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1962, Volume Bd. 8., x, 706
Book
SCIENCE TRANSLATIONAL MEDICINE, ISSN 1946-6234, 07/2014, Volume 6, Issue 247, pp. 247ra100 - 247ra100
Hepatic accumulation of bile acids is central to the pathogenesis of cholestatic liver diseases. Endocrine hormone fibroblast growth factor 19 (FGF19) may... 
MEDICINE, RESEARCH & EXPERIMENTAL | HEPATOCELLULAR-CARCINOMA | HORMONE | INTRAHEPATIC CHOLESTASIS | PRIMARY BILIARY-CIRRHOSIS | FARNESOID-X-RECEPTOR | FIBROBLAST-GROWTH-FACTOR | BILE-ACID SYNTHESIS | MICE | EXPRESSION | CANCER | CELL BIOLOGY | Recombinant Proteins - therapeutic use | Fibroblast Growth Factors - adverse effects | Liver - pathology | Humans | Middle Aged | Fibroblast Growth Factors - genetics | Male | Cholagogues and Choleretics - adverse effects | Cholestenones - blood | Fibroblast Growth Factors - biosynthesis | Cholestasis, Intrahepatic - drug therapy | Healthy Volunteers | RNA, Messenger - metabolism | Cholagogues and Choleretics - therapeutic use | Genetic Variation | Young Adult | Liver - drug effects | Adult | Liver Neoplasms - pathology | Cholestasis, Extrahepatic - pathology | Disease Models, Animal | Fibroblast Growth Factors - therapeutic use | Gene Transfer Techniques | Cholestasis, Intrahepatic - genetics | Double-Blind Method | Liver Neoplasms - genetics | Risk Assessment | Cholestasis, Intrahepatic - pathology | Down-Regulation | Liver - metabolism | Bile Acids and Salts - metabolism | Biomarkers - blood | Cholestasis, Extrahepatic - genetics | Gene Expression Regulation, Enzymologic | Cholagogues and Choleretics - pharmacokinetics | Cholesterol 7-alpha-Hydroxylase - genetics | Cholestasis, Intrahepatic - metabolism | Animals | Fibroblast Growth Factors - pharmacokinetics | Cholesterol 7-alpha-Hydroxylase - metabolism | Liver Neoplasms - metabolism | Mice | Cholestasis, Extrahepatic - metabolism | Australia | Cholestasis, Extrahepatic - drug therapy | Index Medicus
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2009, Volume 51, Issue 2, pp. 237 - 267
Gastroenterology and Hepatology | Primary biliary cirrhosis | Intrahepatic cholestasis of pregnancy | Immunoglobulin G4-associated cholangitis | Overlap syndrome | Cholestatic liver diseases in pregnancy | Primary sclerosing cholangitis | Fatigue | Drug-induced cholestatic liver disease | Pruritus | Genetic cholestatic liver disease | MODIFIED SCORING SYSTEM | DOSE URSODEOXYCHOLIC ACID | BLIND CONTROLLED-TRIAL | ENDOSCOPIC RETROGRADE CHOLANGIOGRAPHY | HEPATITIS OVERLAP SYNDROME | RANDOMIZED-CONTROLLED-TRIALS | PRIMARY BILIARY-CIRRHOSIS | PLACEBO-CONTROLLED TRIAL | GASTROENTEROLOGY & HEPATOLOGY | FAMILIAL INTRAHEPATIC CHOLESTASIS | Osteoporosis - therapy | Liver Cirrhosis, Biliary - therapy | Humans | Infant | Male | Cholangitis - immunology | Osteoporosis - etiology | Cholestasis, Intrahepatic - prevention & control | Cholestasis, Intrahepatic - etiology | Adult | Female | Child | Hepatitis, Autoimmune - therapy | Hepatitis, Autoimmune - diagnosis | Cholangitis - diagnosis | Pregnancy Complications - diagnosis | Cystic Fibrosis - complications | Syndrome | Pregnancy | Liver Cirrhosis, Biliary - diagnosis | Cholangitis, Sclerosing - therapy | Cholestasis, Intrahepatic - diagnosis | Cholangitis, Sclerosing - diagnosis | Cholangitis - therapy | Cholestasis, Intrahepatic - therapy | Immunoglobulin G - metabolism | Pregnancy Complications - therapy | Practice guidelines (Medicine) | Liver cancer | Diagnostic imaging | Phosphatases | Immunoglobulin G | Ulcerative colitis | Index Medicus
Journal Article
Journal Article
Journal of Pediatric Gastroenterology and Nutrition, ISSN 0277-2116, 07/2016, Volume 64, Issue 1, pp. 154 - 168
Journal Article
Gastroenterology, ISSN 0016-5085, 2012, Volume 142, Issue 2, pp. 355 - 365.e4
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 08/2016, Volume 305, pp. 127 - 135
Alpha-naphthylisothiocyanate (ANIT) is a toxicant that is widely used in rodents to model human intrahepatic cholestasis. The aim of the study is to... 
