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Cancer Medicine, ISSN 2045-7634, 09/2018, Volume 7, Issue 9, pp. 4447 - 4455
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2012, Volume 287, Issue 52, pp. 43543 - 43556
Endorepellin, the angiostatic C-terminal domain of the heparan sulfate proteoglycan perlecan, inhibits angiogenesis by simultaneously binding to the alpha 2... 
CANCER GROWTH | COLON CARCINOMA-CELLS | DOMAIN-III | ANGIOSTATIC ACTIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PERLECAN PROTEIN CORE | VEGF RECEPTOR-2 | HEPARAN-SULFATE PROTEOGLYCAN | BASEMENT-MEMBRANE PROTEOGLYCANS | TUMOR-GROWTH | ALPHA-2-BETA-1 INTEGRIN | Protein Kinase C - genetics | MAP Kinase Signaling System - physiology | Human Umbilical Vein Endothelial Cells - metabolism | TOR Serine-Threonine Kinases - metabolism | Active Transport, Cell Nucleus - physiology | Humans | Phosphatidylinositol 3-Kinases - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Proto-Oncogene Proteins c-akt - genetics | Vascular Endothelial Growth Factor Receptor-2 - genetics | Cell Nucleus - metabolism | MAP Kinase Kinase 4 - metabolism | TOR Serine-Threonine Kinases - genetics | Heparan Sulfate Proteoglycans - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Protein Kinase C - metabolism | Swine | Human Umbilical Vein Endothelial Cells - cytology | Proto-Oncogene Proteins c-akt - metabolism | Peptide Fragments - genetics | Protein-Serine-Threonine Kinases - metabolism | Peptide Fragments - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | NFATC Transcription Factors - metabolism | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Phosphatidylinositol 3-Kinases - genetics | Neovascularization, Physiologic - physiology | Transcription, Genetic - physiology | Animals | Cell Nucleus - genetics | Heparan Sulfate Proteoglycans - metabolism | MAP Kinase Kinase 4 - genetics | NFATC Transcription Factors - genetics | Proteoglycan | Angiogenesis | Vascular Endothelial Growth Factor (VEGF) | AP1 | VEGF Receptor 2 | Vascular Biology | Calcineurin | Perlecan | Glycobiology and Extracellular Matrices | Endothelial Cell | NFAT1
Journal Article
Archives of Pathology and Laboratory Medicine, ISSN 0003-9985, 02/2014, Volume 138, Issue 2, pp. 241 - 256
Journal Article
Journal Article
Mechanisms of Development, ISSN 0925-4773, 2001, Volume 106, Issue 1, pp. 97 - 106
Vascular endothelial growth factor (VEGF) is a critical regulator of angiogenesis during development, but little is known about the factors that control its... 
Transcription factors | Transcription | Endochondral ossification | Vascular endothelial growth factor receptors | Promoter | Angiogenesis | Transfection | Bone development | Chondrocytes | Hypoxia | In situ hybridization | Vascular endothelial growth factor | Hypertrophy | Real-time polymerase chain reaction | hypoxia | CELLS | chondrocytes | FACTOR GENE-EXPRESSION | OSTEOBLAST DIFFERENTIATION | transcription | hypertrophy | angiogenesis | transfection | real-time polymerase chain reaction | RECEPTOR | vascular endothelial growth factors | DEVELOPMENTAL BIOLOGY | FACTOR-I | VASCULAR ENDOTHELIUM | CHONDROCYTE DIFFERENTIATION | vascular endothelial growth factor receptors transcription factors | CBFA1 | bone development | EMBRYONIC LETHALITY | promoter | endochondral ossification | in situ hybridization | ENDOTHELIAL GROWTH-FACTOR | Receptors, Vascular Endothelial Growth Factor | Up-Regulation | Vascular Endothelial Growth Factor A | Chondrocytes - cytology | Endothelial Growth Factors - metabolism | Vascular Endothelial Growth Factors | Receptors, Growth Factor - genetics | In Situ Hybridization | Lymphokines - genetics | Gene Expression Regulation, Developmental | Bone and Bones - metabolism | Neoplasm Proteins | Lymphokines - metabolism | Transcription, Genetic | Core Binding Factor Alpha 1 Subunit | Tibia - metabolism | Chondrocytes - metabolism | Gene Targeting | Cartilage - embryology | Transcription Factors - physiology | Cartilage - blood supply | Tibia - embryology | Transcription Factors - genetics | Cartilage - metabolism | Receptor Protein-Tyrosine Kinases - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Transcription Factors - metabolism | Animals | Receptor Protein-Tyrosine Kinases - genetics | Endothelial Growth Factors - genetics | Mice | Bone and Bones - embryology | 3T3 Cells | Neovascularization, Physiologic | Osteogenesis | Receptors, Growth Factor - metabolism
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2012, Volume 122, Issue 9, pp. 3101 - 3113
Osteoporotic bones have reduced spongy bone mass, altered bone architecture, and increased marrow fat. Bone marrow stem cells from osteoporotic patients are... 
