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International Journal of Molecular Sciences, ISSN 1661-6596, 09/2017, Volume 18, Issue 9, p. 1842
As in humans, osteoarthritis (OA) causes considerable economic loss to the equine industry. New hopes for cartilage repair have emerged with the... 
Col1a1 | Chondrocyte | Tissue engineering | Dedifferentiation | Hypoxia | Matrix-associated autologous chondrocyte implantation (MACI) | HtrA1 | BMP-2 | Equine model | Type II collagen | SiRNA | CARTILAGE REPAIR | OSTEOARTHRITIC CHONDROCYTES | matrix-associated autologous chondrocyte implantation (MACI) | hypoxia | tissue engineering | BONE MORPHOGENETIC PROTEIN-2 | BIOCHEMISTRY & MOLECULAR BIOLOGY | SERINE-PROTEASE HTRA1 | dedifferentiation | siRNA | COLLAGEN SPONGE SCAFFOLDS | HUMAN ARTICULAR CHONDROCYTES | CHEMISTRY, MULTIDISCIPLINARY | MESENCHYMAL STEM-CELLS | CHONDROGENIC EXPRESSION | type II collagen | equine model | chondrocyte | II COLLAGEN | TERM-FOLLOW-UP | Bone Morphogenetic Protein 2 - pharmacology | RNA, Small Interfering - genetics | Chondrocytes - cytology | Collagen Type I - metabolism | Cartilage, Articular - cytology | Collagen Type III - metabolism | Extracellular Matrix - metabolism | Cell Differentiation - genetics | Chondrocytes - drug effects | Phenotype | Animals | RNA Interference | Cartilage, Articular - metabolism | Cell Differentiation - drug effects | Bone Morphogenetic Protein 2 - metabolism | Biomarkers | Horses | Cell Culture Techniques | Cell Hypoxia - genetics | Chondrocytes - metabolism | Tissue Engineering | Cell culture | Therapy | Collagen (type I) | Clinical trials | Cartilage | Biomedical materials | Bone morphogenetic proteins | Extracellular matrix | Biocompatibility | Medical research | Bone morphogenetic protein 2 | RNA-mediated interference | Interference | Implantation | Data processing | Ribonucleic acids | Collagen | Chondrocytes | Autologous chondrocyte implantation | Osteoarthritis | Three dimensional models | Cartilage diseases | Index Medicus | Life Sciences
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 11/2010, Volume 402, Issue 1, pp. 23 - 29
The MAPK/ERK pathway is involved in IL-1b-induced cyclooxygenase (COX-2) expression and prostaglandin E2 (PGE2) production; two factors that play important... 
Chondrocytes
Journal Article
Science, ISSN 0036-8075, 5/2012, Volume 336, Issue 6082, pp. 717 - 721
Osteoarthritis (OA) is a degenerative joint disease that involves the destruction of articular cartilage and eventually leads to disability. Molecules that... 
Cartilage | Molecules | REPORTS | Chondrocytes | Collagens | Stem cells | Lead | Arthritis | Chondrogenesis | Osteoarthritis | Vehicles | PATHOGENESIS | GENE | ARTICULAR-CARTILAGE | MULTIDISCIPLINARY SCIENCES | FILAMIN | OSTEOARTHRITIS | BONE | TRANSCRIPTION FACTOR | EXPRESSION | CHONDROGENESIS | CHONDROCYTE DIFFERENTIATION | Anilides - therapeutic use | Chondrocytes - cytology | Phthalic Acids - chemistry | Humans | Anilides - chemistry | Structure-Activity Relationship | Osteoarthritis - drug therapy | Osteoarthritis - physiopathology | Chondrocytes - drug effects | Mesenchymal Stromal Cells - cytology | Cell Nucleus - metabolism | Chondrocytes - physiology | Cattle | Microfilament Proteins - metabolism | Osteoarthritis - pathology | Phthalic Acids - pharmacology | Contractile Proteins - metabolism | Chondrocytes - metabolism | Mesenchymal Stromal Cells - physiology | Core Binding Factor beta Subunit - metabolism | Disease Models, Animal | Mesenchymal Stromal Cells - drug effects | Phthalic Acids - therapeutic use | Core Binding Factor Alpha 2 Subunit - metabolism | Cartilage, Articular - cytology | Filamins | Phthalic Acids - administration & dosage | Regeneration | Animals | High-Throughput Screening Assays | Anilides - administration & dosage | Small Molecule Libraries | Anilides - pharmacology | Mice | Care and treatment | Physiological aspects | Transplantation | Methods | Molecular biology | Index Medicus | Animal models | Biomedical materials | Effectiveness | Breakdown | Biocompatibility | Articular | Adults
Journal Article
Development (Cambridge), ISSN 0950-1991, 01/2017, Volume 144, Issue 2, pp. 221 - 234
Fractures heal predominantly through the process of endochondral ossification. The classic model of endochondral ossification holds that chondrocytes mature to... 
