molecular biology, ISSN 1044-1549, 11/2015, Volume 53, Issue 5, pp. 676 - 688
Macrophages are dynamic cells that mature under the influence of signals from the local microenvironment into either classically (M1) or alternatively (M2)... 
classically activated macrophages (CAM/M1) | Phagocytosis/ endocytosis | phagocytosis/endocytosis | phenotypic stability | alternatively activated macrophages (AAM/M2) | reprogramming of polarization | PHAGOCYTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MONOCYTES | DIFFERENTIAL REGULATION | MURINE | CELL BIOLOGY | GM-CSF | RESPIRATORY SYSTEM | THP-1 CELLS | MANNOSE | RECEPTOR-ACTIVITY | POLARIZATION | EXPRESSION | Chemokines, CC - secretion | Gene Expression - drug effects | Monocytes - cytology | Humans | Monocytes - immunology | Chemokine CCL5 - secretion | Chemokine CCL17 - secretion | Chemokine CXCL10 - biosynthesis | Interleukin-4 - pharmacology | Chemokine CCL17 - biosynthesis | Gene Expression - immunology | Chemokines, CC - biosynthesis | Interleukin-8 - secretion | Cell Differentiation | Interleukin-1beta - biosynthesis | Macrophages - immunology | Endocytosis - immunology | Interleukin-1beta - secretion | Interleukin-8 - biosynthesis | Endocytosis - drug effects | Tumor Necrosis Factor-alpha - secretion | Immunophenotyping | Macrophages - cytology | Interleukin-13 - pharmacology | Monocytes - drug effects | Chemokine CCL5 - biosynthesis | Chemokine CXCL10 - secretion | Lipopolysaccharides - pharmacology | Macrophages - drug effects | Primary Cell Culture | Macrophage Activation - drug effects | Tumor Necrosis Factor-alpha - biosynthesis | Interferon-gamma - pharmacology | Studies | Biology | Immunology | Blood & organ donations | Cytokines | Gene expression | Index Medicus
Journal Article
The Journal of Immunology, ISSN 0022-1767, 06/2005, Volume 174, Issue 12, pp. 8183 - 8190
Journal Article
Nature, ISSN 0028-0836, 11/2015, Volume 527, Issue 7577, pp. 249 - 253
Epigenetic silencing including histone modifications and DNA methylation is an important tumorigenic mechanism. However, its role in cancer immunopathology and... 
Polycomb Repressive Complex 2 - antagonists & inhibitors | CD8-Positive T-Lymphocytes - cytology | Immunotherapy - methods | Prognosis | Histones - chemistry | Chemokine CXCL9 - biosynthesis | Humans | Ovarian Neoplasms - pathology | DNA (Cytosine-5-)-Methyltransferases - antagonists & inhibitors | Th1 Cells - immunology | DNA (Cytosine-5-)-Methyltransferases - metabolism | Th1 Cells - metabolism | Chemokine CXCL10 - biosynthesis | Chemokine CXCL10 - immunology | Female | Epigenesis, Genetic - drug effects | Lysine - metabolism | Tumor Cells, Cultured | Chemokines - immunology | Tumor Escape - immunology | Chemokines - biosynthesis | DNA (Cytosine-5-)-Methyltransferase 1 | Gene Silencing | Chemokine CXCL9 - immunology | Chemokine CXCL9 - genetics | Chemokines - genetics | Enhancer of Zeste Homolog 2 Protein | Ovarian Neoplasms - enzymology | Xenograft Model Antitumor Assays | B7-H1 Antigen - metabolism | Animals | Chemokine CXCL10 - genetics | Ovarian Neoplasms - therapy | Mice | Histones - metabolism | CD8-Positive T-Lymphocytes - immunology | Polycomb Repressive Complex 2 - metabolism | DNA Methylation - drug effects | Lymphocytes, Tumor-Infiltrating - immunology | Ovarian Neoplasms - immunology | Index Medicus | checkpoint | CXCL9 | histone modification | chemotherapy | epigenetics | Chemokine | CXCL10 | DNMT | T cell therapy | DNA methylation | PD-L1 | B7-H1 | cancer | trafficking | PD-1 | EZH2
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2011, Volume 286, Issue 9, pp. 7214 - 7226
The Ca2+-binding protein of the EF-hand type, S100B, is abundantly expressed in and secreted by astrocytes, and release of S100B from damaged astrocytes occurs... 
