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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2011, Volume 108, Issue 51, pp. 20701 - 20706
Blockade of the CD40/CD154 pathway potently attenuates T-cell responses in models of autoimmunity, inflammation, and transplantation. Indeed, CD40 pathway... 
T lymphocytes | Antigens | Cytokines | Transgenic animals | Homologous transplantation | Transplantation | Mice | Blood transfusion | Tissue grafting | Graft rejection | Costimulation blockade | NONHUMAN-PRIMATES | RENAL-ALLOGRAFT REJECTION | DENDRITIC CELLS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | ENDOTHELIAL-CELLS | CD40 LIGAND | DONOR-SPECIFIC TRANSFUSION | costimulation blockade | PRECURSOR FREQUENCY | ANTI-CD154 MONOCLONAL-ANTIBODY | CUTTING EDGE | Forkhead Transcription Factors - biosynthesis | Graft Survival - immunology | Cytokines - metabolism | Mice, Inbred C57BL | Interleukin-2 Receptor alpha Subunit - biosynthesis | CD40 Ligand - biosynthesis | Mice, Transgenic | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | CD40 Antigens - biosynthesis | Animals | Immune Tolerance - immunology | T-Lymphocytes, Regulatory - cytology | Skin Transplantation | CD8-Positive T-Lymphocytes - immunology | Signal transduction | T cell receptors | Rodents | Index Medicus | Autoimmunity | Ovalbumin | Animal models | CD40 antigen | Transfusion | Anergy | CD8 antigen | Immunoregulation | Transgenic mice | Inflammation | Lymphocytes T | CD4 antigen | T-cell receptor | Molecular modelling | gamma -Interferon | CD25 antigen | Foxp3 protein | Skin | CD154 antigen | Kinetics | Differentiation | Biological Sciences
Journal Article
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 12/2015, Volume 15, Issue 12, pp. 3081 - 3094
Journal Article
Journal Article
Xenotransplantation, ISSN 0908-665X, 05/2015, Volume 22, Issue 3, pp. 211 - 220
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 02/2014, Volume 211, Issue 2, pp. 297 - 311
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2016, Volume 113, Issue 27, pp. E3901 - E3910
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2017, Volume 23, Issue 20, pp. 6165 - 6177
Purpose: Antibodies specific for inhibitory checkpoints PD-1 and CTLA-4 have shown impressive results against solid tumors. This has fueled interest in novel... 
ONCOLOGY | THERAPEUTIC-EFFICACY | IMMUNE-RESPONSES | POOR-PROGNOSIS | CD4(+) T-CELLS | COSTIMULATORY MOLECULE | ESTABLISHED MELANOMA | OVARIAN-CANCER | HUMAN BREAST-CANCER | LYMPHOPENIC HOSTS | ANTITUMOR EFFICACY | T-Lymphocyte Subsets - immunology | Immunotherapy - methods | Humans | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Receptors, OX40 - metabolism | Time Factors | T-Lymphocyte Subsets - drug effects | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Molecular Targeted Therapy - methods | Cytokines - blood | Disease Models, Animal | Cytokines - metabolism | Receptors, Antigen, T-Cell - metabolism | Programmed Cell Death 1 Receptor - metabolism | Immunophenotyping | Mice, Transgenic | Survival Rate | Treatment Outcome | Lymphocytes, Tumor-Infiltrating - drug effects | Antineoplastic Agents, Immunological - pharmacology | Xenograft Model Antitumor Assays | Animals | Antineoplastic Agents, Immunological - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | T-Lymphocyte Subsets - metabolism | Lymphocyte Count | Mice | Lymphocytes, Tumor-Infiltrating - immunology | Receptors, OX40 - antagonists & inhibitors | Cell proliferation | Animal models | PD-1 protein | CD8 antigen | Clinical trials | Antibodies | Lymphocytes T | Contraction | Anticancer properties | Receptors | CTLA-4 protein | Cell activation | Cell growth | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Immunotherapy | Medical research | Cytokines | T cell receptors | CD4 antigen | Immune checkpoint | Experimental design | Tumor necrosis factor | Exhaustion | Antitumor activity | Solid tumors | Tumors | Cancer | Index Medicus | Combination immunotherapy | T cells | Costimulation | Checkpoint blockade
Journal Article
Clinical & Experimental Allergy, ISSN 0954-7894, 01/2014, Volume 44, Issue 1, pp. 29 - 37
Journal Article