Dioscin | Oatps | Mrp2 | Bsep | ANIT-induced cholestasis | EXTRAHEPATIC CHOLESTASIS | OLIGOPEPTIDE TRANSPORTER PEPT1 | ACUTE-RENAL-FAILURE | INDUCED LIVER-INJURY | NATURAL STEROID SAPONIN | EXPORT PUMP | PHARMACOLOGY & PHARMACY | TOXICOLOGY | INDUCED INTRAHEPATIC CHOLESTASIS | UP-REGULATION | ADAPTIVE RESPONSE | DUBIN-JOHNSON SYNDROME | Diosgenin - pharmacokinetics | Liver - pathology | Rats, Wistar | Male | Cholestasis, Intrahepatic - drug therapy | Hepatocytes - metabolism | Protective Agents - therapeutic use | RNA, Messenger - metabolism | Organic Anion Transporters - metabolism | 1-Naphthylisothiocyanate | Organic Anion Transporters - genetics | ATP-Binding Cassette Transporters - genetics | Liver - drug effects | Protective Agents - pharmacology | ATP-Binding Cassette Transporters - metabolism | Diosgenin - therapeutic use | Diosgenin - analogs & derivatives | Diosgenin - pharmacology | Protective Agents - pharmacokinetics | Cholestasis, Intrahepatic - chemically induced | Cholestasis, Intrahepatic - pathology | Liver - metabolism | Receptors, Cytoplasmic and Nuclear - genetics | Cholestasis, Intrahepatic - metabolism | Animals | Estrone - analogs & derivatives | ATP Binding Cassette Subfamily B Member 11 | Estrone - pharmacokinetics | Receptors, Cytoplasmic and Nuclear - metabolism | Drug resistance in microorganisms | Jaundice, Obstructive | Liver | Cholestasis | Index Medicus | ANIONS | RATS | MASS SPECTROSCOPY | PATHOLOGY | HISTOLOGY | 60 APPLIED LIFE SCIENCES | SALTS | POLYMERASE CHAIN REACTION | POLYMERASES | IN VITRO | LIQUID COLUMN CHROMATOGRAPHY | DRUGS | LIVER CELLS | SODIUM IONS | AMINOTRANSFERASES | BILE | SULFATES | SODIUM | IN VIVO | ESTRONE | POLYPEPTIDES | BILIRUBIN | CHAIN REACTIONS | ALANINES | LIVER | RECEPTORS
Journal Article
PLoS ONE, 09/2013, Volume 8, Issue 9
Background The human SLC25A13 gene encodes citrin, the liver-type mitochondrial aspartate/glutamate carrier isoform 2 (AGC2), and SLC25A13 mutations cause... 
