2008, 2nd ed., Drugs and the pharmaceutical sciences, ISBN 9781420044355, Volume 183-184., 2 v.
Because of the slow and costly process of developing new blockbuster drugs, pharmaceutical scientists are increasingly charged with reformulating existing...
Controlled release preparations | Controlled release technology
Controlled release preparations | Controlled release technology
Book
2007, ISBN 0849330874, 627
Book
2006, McGraw-Hill chemical engineering, ISBN 9780071417594, xii, 435
Book
1987, Pharmaceutical technology, ISBN 9780745801780, Volume 1
eBook
2003, Drugs and the pharmaceutical sciences, ISBN 0824708695, Volume 126
eBook
International Journal of Pharmaceutics, ISSN 0378-5173, 2011, Volume 415, Issue 1, pp. 34 - 52
â–º We analyze the complex picture of drug release from PLGA drug delivery systems. â–º We focus on release mechanisms, discuss ways to study it and review the...
Pore closure | Degradation | PLGA | Diffusion | Pore formation | Release mechanism | IN-VITRO RELEASE | MOLECULAR-WEIGHT | LOADED PLGA NANOPARTICLES | SOLVENT EVAPORATION METHOD | BIODEGRADABLE POLYMERIC MICROSPHERES | HUMAN GROWTH-HORMONE | INITIAL BURST RELEASE | PHARMACOLOGY & PHARMACY | POLY(D,L-LACTIC-CO-GLYCOLIC ACID) MICROSPHERES | RESERVOIR TYPE MICROSPHERES | SUSTAINED-RELEASE | Lactic Acid - chemistry | Models, Chemical | Humans | Polyglycolic Acid - chemistry | Chemical Phenomena | Solubility | Delayed-Action Preparations - chemistry | Drug Carriers - chemistry | Delayed-Action Preparations - administration & dosage | Drugs | Packaging | Drug delivery systems | Vehicles | Drug delivery | Reviews | Biodegradability | polylactide-co-glycolide | Controlled release | Pharmaceuticals | Annan teknik | Livsmedelsteknik | Engineering and Technology | Other Engineering and Technologies | Food Engineering | Kemiteknik | Chemical Engineering | Teknik
Pore closure | Degradation | PLGA | Diffusion | Pore formation | Release mechanism | IN-VITRO RELEASE | MOLECULAR-WEIGHT | LOADED PLGA NANOPARTICLES | SOLVENT EVAPORATION METHOD | BIODEGRADABLE POLYMERIC MICROSPHERES | HUMAN GROWTH-HORMONE | INITIAL BURST RELEASE | PHARMACOLOGY & PHARMACY | POLY(D,L-LACTIC-CO-GLYCOLIC ACID) MICROSPHERES | RESERVOIR TYPE MICROSPHERES | SUSTAINED-RELEASE | Lactic Acid - chemistry | Models, Chemical | Humans | Polyglycolic Acid - chemistry | Chemical Phenomena | Solubility | Delayed-Action Preparations - chemistry | Drug Carriers - chemistry | Delayed-Action Preparations - administration & dosage | Drugs | Packaging | Drug delivery systems | Vehicles | Drug delivery | Reviews | Biodegradability | polylactide-co-glycolide | Controlled release | Pharmaceuticals | Annan teknik | Livsmedelsteknik | Engineering and Technology | Other Engineering and Technologies | Food Engineering | Kemiteknik | Chemical Engineering | Teknik
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 10/2015, Volume 494, Issue 2, pp. 657 - 663
The aim of this work was to explore the feasibility of combining hot melt extrusion (HME) with 3D printing (3DP) technology, with a view to producing different...
Hot melt extrusion | Controlled-release | PVA | Fused deposition modeling | paracetamol | 3D printing | MATRIX | DOSAGE FORMS | DELIVERY | DONUT-SHAPED TABLETS | KINETICS | PHARMACOLOGY & PHARMACY | MELT EXTRUSION | FABRICATION | Polyvinyl Alcohol - chemistry | Drug Delivery Systems - instrumentation | Printing, Three-Dimensional - instrumentation | Drug Stability | Humans | Acetaminophen - administration & dosage | Drug Liberation | Hot Temperature | Technology, Pharmaceutical - instrumentation | Acetaminophen | Analysis
Hot melt extrusion | Controlled-release | PVA | Fused deposition modeling | paracetamol | 3D printing | MATRIX | DOSAGE FORMS | DELIVERY | DONUT-SHAPED TABLETS | KINETICS | PHARMACOLOGY & PHARMACY | MELT EXTRUSION | FABRICATION | Polyvinyl Alcohol - chemistry | Drug Delivery Systems - instrumentation | Printing, Three-Dimensional - instrumentation | Drug Stability | Humans | Acetaminophen - administration & dosage | Drug Liberation | Hot Temperature | Technology, Pharmaceutical - instrumentation | Acetaminophen | Analysis
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 12/2015, Volume 219, pp. 119 - 128
Tissue engineering is often referred to as a three-pronged discipline, with each prong corresponding to 1) a 3D material matrix (scaffold), 2) drugs that act...
