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07/2020
... to summarize and compare several models of chromatin fiber folding to form mitotic chromosomes and discusses them in the light of the novel findings. Functional genomics... 
Genetic research | Chromatin
Newsletter
Journal of plant research, ISSN 0918-9440, 07/2020, Volume 133, Issue 4, pp. 479 - 488
.... This review discusses recent advances in the fields of three-dimensional chromosome folding and nuclear compartmentalization and describes a novel silencing mechanism... 
ARABIDOPSIS-THALIANA | CHROMATIN | Arabidopsis | RIBOSOMAL-RNA GENES | PLANT SCIENCES | PHASE-SEPARATION | NUCLEOLUS | INTERPHASE CHROMOSOMES | REFERENCE GENOME | Hi-C | HETEROCHROMATIN | ARCHITECTURE | Chromosome conformation capture | Nuclear compartments | LONG-RANGE INTERACTIONS
Journal Article
The Journal of cell biology, ISSN 0021-9525, 07/2020, Volume 219, Issue 7
Membrane integrity at the endoplasmic reticulum (ER) is tightly regulated, and its disturbance is implicated in metabolic diseases. Using an engineered sensor... 
Yeasts | Lipid composition | Chromatin | Membranes | Yeast | Immunoprecipitation | Transcription | Homeostasis | Lipids | Helices | Gene expression | Lipid bilayers | Proteins | Protein folding | Lipid metabolism | Sensors | Endoplasmic reticulum | Potassium | Metabolic disorders | Integrity
Journal Article
Molecular & cellular oncology, ISSN 2372-3556, Volume ahead-of-print, Issue ahead-of-print, p. 1776086
.... Using stochastic optical reconstruction microscopy optimized for pathological tissue (PathSTORM), we uncovered a gradual decompaction of higher-order chromatin folding through progressive stages of carcinogenesis... 
CUT&RUN | diagnostics | PathSTORM | chromatin | oncogenesis
Journal Article
Developmental cell, ISSN 1534-5807, 06/2020, Volume 53, Issue 5, pp. 561 - 576.e9
Regional specification is critical for skin development, regeneration, and evolution. The contribution of epigenetics in this process remains unknown. Here,... 
feather | development | chromatin looping | enhancers | SATB2 | scale | higher-order | evolution | CTCF | KLF4 | beta-keratin | epigenetics | TRANSCRIPTION FACTORS | READ ALIGNMENT | CHROMOSOMAL INTERACTIONS | PROTOCADHERIN-ALPHA | DEVELOPMENTAL BIOLOGY | DIFFERENTIATION | CONFORMATION | PROMOTER | EXPRESSION | BETA-KERATINS | CHROMATIN ARCHITECTURE | CELL BIOLOGY
Journal Article
Frontiers in microbiology, ISSN 1664-302X, 06/2020, Volume 11
...–40-nm globular structures, suggesting the occurrence of higher-order chromosomal folding... 
higher-order chromosome structure | nucleoid associated proteins (NAPs) | histone | chromatin | structural maintenance of chromosomes (SMC) proteins | archaea
Journal Article
Journal of human genetics, ISSN 1434-5161, 06/2020, Volume 65, Issue 6, pp. 497 - 511
In the 20th century, our familiar structure of DNA was the double helix. Due to technical limitations, we do not have a good way to understand the finer... 
TRANSCRIPTION FACTORS | ANALYSIS REVEALS | NUCLEAR-ORGANIZATION | LONG-RANGE | CHROMATIN DOMAINS | SUPER-ENHANCERS | COPY-NUMBER | INSULATED NEIGHBORHOODS | ANDROGEN-RECEPTOR | GENETICS & HEREDITY | PHASE-I
Journal Article
Genetics (Austin), ISSN 0016-6731, 06/2020, Volume 215, Issue 2, pp. 407 - 420
Mediator is an essential, multisubunit complex that functions as a transcriptional coactivator in yeast and other eukaryotic organisms. Mediator has four... 
TRANSCRIPTION FACTOR-BINDING | COMPLEX | ACTIVATION | chromatin | YEAST | TATA-BINDING PROTEIN | gene regulation | HO EXPRESSION | GENETICS & HEREDITY | GENE-EXPRESSION | CELL-CYCLE | mediator | PROMOTER | coactivator | Binding | Yeasts | Phosphorylation | Transcription factors | Yeast | Genes | Gene regulation | Modules | Activation | RNA polymerase | Kinases | HO gene | Tails | Constraining | Recruitment | Plasmids | Cell cycle | Mutation
Journal Article
Biophysics reports, ISSN 2364-3439, 06/2020, Volume 6, Issue 2-3, pp. 33 - 48
Mechanical force regulates a variety of cellular functions through inducing modulations in nuclear chromatin structures and epigenetic landscapes (outside in).... 
Regulations | Chromatin | Phenotypes | Fluorescence | Functionals | Cells (biology) | Epigenetics | Cytoskeleton | Extracellular matrix | Mechanotransduction | Fluorescence resonance energy transfer | Biosensors | Energy transfer | Cellular structure
Journal Article
Nature chemistry, ISSN 1755-4330, 06/2020, Volume 12, Issue 6, pp. 520 - 520
Elucidating the physiological binding partners of histone post-translational modifications (hPTMs) is key to understanding fundamental epigenetic regulatory... 
PROTEOMICS APPROACH | SPLIT INTEIN | PRC2 | GENE | PROTEIN-PROTEIN INTERACTIONS | PHD FINGER | LYSINE-4 METHYLATION | IDENTIFICATION | HISTONE H3K4ME3 | BINDING | CHEMISTRY, MULTIDISCIPLINARY | Proteins | Translation | Chromatin | Semisynthesis | Proteomics | Post-translation | Epigenetics | Histones | Crosslinking | Mutation
Journal Article
Current opinion in cell biology, ISSN 0955-0674, 06/2020, Volume 64, pp. 105 - 111
... in vivo dynamics of genome folding, and provide mechanistic perspectives that identify further 3D genome players by integrating multiomics information... 
Single-cell biology | Long-range chromatin contacts | Genome | Imaging | 3D topology
Journal Article
Journal Article
Nature neuroscience, ISSN 1097-6256, 05/2020, Volume 23, Issue 6, pp. 707 - 707
Neuronal activation induces rapid transcription of immediate early genes (IEGs) and longer-term chromatin remodeling around secondary response genes (SRGs).... 
IMMEDIATE-EARLY GENE | ACTIVATION | PROTEIN | C-FOS | ANNOTATION | QUANTIFICATION | TRANSCRIPTION | ARC/ARG3.1 | GROWTH-FACTOR | CTCF | NEUROSCIENCES | Mental disorders | Genes | Schizophrenia | Stimulation | Activation | mRNA | Genomes | Nucleotides | Gene expression | Chromatin remodeling | Immediate-early proteins | Autism | Enhancers | Brain-derived neurotrophic factor | Transcription activation | Chromosomes | Conformation
Journal Article
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