Cholestasis
Journal Article
IUBMB Life, ISSN 1521-6543, 12/2017, Volume 69, Issue 12, pp. 978 - 984
Lipopolysaccharides (LPS) are known to cause cholestasis in sepsis. There is evidence that a defective expression of canalicular aquaporin water channels... 
biliary bile acid excretion | gene transfer | LPS‐induced cholestasis | aquaporin‐1 | bile acid export pump | LPS-induced cholestasis | aquaporin-1 | RAT-LIVER | SALT EXPORT PUMP | BIOCHEMISTRY & MOLECULAR BIOLOGY | TAUROCHOLATE | CELL BIOLOGY | GENE | MEMBRANE CHOLESTEROL | ORGANIC-ANIONS | SECRETION | BILE FORMATION | ESTROGEN-INDUCED CHOLESTASIS | CAVEOLIN-1 | Cholestasis - genetics | Liver - pathology | Rats, Wistar | Cholestasis - therapy | Humans | Hepatocytes - pathology | Male | Hepatocytes - metabolism | Aquaporin 1 - metabolism | Lipopolysaccharides | Sepsis - pathology | Biological Transport | ATP Binding Cassette Subfamily B Member 11 - metabolism | Adenoviridae - genetics | Transgenes | Gene Expression | Genetic Vectors - chemistry | Rheology | Liver - metabolism | Genetic Vectors - metabolism | Rats | Bile Acids and Salts - metabolism | Cholestasis - chemically induced | Cholesterol - metabolism | Sepsis - genetics | Aquaporin 1 - genetics | Cholestasis - pathology | Animals | Sepsis - chemically induced | Sepsis - therapy | Adenoviridae - metabolism | ATP Binding Cassette Subfamily B Member 11 - genetics | Genetic Therapy - methods | Jaundice, Obstructive | Aquaporins | Adenoviruses | Genetic research | Mitogens | Cholestasis | Deoxycholic acid | Excretion | Bile acids | Liver | Gallbladder diseases | Immunoblotting | Cholesterol | Acids | Hepatocytes | Rodents | Plasma membranes | Sepsis | Bile | Index Medicus
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 149, Issue 3, pp. 649 - 659
Background & Aims There are no effective and safe treatments for chronic hepatitis C virus (HCV) infection of patients who have advanced liver disease. Methods... 
Gastroenterology and Hepatology | Liver Transplantation | Decompensated Cirrhosis | Hepatitis C Virus Infection | Fibrosing Cholestatic Hepatitis | C INFECTION | TRANSPLANTATION PATIENTS | RECIPIENTS | INTERFERON | THERAPY | ADEFOVIR DIPIVOXIL | CIRRHOSIS | GENOTYPE 1 INFECTION | OUTCOMES | GASTROENTEROLOGY & HEPATOLOGY | United States | Humans | Middle Aged | Fluorenes - therapeutic use | Liver Cirrhosis - mortality | Hepacivirus - genetics | Male | Cholestasis, Intrahepatic - drug therapy | Hepatitis C, Chronic - complications | Hepatitis C, Chronic - mortality | Time Factors | Female | Fluorenes - adverse effects | Uridine Monophosphate - adverse effects | Benzimidazoles - adverse effects | Drug Therapy, Combination | Cholestasis, Intrahepatic - virology | Benzimidazoles - therapeutic use | Uridine Monophosphate - therapeutic use | Hepacivirus - drug effects | Liver Cirrhosis - drug therapy | Liver Cirrhosis - diagnosis | Antiviral Agents - therapeutic use | Ribavirin - therapeutic use | Genotype | Treatment Outcome | Hepatitis C, Chronic - diagnosis | Hepatitis C, Chronic - drug therapy | Disease Progression | Cholestasis, Intrahepatic - mortality | Hepacivirus - enzymology | Liver Cirrhosis - virology | Cholestasis, Intrahepatic - diagnosis | Ribavirin - adverse effects | Antiviral Agents - adverse effects | Uridine Monophosphate - analogs & derivatives | Drug Combinations | Care and treatment | Liver diseases | Hepatitis C virus | Hepatitis C | Health aspects | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Pediatric Gastroenterology and Nutrition, ISSN 0277-2116, 01/2011, Volume 52, Issue 1, pp. 73 - 83
Journal Article