Tissue engineering | Regenerative medicine | Polymer | Drug delivery | Scaffold | Controlled release | Biomaterials | PHARMACOLOGY & PHARMACY | CHEMISTRY, MULTIDISCIPLINARY | Polymers - administration & dosage | Humans | Delayed-Action Preparations - chemistry | Delayed-Action Preparations - administration & dosage | Drug Delivery Systems | Tissue Scaffolds | Microspheres | Animals | Hydrogels - administration & dosage | Drug Liberation | Polymers - chemistry | Hydrogels - chemistry | Tissue Engineering | Drugs | Drug delivery systems | Biological products | Engineering schools | Polymers | Vehicles | Regenerative Medicine
Tissue engineering | Regenerative medicine | Polymer | Drug delivery | Scaffold | Controlled release | Biomaterials | PHARMACOLOGY & PHARMACY | CHEMISTRY, MULTIDISCIPLINARY | Polymers - administration & dosage | Humans | Delayed-Action Preparations - chemistry | Delayed-Action Preparations - administration & dosage | Drug Delivery Systems | Tissue Scaffolds | Microspheres | Animals | Hydrogels - administration & dosage | Drug Liberation | Polymers - chemistry | Hydrogels - chemistry | Tissue Engineering | Drugs | Drug delivery systems | Biological products | Engineering schools | Polymers | Vehicles | Regenerative Medicine
Journal Article
Chemical Engineering Science, ISSN 0009-2509, 03/2015, Volume 125, pp. 75 - 84
Nanocarriers providing spatiotemporal control of drug release contribute to reducing toxicity and improving therapeutic efficacy of a drug. On the other hand,...
Drug release mechanisms | Drug release kinetics | Drug delivery | Nanocarriers | Controlled release | CANCER-CELLS | DELIVERY SYSTEMS | MESOPOROUS SILICA NANOPARTICLES | LOADED PLGA NANOPARTICLES | FUNCTIONALIZED CARBON NANOTUBES | POLYMERIC MICELLES | MACROMOLECULAR THERAPEUTICS | ENGINEERING, CHEMICAL | RESPONSIVE CONTROLLED-RELEASE | HOLLOW GOLD NANOSPHERES | IN-VIVO EVALUATION | Biomedical engineering | controlled release | drug release kinetics | drug delivery | drug release mechanisms
Drug release mechanisms | Drug release kinetics | Drug delivery | Nanocarriers | Controlled release | CANCER-CELLS | DELIVERY SYSTEMS | MESOPOROUS SILICA NANOPARTICLES | LOADED PLGA NANOPARTICLES | FUNCTIONALIZED CARBON NANOTUBES | POLYMERIC MICELLES | MACROMOLECULAR THERAPEUTICS | ENGINEERING, CHEMICAL | RESPONSIVE CONTROLLED-RELEASE | HOLLOW GOLD NANOSPHERES | IN-VIVO EVALUATION | Biomedical engineering | controlled release | drug release kinetics | drug delivery | drug release mechanisms
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 12/2011, Volume 133, Issue 49, pp. 19582 - 19585
Mesoporous silica nanoparticles (MSNPs) have garnered a great deal of attention as potential carriers for therapeutic payloads. However, achieving triggered...