Pluripotency programs | Fracture repair | Endochondral ossification | Chondrocyte transformation | OSTEOBLAST DIFFERENTIATION | MARROW | DEVELOPMENTAL BIOLOGY | SIGNALING CENTER | MESENCHYMAL STEM-CELLS | CHONDROCYTE DIFFERENTIATION | CRE ACTIVITY | OCT4 EXPRESSION | IN-VIVO | HYPERTROPHIC CHONDROCYTES | SOX9 | Human Umbilical Vein Endothelial Cells | Bony Callus - growth & development | Chondrocytes - cytology | Osteogenesis - physiology | Humans | Male | Cell Transdifferentiation - genetics | Chondrocytes - physiology | Cartilage - cytology | Fracture Healing - physiology | Cartilage - physiology | Osteoblasts - cytology | Bone and Bones - cytology | Bone and Bones - physiology | Neovascularization, Physiologic - genetics | Mice, Inbred C57BL | Osteoblasts - physiology | Pluripotent Stem Cells - physiology | Cells, Cultured | Up-Regulation - genetics | Mice, Knockout | Chondrogenesis - physiology | Neovascularization, Physiologic - physiology | Animals | Mice | Fracture Healing - genetics | Bony Callus - metabolism | Callus | Transformation | Therapeutic applications | Oct-4 protein | Cell division | Bone healing | Osteoblasts | Endothelial cells | Ossification | Cartilage | Growth plate | Regeneration | Fractures | Molecular modelling | Rodents | Chondrocytes | Bone (endochondral) | Pluripotency | Hypertrophy | Apoptosis | Index Medicus | Stem Cells and Regeneration
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 658 - 10
Journal Article
Acta Biomaterialia, ISSN 1742-7061, 2011, Volume 7, Issue 1, pp. 234 - 243
Journal Article
Scientific reports, ISSN 2045-2322, 04/2019, Volume 9, Issue 1, pp. 5975 - 1
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. 
Chondrocytes
Journal Article
Biomaterials, ISSN 0142-9612, 02/2014, Volume 35, Issue 7, pp. 2207 - 2217
We developed an injectable hydrogel system to evaluate the effect of hydrogel stiffness on chondrocyte cellular functions in a three-dimensional (3D)... 
Cartilage | Injectable | Chondrocyte | Stiffness | Hydrogel
Journal Article
The American Journal of Sports Medicine, ISSN 0363-5465, 02/2008, Volume 36, Issue 2, pp. 235 - 246
Journal Article
PLoS ONE, 08/2013, Volume 8, Issue 8
Multiple osteochondromas (MO) is an inherited skeletal disorder, and the molecular mechanism of MO remains elusive. Exome sequencing has high chromosomal... 
Chondrocytes
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 09/2017, Volume 21, Issue 9, pp. 1835 - 1847
Articular chondrocytes reside in lacunae distributed in cartilage responsible for the remodelling of the tissue with limited ability of damage repairing. The... 
COL II | collagen type I | COL | β‐catenin | chondrocyte activity | passaged chondrocytes | Cytl‐1 | viable cells | Sox9 | salvianolic acid B | collagen type | β-catenin | Cytl-1 | collagen type II (COL II) | collagen type I (COL I) | MEDICINE, RESEARCH & EXPERIMENTAL | catenin | MESENCHYMAL CELLS | FOLLOW-UP | BETA-CATENIN | BONE-DEVELOPMENT | MILTIORRHIZA | CARTILAGE | CELL BIOLOGY | IN-VITRO | PATHWAY | GROWTH | ARTICULAR CHONDROCYTES | SOX9 Transcription Factor - metabolism | Cell Survival - drug effects | Rabbits | Transcription, Genetic - drug effects | Chondrocytes - cytology | Humans | Cells, Cultured | Cell Survival - genetics | Benzofurans - pharmacology | Aggrecans - metabolism | Membrane Potential, Mitochondrial - drug effects | Aggrecans - genetics | Collagen Type II - genetics | Cell Shape - drug effects | Collagen Type II - metabolism | Gene Expression Regulation - drug effects | Chondrocytes - drug effects | Animals | Chondrocytes - ultrastructure | Nucleic Acids - biosynthesis | Cell Proliferation - drug effects | Receptors, Cytokine - metabolism | SOX9 Transcription Factor - genetics | Chondrocytes - metabolism | Genetic research | Gene expression | Collagen | Analysis | Genes | Cell culture | Wnt protein | Transcription | Sox9 protein | Staining | Paracrine signalling | Confocal microscopy | Confocal | Foaming agents | Western blotting | Proteins | Cartilage | Genotype & phenotype | Mitochondria | Membrane potential | Lesions | Repair | Cytokines | Implantation | Pharmacology | Maintenance | Chemical compounds | Polymerase chain reaction | Salvia miltiorrhiza | Acids | Lymphocytes B | Microscopy | Chondrocytes | In vitro methods and tests | Viability | Scanning microscopy | Index Medicus | Original
Journal Article
Journal Article
Osteoarthritis and Cartilage, ISSN 1063-4584, 2015, Volume 24, Issue 4, pp. 752 - 762
Journal Article