CYTOPLASMIC DOMAIN | KAPPA-B ACTIVATION | IN-VITRO | NEURITE OUTGROWTH | INFLAMMATORY RESPONSES | BRAIN-INJURY | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NITRIC-OXIDE | GROWTH-FACTOR | GLYCATION END-PRODUCTS | Microglia - metabolism | Chemokine CCL3 - immunology | Nerve Growth Factors - metabolism | S100 Proteins - immunology | Cell Movement - immunology | S100 Proteins - genetics | Chemokine CXCL12 - genetics | Microglia - immunology | Chemokine CCL3 - genetics | Calcium-Binding Proteins - immunology | Cattle | Encephalitis - metabolism | Chemokine CCL3 - metabolism | Chemokine CCL5 - metabolism | Receptors, Immunologic - immunology | Receptor for Advanced Glycation End Products | Chemokine CXCL12 - immunology | Chemokines - immunology | Calcium-Binding Proteins - metabolism | Microglia - cytology | Recombinant Proteins - metabolism | Cell Line | S100 Calcium Binding Protein beta Subunit | Mice, Inbred C57BL | Rats | Encephalitis - immunology | S100 Proteins - metabolism | Nerve Growth Factors - immunology | Recombinant Proteins - genetics | Chemokines - genetics | Animals | Carrier Proteins - metabolism | Chemokine CXCL12 - metabolism | Recombinant Proteins - immunology | Up-Regulation - immunology | Nerve Growth Factors - genetics | Chemokine CCL5 - genetics | Cytoskeleton - metabolism | Chemokines - metabolism | Mice | Receptors, Immunologic - genetics | Chemokine CCL5 - immunology | Receptors, Immunologic - metabolism | Calcium-Binding Proteins - genetics | Index Medicus | Immunology | Defensins | Signal Transduction | Neurodegeneration | Migration | Calcium-binding Proteins | Innate Immunity | RAGE | S100B | Chemokines | Microglia
Journal Article
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 02/2004, Volume 94, Issue 2, pp. 253 - 261
ABSTRACT—Increasing evidence supports the involvement of inflammation in the early phases of atherogenesis. Recruitment of leukocytes within the vascular wall,... 
Atherogenesis | Leukocytes | Chemokine receptor antagonists | Chemokines | Vascular cells | atherogenesis | chemokine receptor antagonists | CARDIAC & CARDIOVASCULAR SYSTEMS | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | INDUCED LUNG INJURY | LESION FORMATION | DEFICIENT MICE | chemokines | KNOCKOUT MICE | vascular cells | IN-VIVO | leukocytes | MACROPHAGE INFLAMMATORY PROTEIN-2 | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | EXPRESSION | CC-CHEMOKINES | LYMPHOCYTES | Cholesterol, Dietary - toxicity | Apolipoproteins E - deficiency | Vasculitis - pathology | Male | Vasculitis - prevention & control | Chemokine CCL5 - analogs & derivatives | Chemotaxis, Leukocyte - drug effects | Receptors, Chemokine - biosynthesis | Receptors, LDL - deficiency | Chemokine CCL5 - metabolism | Receptors, Chemokine - antagonists & inhibitors | Receptors, CCR5 - physiology | Receptors, Chemokine - genetics | Receptors, Chemokine - drug effects | CCR5 Receptor Antagonists | Chemokines - biosynthesis | Aorta - drug effects | Mice, Inbred C57BL | RNA, Messenger - genetics | Chemokines - genetics | Mice, Knockout | Receptors, Chemokine - deficiency | Aorta - pathology | Gene Expression Regulation - drug effects | Arteriosclerosis - prevention & control | Animals | Chemokine CCL5 - pharmacology | Receptors, Chemokine - physiology | Endothelium, Vascular - metabolism | Apolipoproteins E - genetics | Protein Binding | Endothelium, Vascular - pathology | Mice | Receptors, CCR1 | Arteriosclerosis - pathology | Receptors, CCR2 | Index Medicus
Journal Article
Oral Diseases, ISSN 1354-523X, 11/2011, Volume 17, Issue 8, pp. 801 - 807
OBJECTIVE: Sjogren's syndrome is a chronic autoimmune disorder characterized by progressive lymphocytic infiltration within the salivary and lacrimal glands.... 
