X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (526) 526
claudin-5 (468) 468
animals (466) 466
humans (316) 316
permeability (310) 310
blood-brain barrier (271) 271
male (267) 267
claudin-5 - metabolism (256) 256
mice (230) 230
neurosciences (225) 225
expression (219) 219
occludin (197) 197
rats (196) 196
proteins (190) 190
tight junctions - metabolism (190) 190
membrane proteins - metabolism (182) 182
tight junctions (178) 178
tight junction (168) 168
female (158) 158
blood-brain barrier - metabolism (155) 155
cell biology (146) 146
blood-brain-barrier (140) 140
endothelial cells - metabolism (138) 138
cells, cultured (124) 124
endothelium (124) 124
blood-brain barrier - drug effects (120) 120
endothelial-cells (116) 116
claudin-5 - genetics (110) 110
analysis (101) 101
blood–brain barrier (99) 99
disease models, animal (96) 96
brain (92) 92
immunohistochemistry (92) 92
rats, sprague-dawley (90) 90
occludin - metabolism (89) 89
biochemistry & molecular biology (88) 88
mice, inbred c57bl (87) 87
membrane proteins - genetics (84) 84
article (82) 82
endothelial cells - drug effects (82) 82
neurology (82) 82
cells (81) 81
zonula occludens-1 protein (80) 80
gene expression (79) 79
zonula occludens-1 protein - metabolism (79) 79
endothelial cells (77) 77
in-vitro (71) 71
tight junctions - drug effects (71) 71
blood-brain barrier - pathology (70) 70
brain - metabolism (69) 69
inflammation (69) 69
research (66) 66
cell line (63) 63
rodents (63) 63
pathology (60) 60
activation (58) 58
middle aged (58) 58
phosphoproteins - metabolism (58) 58
rats, wistar (58) 58
rna, messenger - metabolism (58) 58
tight junction proteins (58) 58
claudin (57) 57
blotting, western (56) 56
physiological aspects (56) 56
adult (55) 55
claudin-1 (55) 55
endothelium, vascular - metabolism (55) 55
time factors (54) 54
phosphorylation (53) 53
apoptosis (51) 51
capillary permeability - drug effects (50) 50
multidisciplinary sciences (50) 50
cadherins - metabolism (49) 49
disruption (49) 49
biomedicine (48) 48
pharmacology & pharmacy (48) 48
angiogenesis (47) 47
matrix metalloproteinase 9 - metabolism (47) 47
aged (46) 46
claudins (45) 45
claudins - metabolism (45) 45
electric impedance (45) 45
research article (45) 45
blood-brain barrier - physiology (44) 44
clinical neurology (44) 44
stroke (44) 44
ischemia (42) 42
oncology (42) 42
original (42) 42
oxidative stress (42) 42
physiology (42) 42
zo-1 (42) 42
antigens, cd - metabolism (40) 40
capillary permeability - physiology (40) 40
endothelial cells - cytology (40) 40
barrier (39) 39
brain - blood supply (39) 39
hematology (39) 39
immunology (39) 39
blood-brain barrier - physiopathology (38) 38
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 11/2017, Volume 363, Issue 2, pp. 275 - 283
A current bottleneck in the development of central nervous system (CNS) drugs is the lack of drug delivery systems targeting the CNS. The intercellular space... 
PHARMACOLOGY & PHARMACY | Tight Junctions - metabolism | Humans | Claudin-5 - metabolism | Male | Permeability | Blood-Brain Barrier - metabolism | Claudin-5 - chemistry | Extracellular Space - metabolism | Animals | Cell Line, Tumor | Protein Domains | Female | Claudin-5 - immunology | Mice | Antibodies, Monoclonal - immunology
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 08/2015, Volume 464, Issue 1, pp. 118 - 125
Journal Article
Cellular Microbiology, ISSN 1462-5814, 10/2018, Volume 20, Issue 10, pp. e12862 - n/a
Streptococcus suis serotype 2 (SS2) is a zoonotic agent that causes meningitis in humans and pigs. However, the mechanism whereby SS2 crosses the... 