SURVIVAL | MEDICINE, RESEARCH & EXPERIMENTAL | COLONY-STIMULATING FACTOR | OSTEOGENIC CELLS | BONE-MARROW | TISSUE | PROLIFERATION | ADIPOGENESIS | MESENCHYMAL STEM-CELLS | OSTEOPOROSIS | ENDOTHELIAL GROWTH-FACTOR | Mesenchymal Stromal Cells - enzymology | Vascular Endothelial Growth Factor A - deficiency | Femur - pathology | Bone Marrow Cells - physiology | Male | Alkaline Phosphatase | Femur - diagnostic imaging | Adipocytes - physiology | PPAR gamma - metabolism | Vascular Endothelial Growth Factor A - genetics | Core Binding Factor Alpha 1 Subunit - metabolism | Tibia - pathology | Vascular Endothelial Growth Factor Receptor-2 - genetics | Adiposity | Osteoporosis - metabolism | Cell Differentiation | Colony-Forming Units Assay | Mesenchymal Stromal Cells - physiology | PPAR gamma - genetics | Vascular Endothelial Growth Factor Receptor-1 - genetics | Gene Expression | Bone Density | Osteoblasts - physiology | Cells, Cultured | Gene Expression Regulation | Tibia - diagnostic imaging | Mesenchymal Stromal Cells - metabolism | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Lamin Type A - metabolism | Mice, Knockout | Radiography | Animals | Osteoporosis - pathology | Bone Marrow - pathology | Mice | Osteoblasts - metabolism | Vascular Endothelial Growth Factor A - physiology | Bone Marrow Cells - metabolism | Osteogenesis | Fat cells | Growth | Genetic aspects | Cell differentiation | Properties | Vascular endothelial growth factor | Osteoblasts
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 05/2013, Volume 228, Issue 5, pp. 1076 - 1086
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 07/2011, Volume 112, Issue 7, pp. 1749 - 1760
The epidermal growth factor receptor (EGFR) and its ligands regulate key processes of cell biology, such as proliferation, survival, differentiation,... 
EGFR | Osterix | Osteoblast differentiation | Runx2 | HDAC | CELLS | OSTERIX | OSTEOBLAST DIFFERENTIATION | ACTIVATED PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BONE-DEVELOPMENT | CELL BIOLOGY | BREAST-CANCER | HISTONE DEACETYLASES | MOUSE OSTEOCALCIN GENE | EPIDERMAL-GROWTH-FACTOR | RECEPTOR ACTIVATOR | PROMOTER | KAPPA-B LIGAND | Receptor, Epidermal Growth Factor - agonists | Humans | Alkaline Phosphatase - metabolism | Osteocalcin - genetics | Amphiregulin | Glycoproteins - pharmacology | Core Binding Factor Alpha 1 Subunit - metabolism | Receptor, Epidermal Growth Factor - metabolism | EGF Family of Proteins | Transcription, Genetic | Osteoblasts - cytology | Transforming Growth Factor alpha - pharmacology | Alkaline Phosphatase - genetics | Histone Deacetylases - genetics | Histone Deacetylase 6 | Osteocalcin - metabolism | Osteoblasts - drug effects | Osteogenesis - drug effects | Histone Deacetylases - metabolism | Genetic Markers | Neuregulin-1 - pharmacology | Transcription Factors - genetics | Transcription Factors - metabolism | Heparin-binding EGF-like Growth Factor | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Sp7 Transcription Factor | Integrin-Binding Sialoprotein - genetics | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mice | Epidermal Growth Factor - pharmacology | Quinazolines - pharmacology | Integrin-Binding Sialoprotein - metabolism | 3T3 Cells | Core Binding Factor Alpha 1 Subunit - genetics | Cell proliferation | Osteoprogenitor cells | Cbfa-1 protein | Histone deacetylase | Chromatin | Transcription factors | Cell survival | Immunoprecipitation | Epidermal growth factor receptors | Bone turnover | Osteoblasts | Promoters | Polymerase chain reaction | Signal transduction | Osteoblastogenesis | Mineralization | Tumorigenesis | Bone | Cell migration | osteoblast differentiation | osterix
Journal Article