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Journal of Structural Biology, ISSN 1047-8477, 05/2018, Volume 202, Issue 2, pp. 170 - 174
We have developed a self-blotting TEM grid for use with a novel instrument for vitrifying samples for cryo-electron microscopy (cryoEM). Nanowires are grown on... 
TEM grids | Spotiton | Nanowire grids | cryoEM vitrification | nanowire grids
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 09/2019, Volume 431, Issue 19, pp. 3913 - 3919
Lewy bodies, hallmarks of Parkinson's disease, contain C-terminally truncated (ΔC) α-synuclein (α-syn). Here, we report fibril structures of three N-terminally... 
cryoEM | amyloid | thioflavin T | Raman spectroscopy | TEM | Index Medicus
Journal Article
Cell, ISSN 0092-8674, 2/2018, Volume 172, Issue 5, pp. 966 - 978.e12
Ebola virus nucleoprotein (eNP) assembles into higher-ordered structures that form the viral nucleocapsid (NC) and serve as the scaffold for viral RNA... 
Ebola virus | nucleocapsid | nucleoprotein | cryoEM | viral RNA synthesis
Journal Article
JOURNAL OF STRUCTURAL BIOLOGY, ISSN 1047-8477, 05/2018, Volume 202, Issue 2, pp. 170 - 174
We have developed a self-blotting TEM grid for use with a novel instrument for vitrifying samples for cryo-electron microscopy (cryoEM). Nanowires are grown on... 
BIOPHYSICS | Spotiton | Nanowire grids | BIOCHEMISTRY & MOLECULAR BIOLOGY | TEM grids | cryoEM vitrification | CELL BIOLOGY
Journal Article
IEEE/ACM Transactions on Computational Biology and Bioinformatics, ISSN 1545-5963, 7/2019, pp. 1 - 1
In cryo-electron microscopy, RELION is a powerful tool for high-resolution reconstruction. Due to the complicated imaging procedure and the heterogeneity of... 
CUDA | RELION | Top-k Selection | cryoEM | Statistical Method | Index Medicus
Journal Article
Structure, ISSN 0969-2126, 01/2019, Volume 27, Issue 1, pp. 134 - 139.e3
Recent advances in single-particle cryo-electron microscopy (cryoEM) have resulted in determination of an increasing number of protein structures with resolved... 
glycoproteins | refinement | cryoEM | glycans | REFINEMENT | PHENIX | BIOPHYSICS | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 2005, Volume 349, Issue 5, pp. 948 - 960
Two-dimensional crystals of dimeric photosynthetic reaction centre–LH1–PufX complexes have been analysed by cryoelectron microscopy. The 8.5 Å resolution... 
light harvesting core complex | PufX | 2D crystal | cryoEM | photosynthesis | Light harvesting core complex | Photosynthesis | CryoEM
Journal Article
International Journal of Biomedicine, ISSN 2158-0510, 06/2019, Volume 9, Issue Suppl_1, pp. S17 - S17
Background: Membrane complexes are of great importance for cell functioning. Among the best studied complexes are rotor ATPases which create ATP from ADP, or... 
molecular dynamics simulations | rotor ATPase | CryoEM
Journal Article
Journal of Structural Biology, ISSN 1047-8477, 05/2018, Volume 202, Issue 2, pp. 161 - 169
We present an update describing new features and applications of Spotiton, a novel instrument for vitrifying samples for cryoEM. We have used Spotiton to... 
piezo dispensing | nanowire grids | cryoEM vitrification | SYSTEM | PARTICLE CRYO-EM | BIOPHYSICS | CRYOELECTRON MICROSCOPY | BIOCHEMISTRY & MOLECULAR BIOLOGY | SAMPLES | ELECTRON-MICROGRAPHS | TEM | CELL BIOLOGY
Journal Article
by Zhao, HY and Li, KP and Lynn, AY and Aron, KE and Yu, GM and Jiang, W and Tang, L
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 04/2017, Volume 114, Issue 14, pp. 3601 - 3606
The enormous prevalence of tailed DNA bacteriophages on this planet is enabled by highly efficient self-assembly of hundreds of protein subunits into highly... 
atomic structure | PROVIDE | cryoEM | MECHANISM | MULTIDISCIPLINARY SCIENCES | virus assembly | DNA packaging | REVEAL | bacteriophage | CAPSID MATURATION | SILK | MOTOR | FORCES | PROTEINS
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 2009, Volume 392, Issue 1, pp. 181 - 190
Journal Article
Molecular Neurodegeneration, ISSN 1750-1326, 12/2019, Volume 14, Issue 1, pp. 1 - 14
Abstract Alpha-synuclein (αS) is the major constituent of Lewy bodies and a pathogenic hallmark of all synucleinopathathies, including Parkinson’s disease... 
Oligomers | Amyloid | Alpha-synuclein | Parkinson’s disease | Protein-protein interactions | CryoEM
Journal Article
PLoS Biology, ISSN 1544-9173, 01/2012, Volume 10, Issue 1, pp. e1001244 - e1001244
A set of software tools for building and distributing models of macromolecular assemblies uses an integrative structure modeling approach, which casts the... 
DOCKING | PACKAGE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NUCLEAR-PORE COMPLEX | MOLECULAR ARCHITECTURE | RESOLUTION | BIOLOGY | DYNAMICS | SIMULATION | CRYOEM | EFFICIENT | RIBOSOME | Models, Molecular | Computational Biology - methods | Software | Macromolecular Substances - chemistry | RNA Polymerase II - chemistry | Humans | Studies | Accuracy | RNA polymerase | Experiments | Index Medicus
Journal Article
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, ISSN 2053-2733, 2016, Volume 72, Issue a1, pp. S105 - S105
Conference Proceeding
Journal of Structural Biology, ISSN 1047-8477, 2006, Volume 155, Issue 3, pp. 470 - 481
One of the goals in developing our automated electron microscopy data acquisition system, Leginon, was to improve both the ease of use and the throughput of... 
Metadata | Database | Automation | Single particle reconstruction | TEM | CryoEM
Journal Article
Nature, ISSN 0028-0836, 02/2012, Volume 482, Issue 7384, pp. 186 - 191
Journal Article