DELIVERY-SYSTEM | RESPONSIVE CONTROLLED-RELEASE | IN-VITRO | NANOTECHNOLOGY | CHEMISTRY, MULTIDISCIPLINARY | Cell Survival - drug effects | Antibiotics, Antineoplastic - pharmacology | Nanoparticles - chemistry | Humans | Silicon Dioxide - chemistry | Nanoparticles - ultrastructure | Delayed-Action Preparations - chemistry | Neoplasms - drug therapy | Antibiotics, Antineoplastic - administration & dosage | Delayed-Action Preparations - metabolism | Silicon Dioxide - metabolism | Polymers - chemistry | HeLa Cells | Porosity | Doxorubicin - pharmacology | Polymers - metabolism | Doxorubicin - administration & dosage | Peptide Hydrolases - metabolism | Composition | Usage | Research | Chemical properties | Drug therapy | Doxorubicin | Silica | Pharmaceutical chemistry | Cancer | Communication
DELIVERY-SYSTEM | RESPONSIVE CONTROLLED-RELEASE | IN-VITRO | NANOTECHNOLOGY | CHEMISTRY, MULTIDISCIPLINARY | Cell Survival - drug effects | Antibiotics, Antineoplastic - pharmacology | Nanoparticles - chemistry | Humans | Silicon Dioxide - chemistry | Nanoparticles - ultrastructure | Delayed-Action Preparations - chemistry | Neoplasms - drug therapy | Antibiotics, Antineoplastic - administration & dosage | Delayed-Action Preparations - metabolism | Silicon Dioxide - metabolism | Polymers - chemistry | HeLa Cells | Porosity | Doxorubicin - pharmacology | Polymers - metabolism | Doxorubicin - administration & dosage | Peptide Hydrolases - metabolism | Composition | Usage | Research | Chemical properties | Drug therapy | Doxorubicin | Silica | Pharmaceutical chemistry | Cancer | Communication
Journal Article
ACS Nano, ISSN 1936-0851, 01/2012, Volume 6, Issue 1, pp. 227 - 233
We describe a new temperature and electric field dual-stimulus responsive nanoparticle system for programmed drug delivery. Nanoparticles of a conducting...
polypyrrole | conductive nanoparticles | controlled release | drug delivery | stimulus-responsive materials | BIOCOMPATIBILITY | BLOCK-COPOLYMERS | GENE DELIVERY | PARTICLES | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | CHEMISTRY, MULTIDISCIPLINARY | IN-VIVO | SYSTEMS | Delayed-Action Preparations - radiation effects | Electromagnetic Fields | Pharmaceutical Preparations - radiation effects | Polymers - radiation effects | Pharmaceutical Preparations - chemistry | Delayed-Action Preparations - chemistry | Materials Testing | Polymers - chemistry | Diffusion | Nanocapsules - radiation effects | Nanocapsules - chemistry | Nanoparticles | Conducting polymers | Surgical implants | Drug delivery systems | Direct current | Polypyrroles | Nanostructure | Electrically conductive | Electric fields | stimulus responsive materials
polypyrrole | conductive nanoparticles | controlled release | drug delivery | stimulus-responsive materials | BIOCOMPATIBILITY | BLOCK-COPOLYMERS | GENE DELIVERY | PARTICLES | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | CHEMISTRY, MULTIDISCIPLINARY | IN-VIVO | SYSTEMS | Delayed-Action Preparations - radiation effects | Electromagnetic Fields | Pharmaceutical Preparations - radiation effects | Polymers - radiation effects | Pharmaceutical Preparations - chemistry | Delayed-Action Preparations - chemistry | Materials Testing | Polymers - chemistry | Diffusion | Nanocapsules - radiation effects | Nanocapsules - chemistry | Nanoparticles | Conducting polymers | Surgical implants | Drug delivery systems | Direct current | Polypyrroles | Nanostructure | Electrically conductive | Electric fields | stimulus responsive materials
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 08/2013, Volume 169, Issue 3, pp. 165 - 170
Local and temporal control of drug release has for long been a main focus in the development of novel drug carriers. Polymersomes, which can load both...
