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The New England journal of medicine, ISSN 1533-4406, 2011, Volume 364, Issue 23, pp. 2227 - 2234
Journal Article
Journal Article
Journal Article
Cell metabolism, ISSN 1550-4131, 2013, Volume 18, Issue 6, pp. 831 - 843
... elevated phospho-PKR and eIF2α-P levels. Whether and how PKR and eIF2α-P participate in defective brain insulin signaling and cognitive impairment in AD are unknown. We report that β... 
TYROSINE KINASE-ACTIVITY | UNFOLDED PROTEIN RESPONSE | INTRANASAL INSULIN | INSULIN-RESISTANCE | MOUSE MODEL | ENDOCRINOLOGY & METABOLISM | COGNITIVE IMPAIRMENT | NECROSIS-FACTOR-ALPHA | ENDOPLASMIC-RETICULUM STRESS | D-ASPARTATE RECEPTOR | SYNAPTIC PLASTICITY | CELL BIOLOGY | Tumor Necrosis Factor-alpha - metabolism | eIF-2 Kinase - metabolism | Memory Disorders - metabolism | Insulin Receptor Substrate Proteins - metabolism | Receptors, Tumor Necrosis Factor, Type I - metabolism | Alzheimer Disease - pathology | eIF-2 Kinase - deficiency | Brain - metabolism | Receptors, Tumor Necrosis Factor, Type I - deficiency | Synapses - metabolism | Neurons - metabolism | Phosphorylation - drug effects | Neurons - drug effects | Memory Disorders - pathology | Disease Models, Animal | eIF-2 Kinase - genetics | Synapses - drug effects | Amyloid beta-Peptides - toxicity | Haplorhini - metabolism | Receptors, Tumor Necrosis Factor, Type I - genetics | Hypoglycemic Agents - pharmacology | Mice, Knockout | Brain - drug effects | Animals | Signal Transduction - drug effects | Alzheimer Disease - metabolism | Insulin Receptor Substrate Proteins - antagonists & inhibitors | Polymers - toxicity | Polymers - chemistry | Mice | Amyloid beta-Peptides - chemistry | Tumor Necrosis Factor-alpha - antagonists & inhibitors
Journal Article
2006, Studies on neuropsychology, neurology, and cognition, ISBN 9781841694665, x, 319
Mild Cognitive Impairment (MCI) has been identified as an important clinical transition between normal aging and the early stages of Alzheimer's disease (AD... 
physiopathology | Aging | physiology | Cognition disorders | Diagnosis | Cognition disorders in old age | Alzheimer Disease | Alzheimer's disease | Early Diagnosis | Cohort Studies | Gerontology (Ageing) | Cognitive Neuropsychology | Neuropsychology | Cognitive Psychology | Amnesia & Memory Disorders | Cognition disorders in old age - Diagnosis
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