Innate immunity | Mouse | Sjögren's syndrome | Sialoadenitis | CELLS | Sjogren's syndrome | DOUBLE-STRANDED-RNA | SIALADENITIS | RECOGNITION | RIG-I | MECHANISMS | sialoadenitis | TOLL-LIKE RECEPTOR-3 | PATHOGENESIS | mouse | innate immunity | AUTOIMMUNE PANCREATITIS | DENTISTRY, ORAL SURGERY & MEDICINE | MICE | Monocyte Chemoattractant Proteins - drug effects | Chemokine CCL11 - analysis | Chemokine CXCL13 - analysis | Dendritic Cells - pathology | Sjogren's Syndrome - immunology | Killer Cells, Natural - pathology | CD4-Positive T-Lymphocytes - pathology | Chemokines, CC - analysis | Chemokine CXCL10 - analysis | Flow Cytometry | Chemokine CXCL10 - drug effects | Chemokine CCL4 - drug effects | Dendritic Cells - drug effects | Female | Chemokines, CXC - analysis | Chemokines, CXC - drug effects | Chemokine CCL4 - analysis | Real-Time Polymerase Chain Reaction | Disease Models, Animal | Chemokines, CC - drug effects | Poly I-C - pharmacology | Sjogren's Syndrome - pathology | Immunity, Innate - drug effects | Submandibular Gland Diseases - pathology | Submandibular Gland Diseases - immunology | Toll-Like Receptor 3 - agonists | Chemokine CCL7 - analysis | Mice, Inbred NZB | Chemokine CCL3 - analysis | Chemokine CCL3 - drug effects | Sialadenitis - pathology | Immunity, Innate - immunology | Animals | Chemokine CCL7 - drug effects | Monocyte Chemoattractant Proteins - analysis | Chemokine CCL11 - drug effects | Killer Cells, Natural - drug effects | Mice | Chemokine CXCL13 - drug effects | CD4-Positive T-Lymphocytes - drug effects | Chemokine CCL2 - analysis | Chemokine CCL2 - drug effects | Sialadenitis - immunology | Immunohistochemistry | Dendritic cells | Analysis | Genes | Disease susceptibility | T cells | Gene expression | Dentistry
Journal Article
Journal Article
Diabetes Care, ISSN 0149-5992, 05/2010, Volume 33, Issue 5, pp. 1103 - 1108
OBJECTIVE - In view of the previously described anti-inflammatory effects of insulin, we investigated the potential suppressive effect of insulin on plasma... 
MIGRATION | INFLAMMATION | DISEASE | ENDOCRINOLOGY & METABOLISM | MONONUCLEAR-CELLS | ATHEROSCLEROSIS | SUBSETS | DEFICIENT MICE | KAPPA-B | EXPRESSION | ADIPOSE-TISSUE | Receptors, CCR2 - genetics | Interleukin-8 - genetics | Chemokines - blood | Obesity - immunology | Receptors, Chemokine - blood | Humans | Middle Aged | Chemokine CCL4 - genetics | Receptors, CCR5 - genetics | Insulin - blood | Obesity - blood | Inflammation - blood | Chemokine CCL5 - blood | Hypoglycemic Agents - blood | Chemokine CXCL12 - genetics | Chemokine CX3CL1 - blood | Hypoglycemic Agents - administration & dosage | Inflammation - drug therapy | Diabetes Mellitus, Type 2 - immunology | Gene Expression - immunology | Adult | Receptors, CXCR4 - genetics | Chemokine CCL4 - blood | Interleukin-8 - blood | Receptors, Chemokine - genetics | Immunosuppressive Agents - administration & dosage | Receptors, CCR5 - blood | Chemokine CCL11 - genetics | Chemokine CX3CL1 - genetics | Insulin - administration & dosage | Inflammation - immunology | Chemokines - genetics | Diabetes Mellitus, Type 2 - blood | Chemokine CCL5 - genetics | Chemokine CXCL12 - blood | Receptors, CCR2 - blood | Infusions, Intravenous | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | CX3C Chemokine Receptor 1 | Chemokine CCL11 - blood | Receptors, CXCR4 - blood | Physiological aspects | Dosage and administration | Insulin | Chemokine receptors | Chemokines | Methods | Diabetes therapy | Plasma | Pathogenesis | Rodents | Mortality | Atherosclerosis | Cardiovascular disease | Insulin resistance | Bone density | Diabetes | Blood | Index Medicus | Original Research
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 02/2006, Volume 65, Issue 2, pp. 209 - 215
Background: Chemokines are involved in leucocyte chemotaxis. Infiltrating leucocytes play an important role of tissue injury in systemic lupus erythematosus... 