Controlled drug delivery | Magnetic field | Hyperthermia | Polymersomes | Cancer therapy | Theranostic | SURVIVAL | CELLS | DESIGN | VESICLES | IRON | TOXICITY | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | NANOPARTICLES | PHARMACOLOGY & PHARMACY | Cell Survival - drug effects | Antibiotics, Antineoplastic - pharmacology | Humans | Delayed-Action Preparations - chemistry | Doxorubicin - pharmacokinetics | Neoplasms - drug therapy | Antibiotics, Antineoplastic - administration & dosage | Magnetite Nanoparticles - chemistry | Neoplasms - therapy | Hyperthermia, Induced | HeLa Cells | Magnetic Fields | Antibiotics, Antineoplastic - pharmacokinetics | Doxorubicin - pharmacology | Doxorubicin - administration & dosage | Drugs | Anthracyclines | Drug delivery systems | Drug therapy | Magnetic fields | Cancer | Vehicles | Index Medicus | Polymers | Chemical Sciences
Controlled drug delivery | Magnetic field | Hyperthermia | Polymersomes | Cancer therapy | Theranostic | SURVIVAL | CELLS | DESIGN | VESICLES | IRON | TOXICITY | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | NANOPARTICLES | PHARMACOLOGY & PHARMACY | Cell Survival - drug effects | Antibiotics, Antineoplastic - pharmacology | Humans | Delayed-Action Preparations - chemistry | Doxorubicin - pharmacokinetics | Neoplasms - drug therapy | Antibiotics, Antineoplastic - administration & dosage | Magnetite Nanoparticles - chemistry | Neoplasms - therapy | Hyperthermia, Induced | HeLa Cells | Magnetic Fields | Antibiotics, Antineoplastic - pharmacokinetics | Doxorubicin - pharmacology | Doxorubicin - administration & dosage | Drugs | Anthracyclines | Drug delivery systems | Drug therapy | Magnetic fields | Cancer | Vehicles | Index Medicus | Polymers | Chemical Sciences
Journal Article
1987, ISBN 0745801781, Volume 1, v.
Extends the concepts of Volume 1 to include drug properties, design and optimization, coating and the effect of food and pharmacokinetics. This volume also...
Drugs | Controlled release
Drugs | Controlled release
Book
Journal of Controlled Release, ISSN 0168-3659, 2011, Volume 153, Issue 3, pp. 206 - 216
Casein, the major milk protein, forms an integral part of the daily diet in many parts of the world. Casein possesses a number of interesting properties that...
Nanoparticles | Casein-drug compacts | Casein | Hydrogels | Floating beads | Microparticles | ALBUMIN HSA NANOPARTICLES | GELATIN NANOPARTICLES | SERUM-ALBUMIN | MICROBIAL TRANSGLUTAMINASE | SODIUM CASEINATE | CHEMISTRY, MULTIDISCIPLINARY | ENZYMATIC CROSS-LINKING | IN-VITRO | STREPTOVERTICILLIUM-MOBARAENSE | MICELLE STRUCTURE | BOVINE BETA-CASEIN | PHARMACOLOGY & PHARMACY | Tensile Strength | Cross-Linking Reagents - chemistry | Drug Stability | Humans | Solubility | Biological Availability | Delayed-Action Preparations - chemistry | Chemistry, Pharmaceutical | Drug Carriers - chemistry | Delayed-Action Preparations - administration & dosage | Microspheres | Animals | Caseins - chemistry | Delayed-Action Preparations - pharmacokinetics | Drug Delivery Systems - methods | Drugs | Enzymes | Drug delivery systems | Crosslinked polymers | Functional foods | Polyelectrolytes | Dosage and administration | Vehicles | Coacervation | Films | Tablets | microparticles | Drug delivery | hydrogels | Bioavailability | Protein-glutamine gamma -glutamyltransferase | Dissolution | Immunosuppressive agents | Tensile strength | Genipin | Glutaraldehyde | nutraceuticals | Controlled release | Milk
Nanoparticles | Casein-drug compacts | Casein | Hydrogels | Floating beads | Microparticles | ALBUMIN HSA NANOPARTICLES | GELATIN NANOPARTICLES | SERUM-ALBUMIN | MICROBIAL TRANSGLUTAMINASE | SODIUM CASEINATE | CHEMISTRY, MULTIDISCIPLINARY | ENZYMATIC CROSS-LINKING | IN-VITRO | STREPTOVERTICILLIUM-MOBARAENSE | MICELLE STRUCTURE | BOVINE BETA-CASEIN | PHARMACOLOGY & PHARMACY | Tensile Strength | Cross-Linking Reagents - chemistry | Drug Stability | Humans | Solubility | Biological Availability | Delayed-Action Preparations - chemistry | Chemistry, Pharmaceutical | Drug Carriers - chemistry | Delayed-Action Preparations - administration & dosage | Microspheres | Animals | Caseins - chemistry | Delayed-Action Preparations - pharmacokinetics | Drug Delivery Systems - methods | Drugs | Enzymes | Drug delivery systems | Crosslinked polymers | Functional foods | Polyelectrolytes | Dosage and administration | Vehicles | Coacervation | Films | Tablets | microparticles | Drug delivery | hydrogels | Bioavailability | Protein-glutamine gamma -glutamyltransferase | Dissolution | Immunosuppressive agents | Tensile strength | Genipin | Glutaraldehyde | nutraceuticals | Controlled release | Milk
Journal Article