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TRENDS IN PARASITOLOGY, ISSN 1471-4922, 03/2017, Volume 33, Issue 3, pp. 158 - 161
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 03/2019, Volume 60, Issue 12, pp. 831 - 833
Cladosporin, a secondary metabolite isolated from fungal sources like and was found to exhibit selective nano-molar activity against malarial parasite by... 
Cladosporin | Anti-malarials | Mitsunobu | Total synthesis | TRANSFER-RNA SYNTHETASE | CHEMISTRY, ORGANIC | METABOLITE | Synthesis | Metabolites | Malaria | Physiological aspects | Protein biosynthesis | Carbon monoxide | Alcohols | Organic compounds
Journal Article
Drug Discovery Today, ISSN 1359-6446, 06/2018, Volume 23, Issue 6, pp. 1233 - 1240
Malaria remains a major infectious disease and, despite incidence reduction, it threatens resurgence in drug-resistant forms. Antimalarial drugs remain the... 
COMPLEX | BENZOXABOROLES | INHIBITION | PROTEIN TRANSLATION | STRUCTURAL BASIS | TOXOPLASMOSIS | SPECTROPHOTOMETRIC ASSAY | CRYSTAL-STRUCTURES | PHARMACOLOGY & PHARMACY | CLADOSPORIN | HALOFUGINONE | Drugs | Plasmodium falciparum | Malaria | Communicable diseases | Antimalarials | Genetic engineering | Drug resistance | Aminoacyl-tRNA synthetases | Transfer RNA
Journal Article
Synlett, ISSN 0936-5214, 06/2017, Volume 28, Issue 10, pp. 1219 - 1223
Abstract β-(2-Pyridyl) ketones are a unique class of heterocycles with valuable physicochemical properties and emerging relevance as pharmacophores. Herein we... 
letter | β-(2-pyridyl) propanone | malaria | acylation | small-molecule natural-product analogues | beta-(2-pyridyl) propanone | BASES | DRUG DISCOVERY | CHEMISTRY, ORGANIC | HARD | CYCLIZATIONS | CHEMISTRY | SOFT ACIDS | CLADOSPORIN | METABOLITE | TOOL
Journal Article
Proteins: Structure, Function, and Bioinformatics, ISSN 0887-3585, 09/2019, Volume 87, Issue 9, pp. 730 - 737
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 01/2016, Volume 57, Issue 1, pp. 53 - 55
Journal Article
Angewandte Chemie, ISSN 0044-8249, 01/2016, Volume 128, Issue 2, pp. 674 - 678
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 09/2013, Volume 54, Issue 38, pp. 5185 - 5187
A highly stereoselective total synthesis of isocladosorpin is described. The key steps involved in this synthesis are oxa-Michael reaction, asymmetric... 
Isocladosorpin | Oxa-Michael reaction | Alder–Rickerts reaction | Asymmetric propargylation | Alder-Rickerts reaction | MICROORGANISMS | METABOLIC PRODUCTS | CYCLOHEXADIENES | CHEMISTRY, ORGANIC | CLADOSPORIN | Synthesis | Organic compounds | Asymmetry | Tetrahedrons | Synthesis (chemistry)
Journal Article
Journal Article
Natural Product Communications, ISSN 1934-578X, 2016, Volume 11, Issue 10, pp. 1595 - 1600
Natural antifungal agents are generally broad-spectrum compounds with low mammalian and environmental toxicity. Cladosporin is a naturally occurring fungal... 
Antimalarial | Cladosporin | Herbicides | Plasmodium falciparum | Antifungal | Lysyl-tRNA Synthetase | Cladosporium cladosporioides | METABOLITES | CHEMISTRY, MEDICINAL | FUNGUS | FOOD SCIENCE & TECHNOLOGY | STEREOCHEMISTRY | TRANSFER-RNA SYNTHETASE | STRUCTURAL BASIS | PLASMODIUM-FALCIPARUM | FATTY-ACID | ISOCLADOSPORIN | POLYKETIDE BIOSYNTHESIS | DERIVATIVES
Journal Article
Marine Drugs, ISSN 1660-3397, 06/2017, Volume 15, Issue 6, p. 191
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 2010, Volume 183, Issue 1, pp. 113 - 124
Journal Article
Bioengineered, ISSN 2165-5979, 04/2016, Volume 7, Issue 2, pp. 60 - 64
Journal Article
MSPHERE, ISSN 2379-5042, 07/2017, Volume 2, Issue 4, p. e00340-17
Leishmania donovani is a protozoan parasite that causes visceral leishmaniasis. Increasing resistance and severe side effects of existing drugs have led to the... 
genetic validation | DOMAIN | RECOGNITION | MITOCHONDRIAL | Leishmania donovani | STAGE | drug targets | MICROBIOLOGY | TRANSLATION | lysyl-tRNA synthetase | INHIBITION | CLASS-I | CHEMOKINE | CLADOSPORIN | RESOURCE
Journal Article