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British Journal of Ophthalmology, ISSN 0007-1161, 04/2018, Volume 102, Issue 4, pp. 556 - 561
AimsTo demonstrate and characterise distinct subepithelial compact nerve endings (CNE) at the human corneoscleral limbus.MethodsTen fresh human donor... 
experimental-laboratory | anatomy | cornea | conjunctiva | GANGLION | experimental- laboratory | ENDINGS | CORNEAL NERVES | SENSITIVITY | INNERVATION | MECHANORECEPTORS | DISEASE | OPHTHALMOLOGY | SENSORY NERVES | HEALTH | Microscopy | Limbus Corneae - innervation | Humans | Middle Aged | Aged, 80 and over | Nerve Endings | Female | Male | Aged | Sclera - innervation | Cornea | Skin | Ophthalmology | Mammals | Age
Journal Article
PLoS ONE, ISSN 1932-6203, 2018, Volume 13, Issue 11, p. e0207710
Purpose To present a novel non-parametric algorithm for detecting the position of the human eye limbus in three dimensions and a new dynamic method for... 
DISTANCE | CHAMBER INTRAOCULAR-LENS | IMPLANTATION | MULTIDISCIPLINARY SCIENCES | CORNEAL DIAMETER MEASUREMENTS | TOPOGRAPHY | ANGLE | WHITE-TO-WHITE | Eye | Research | Cataracts | Cornea | Engineering schools | Shape | Eye movements | Males | Luminous intensity | Digital imaging | Algorithms | Contours | Light intensity | Females | Methods
Journal Article
Journal Article
Journal Article
Journal Article
British Journal of Ophthalmology, ISSN 0007-1161, 04/2012, Volume 96, Issue 4, pp. 530 - 536
AimTo describe in vivo confocal microscopy (IVCM) features of the limbus in normal eyes as related to the palisades of Vogt's.Methods46 eyes of 29 consecutive... 
OPHTHALMOLOGY | STEM-CELL NICHE | EPITHELIAL CRYPT | PALISADES | VOGT | Reproducibility of Results | Epithelium, Corneal - cytology | Cell Count | Humans | Middle Aged | Cell Size | Male | Reference Values | Microscopy, Confocal - methods | Pigmentation | Young Adult | Adult | Female | Limbus Corneae - cytology | Physiological aspects | Confocal microscopy | Reports | Cornea | Usage | Analysis | Studies | Morphology | Stem cells | Software | Females | Age | Asians
Journal Article
Investigative ophthalmology & visual science, ISSN 0146-0404, 03/2019, Volume 60, Issue 4, pp. 1050 - 1062
PURPOSE. We recently reported that the glycosaminoglycan hyaluronan (HA), which promotes inflammatory angiogenesis in other vascular beds, is an abundant... 
Hyaluronan | Extracellular matrix | Inflammation | Limbus | Glycosaminoglycans | Lymphatic vessels | glycosaminoglycans | CELLS | ANGIOGENESIS | hyaluronan | RECEPTOR | INDUCTION | ORGANIZATION | INHIBITION | inflammation | limbus | VASCULATURE | lymphatic vessels | OPHTHALMOLOGY | extracellular matrix | LYVE-1 | ENDOTHELIAL GROWTH-FACTOR | Cornea
Journal Article
Stem Cells International, ISSN 1687-966X, 2017, Volume 2017, pp. 7678637 - 12
Homeostasis and regeneration of corneal epithelia are sustained by limbal epithelial stem cells (LESCs); thus, an LESC deficiency is a major cause of blindness... 
PROGENITOR CELLS | HOLOCLONES | TELOMERASE | REGENERATION | RECONSTRUCTION | SURFACE | KERATINOCYTES | EX-VIVO | EXPRESSION | TRANSPLANTATION | CELL & TISSUE ENGINEERING | Cell culture | Cornea | Cultivation | Epithelial cells | Oct-4 protein | Medical treatment | c-Myc protein | Homeostasis | Cultures | Transplantation | Genomes | Myc protein | Tissues | Medicine | Regeneration | KLF4 protein | Blindness | Stem cells | Telomerase | University colleges
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, p. e61833
Corneal epithelial stem cells or limbal stem cells (LSCs) are responsible for the maintenance of the corneal epithelium in humans. The exact location of LSCs... 
EPITHELIAL STEM-CELLS | GROWTH-FACTOR-BETA | HUMAN CORNEA | SIDE POPULATION CELLS | MULTIDISCIPLINARY SCIENCES | SELF-RENEWAL | STEM/PROGENITOR CELLS | PROLIFERATION | OCULAR SURFACE EPITHELIA | EXPRESSION | BASAL-CELLS | Sialoglycoproteins - genetics | Tenascin - genetics | Homeodomain Proteins - metabolism | Humans | Middle Aged | Sialoglycoproteins - metabolism | Transcriptome | Gene Expression Profiling | Gene Regulatory Networks | Tenascin - metabolism | Conjunctiva - metabolism | Young Adult | Bone Morphogenetic Proteins - metabolism | Limbus Corneae - metabolism | Adult | Extracellular Matrix Proteins - metabolism | Wnt Signaling Pathway | Fibromodulin | Stem Cell Niche | Extracellular Matrix Proteins - genetics | Molecular Sequence Annotation | Gene Expression Regulation | Frizzled Receptors - metabolism | Proteoglycans - metabolism | Transcription Factors - genetics | Organ Specificity | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Cornea - metabolism | Adult Stem Cells - metabolism | Frizzled Receptors - genetics | Aged | Limbus Corneae - cytology | Transforming Growth Factor beta - metabolism | Proteoglycans - genetics | Bone morphogenetic proteins | Transforming growth factors | Analysis | Genes | Stem cells | Tenascin | Cornea | Wnt protein | Tenascin C | Frizzled protein | Regulatory sequences | Conjunctiva | Gene expression | Epithelium | Biological activity | Homeobox | Proteins | Signaling | Network analysis | Cell adhesion | Localization | Growth factors
Journal Article