blood–brain barrier | serine/threonine protein kinase | ubiquitination | Streptococcus suis | serotype 2 | claudin‐5 | E3 ubiquitin ligase HECTD1 | Streptococcus suis serotype 2 | claudin-5 | blood-brain barrier | serine | TRANSLOCATION | TRAVERSAL | PHOSPHATASE | MICROVASCULAR ENDOTHELIAL-CELLS | ESCHERICHIA-COLI INVASION | MICROBIOLOGY | MECHANISMS | IDENTIFICATION | VIRULENCE | CELL BIOLOGY | IN-VITRO | threonine protein kinase | EXPRESSION | Meningitis, Bacterial - microbiology | Virulence Factors - genetics | Claudin-5 - metabolism | Ubiquitin-Protein Ligases - metabolism | Claudin-5 - genetics | Meningitis, Bacterial - pathology | Blood-Brain Barrier - microbiology | Streptococcus suis - pathogenicity | Animals | Receptor Protein-Tyrosine Kinases - genetics | Streptococcus suis - genetics | Virulence - genetics | Swine | DNA Transposable Elements - genetics | Claudin-5 - antagonists & inhibitors | Mice | Mice, Inbred BALB C | Ubiquitination - genetics | Ubiquitin | Transposons | RNA | Ligases | Proteolysis | Analysis | Protein kinases | Brain | Threonine | Immunocytochemistry | Virulence | Antibodies | mRNA | Infections | Kinases | Blood | Endothelium | Degradation | Proteins | Ubiquitination | Streptococcus | Mutagenesis | Blood-brain barrier | Virulence factors | Protein folding | Barriers | Meningitis | Protein-serine/threonine kinase | Microvasculature | Ubiquitin-protein ligase
Journal Article
Journal Article
Nature Neuroscience, ISSN 1097-6256, 12/2017, Volume 20, Issue 12, pp. 1752 - 1760
Journal Article
Neuroscience Letters, ISSN 0304-3940, 2018, p. 133664
The blood-brain barrier (BBB) is a dynamic interface between the peripheral blood supply and the cerebral parenchyma, controlling the transport of material to... 
Schizophrenia | Claudin-5 | Depression | Tight junction | Endothelial cell | Autism spectrum disorder
Journal Article
Annals of the New York Academy of Sciences, ISSN 0077-8923, 06/2017, Volume 1397, Issue 1, pp. 143 - 156
Journal Article
Oncotarget, ISSN 1949-2553, 12/2018, Volume 9, Issue 101, pp. 37564 - 37580
Glioblastomas are highly aggressive brain tumors. Various pathways are involved in gliomagenesis, among which the Wingless (Wnt) signaling. Dickkopf... 
Glioblastomas | TLR-4 | Dkk-3 | Wnt | claudin-5
Journal Article
Journal Article
Neuroscience, ISSN 0306-4522, 09/2015, Volume 304, pp. 355 - 367
The blood-brain barrier (BBB) is formed by the endothelial cells with specialized tight junctions (TJs) lining the blood vessels and astroglial endfeet... 
eNOS | Zonula occludens-1 | Claudin-5 | Vasogenic edema | Status epilepticus | Occludin
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 10/2014, Volume 72, Issue 7, pp. 1417 - 1432
Clostridium perfringens enterotoxin (CPE) binds to distinct claudins (Clds), which regulate paracellular barrier functions in endo- and epithelia. The... 
Protein–protein interactions | Mutagenesis | Tight junctions | Molecular modeling | Drug delivery system | Membrane proteins | Structure–function study | Structure-function study | Protein-protein interactions | TARGET | PROTEIN | MECHANISM | DETERMINANTS | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BARRIER | CANCER | EXTRACELLULAR LOOP | CELL BIOLOGY | TIGHT-JUNCTION | PORE-FORMING TOXINS | Humans | Claudin-5 - metabolism | Amino Acids - chemistry | Molecular Sequence Data | Claudin-1 - chemistry | Amino Acids - genetics | Amino Acids - metabolism | Claudin-5 - chemistry | Claudin-1 - metabolism | HEK293 Cells | Clostridium perfringens - metabolism | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Mutagenesis, Site-Directed | Mutant Proteins - genetics | Models, Molecular | Claudin-5 - genetics | Mutant Proteins - metabolism | Binding Sites - genetics | Sequence Homology, Amino Acid | Microscopy, Confocal | Enterotoxins - genetics | Animals | Clostridium perfringens - genetics | Mutant Proteins - chemistry | Claudin-1 - genetics | Enterotoxins - metabolism | Protein Binding | Luminescent Proteins - genetics | Mice | Enterotoxins - chemistry | Mutation | Luminescent Proteins - metabolism | Drugs | Drug delivery systems | Analysis | Physiological aspects | Chemical properties | Vehicles | Proteins | Membranes | Toxins | Binding sites | Index Medicus
Journal Article
Journal of Cerebral Blood Flow and Metabolism, ISSN 0271-678X, 2018, p. 271678X18817512
Inflammation-induced blood-brain barrier (BBB) dysfunction and microvascular leakage are associated with a host of neurological disorders. The tight junction... 
blood–brain barrier dysfunction | endothelial IR signaling | AKT2 | FOXO1 | claudin-5
Journal Article
Journal Article