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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2015, Volume 112, Issue 24, pp. 1 - 6
Journal Article
Journal Article
CHEMICAL COMMUNICATIONS, ISSN 1359-7345, 2016, Volume 52, Issue 79, pp. 11752 - 11755
A preferred-handed helicity induced in an optically-inactive poly(phenyleneethynylene)-based foldamer bearing carboxylic acid pendants upon complexation with a... 
SENSE INVERSION | SCREW-SENSE | MAIN-CHAIN | CONFORMATIONAL-CHANGE | CIRCULAR-DICHROISM | PHENYLENE ETHYNYLENE OLIGOMERS | MACROMOLECULAR HELICITY | POLY(PHENYLACETYLENE)S BEARING | CHAIN-LENGTH DEPENDENCE | CHIRAL AMPLIFICATION | CHEMISTRY, MULTIDISCIPLINARY | Complexation | Diamines | Stability | Inversions | Helices | Carboxylic acids | Helicity | Bearing
Journal Article
Journal of Physical Chemistry B, ISSN 1520-6106, 05/2012, Volume 116, Issue 17, pp. 5251 - 5259
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 45, pp. 18392 - 18407
p97 is an essential ATPase associated with various cellular activities (AAA(+)) that functions as a segregase in diverse cellular processes, including the... 
VCP | VALOSIN-CONTAINING PROTEIN | POLYGLUTAMINE DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | cofactor binding | multisystem proteinopathy 1 (MSP1) | VCP/P97 | surface plasmon resonance (SPR) | ATPases associated with diverse cellular activities (AAA) | ENDOPLASMIC-RETICULUM STRESS | conformational change | proteostasis | PAGET-DISEASE | electron microscopy (EM) | p97 | UBIQUITIN CHAINS | STRUCTURAL BASIS | MACHADO-JOSEPH-DISEASE | MOUSE MODEL | ataxin3 | nucleotide regulation | CRYO-EM STRUCTURE | Proteostasis Deficiencies - metabolism | Coenzymes - genetics | Humans | Protein Multimerization | Crystallography, X-Ray | Adenosine Diphosphate - chemistry | Recombinant Fusion Proteins - metabolism | Coenzymes - metabolism | Adenosine Triphosphate - metabolism | Databases, Protein | Distal Myopathies - metabolism | Proteostasis Deficiencies - enzymology | Ataxin-3 - chemistry | Protein Interaction Domains and Motifs | Valosin Containing Protein - chemistry | Ataxin-3 - metabolism | Coenzymes - chemistry | Binding Sites | Peptide Fragments - genetics | Repressor Proteins - metabolism | Binding, Competitive | Microscopy, Electron, Transmission | Peptide Fragments - metabolism | Repressor Proteins - chemistry | Valosin Containing Protein - genetics | Valosin Containing Protein - metabolism | Models, Molecular | Repressor Proteins - genetics | Recombinant Fusion Proteins - chemistry | Protein Interaction Mapping | Distal Myopathies - enzymology | Proteostasis Deficiencies - genetics | Distal Myopathies - genetics | Peptide Fragments - chemistry | Protein Conformation | Adenosine Diphosphate - metabolism | Mutation | Adenosine Triphosphate - chemistry | Amino Acid Substitution | Ataxin-3 - genetics | Molecular Bases of Disease
Journal Article
Journal Article
Journal Article
BBA - Biomembranes, ISSN 0005-2736, 10/2015, Volume 1848, Issue 10, pp. 2065 - 2074
EmrE protein transports positively charged aromatic drugs (xenobiotics) in exchange for two protons and thus provides bacteria resistance to variety of drugs.... 
Molecular dynamics | Small multidrug resistance (SMR) transporter | EmrE | Multidrug transporter | Heterogeneous lipid bilayer | DOMAIN | RECOGNITION | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BILAYERS | CONFORMATIONAL-CHANGES | BIOPHYSICS | LANGEVIN | RESISTANCE | PROVIDES | BINDING | PLASTICITY | Hydrogen | Analysis | Chemical properties
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2019, Volume 116, Issue 13, pp. 6385 - 6390
The mechanism by which gamma-secretase activating protein (GSAP) regulates gamma-secretase activity has not yet been elucidated. Here, we show that knockout of... 
γ-secretase modulation | GSAP | Active-site labeling | Alzheimer’s disease | Conformational change | COMPLEX | APH-1 | ACTIVATING PROTEIN | MULTIDISCIPLINARY SCIENCES | NOTCH | conformational change | gamma-secretase modulation | PEN-2 | INHIBITORS | Alzheimer's disease | active-site labeling | PRESENILIN-1 | Proteins | Crosslinking | Presenilin 1 | Secretase | Biological Sciences
Journal Article