RHEUMATOID-ARTHRITIS | PROINFLAMMATORY CYTOKINE | IMMUNE-RESPONSE | IFN-GAMMA | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | GENE-EXPRESSION | PERIPHERAL-BLOOD | TNF-ALPHA | RHEUMATOLOGY | T-CELLS | DISEASE-ACTIVITY | Intercellular Signaling Peptides and Proteins - analysis | Chemokines - blood | Chemokines, CC - blood | Chemokines, CXC - blood | Humans | Middle Aged | Interleukin-10 - blood | Male | Lupus Erythematosus, Systemic - blood | Case-Control Studies | Chemokine CCL5 - analysis | Chemokines, CC - analysis | Intercellular Signaling Peptides and Proteins - blood | Chemokine CCL5 - blood | Interleukin-18 - analysis | Leukocytes, Mononuclear - immunology | Phytohemagglutinins - pharmacology | Lupus Erythematosus, Systemic - immunology | Adult | Female | Chemokines, CXC - analysis | Interleukin-8 - blood | Interleukin-10 - analysis | Chemokine CXCL9 | Acute Disease | Chemokine CCL17 | Interleukin-18 - blood | Cells, Cultured | Chemokine CCL2 - blood | Interleukin-8 - analysis | Chemokines - analysis | Interferon-gamma - analysis | Analysis of Variance | Lipopolysaccharides - pharmacology | T-Lymphocytes - immunology | Chemokine CCL2 - analysis | Interferon-gamma - blood | Physiological aspects | Development and progression | Systemic lupus erythematosus | Interleukin-18 | Analysis | Chemokines | Lupus | Plasma | Cytokines | Pathogenesis | Neutrophils | Roles | Inflammation | Patients | Studies | Leucocytes | Lymphocytes | Rodents | Kidney diseases | Autoimmune diseases | Index Medicus | IL18 | SLEDAI | Extended Report | systemic lupus erythematosus | inflammatory chemokines
Journal Article
2000, Methods in molecular biology, ISBN 9780896037229, Volume 138., xiii, 353
In the past decade research has established the biological importance of chemokines: they play a major role in leukocyte trafficking, in the recruitment of... 
Receptors | Analysis | Chemokines | Immunology | Biomedicine
Book
International Immunology, ISSN 0953-8178, 2000, Volume 12, Issue 9, pp. 1285 - 1292
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 8, pp. 850 - 858
The success of antitumor immune responses depends on the infiltration of solid tumors by effector T cells, a process guided by chemokines. Here we show that in... 
CD26 EXPRESSION | CELLS | CXCL10 | CHEMOKINE ACTIVITY | IN-VIVO | RECEPTOR | IMMUNOLOGY | CD26/DIPEPTIDYL PEPTIDASE-IV | PROTEINS | CANCER | POSTTRANSLATIONAL MODIFICATION | Dipeptidyl Peptidase 4 - metabolism | Immunotherapy - methods | Male | Adoptive Transfer | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | Cell Movement - immunology | Flow Cytometry | Lymphocytes - immunology | Neoplasms, Experimental - immunology | Chemokine CXCL10 - immunology | Neoplasms, Experimental - genetics | Female | Sitagliptin Phosphate | Dipeptidyl Peptidase 4 - immunology | Chemokines - immunology | Lymphocytes - metabolism | Receptors, CXCR3 - metabolism | Mice, Inbred C57BL | Neoplasms, Experimental - therapy | Dipeptidyl Peptidase 4 - genetics | Mice, Transgenic | Mice, Knockout | Triazoles - pharmacology | Cell Movement - drug effects | Animals | Receptors, CXCR3 - immunology | Cell Line, Tumor | Chemokines - metabolism | Mice, Inbred BALB C | Pyrazines - pharmacology | Chemokine CXCL10 - metabolism | Care and treatment | Usage | Immunotherapy | Development and progression | Inflammation | Health aspects | Chemokines | Tumors | Index Medicus | Neoplasms, Experimental/genetics | Immunotherapy/methods | Cell Movement/drug effects | Neoplasms, Experimental/therapy | Lymphocytes/metabolism | Lymphocytes/immunology | Dipeptidyl Peptidase 4/genetics | Life Sciences | Chemokine CXCL10/immunology | Immunology | Pyrazines/pharmacology | Dipeptidyl Peptidase 4/immunology | Dipeptidyl-Peptidase IV Inhibitors/pharmacology | Chemokines/metabolism | Receptors, CXCR3/immunology | Receptors, CXCR3/metabolism | Neoplasms, Experimental/immunology | Triazoles/pharmacology | Cell Movement/immunology | Chemokines/immunology | Dipeptidyl Peptidase 4/metabolism | Chemokine CXCL10/metabolism
Journal Article