X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (8895) 8895
Dissertation (3183) 3183
Publication (1416) 1416
Book Chapter (599) 599
Book / eBook (419) 419
Book Review (285) 285
Newsletter (262) 262
Newspaper Article (216) 216
Conference Proceeding (61) 61
Reference (51) 51
Patent (4) 4
Paper (3) 3
Data Set (1) 1
Magazine Article (1) 1
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (4185) 4185
humans (3948) 3948
animals (3894) 3894
cell biology (2574) 2574
proteins (2456) 2456
biochemistry & molecular biology (2195) 2195
molecular biology (1931) 1931
signal transduction (1914) 1914
cellular biology (1717) 1717
mice (1239) 1239
research (1177) 1177
oncology (1153) 1153
biochemistry (1108) 1108
biology (1074) 1074
cancer (1049) 1049
g proteins (1039) 1039
article (1001) 1001
activation (945) 945
mutation (937) 937
protein binding (912) 912
physiological aspects (861) 861
phosphorylation (816) 816
analysis (784) 784
biophysics (784) 784
molecular sequence data (777) 777
amino acid sequence (744) 744
genetic aspects (703) 703
neurosciences (692) 692
kinases (683) 683
genetics (641) 641
gene expression (618) 618
cells (612) 612
ras (603) 603
protein (599) 599
multidisciplinary sciences (597) 597
microbiology (596) 596
research article (585) 585
expression (574) 574
models, biological (570) 570
cytoskeleton (553) 553
signal transduction - physiology (551) 551
actin (537) 537
female (537) 537
male (532) 532
medicine (527) 527
rho gtp-binding proteins - metabolism (527) 527
immunology (516) 516
rats (512) 512
cell line (502) 502
physiology (494) 494
guanosine triphosphate - metabolism (488) 488
life sciences (466) 466
genetics & heredity (460) 460
ras proteins - metabolism (443) 443
guanine nucleotide exchange factors - metabolism (432) 432
binding (427) 427
apoptosis (426) 426
pharmacology (426) 426
rho-gtpases (424) 424
cells, cultured (422) 422
cell line, tumor (421) 421
health aspects (407) 407
models, molecular (407) 407
rab gtp-binding proteins - metabolism (398) 398
plasma-membrane (395) 395
developmental biology (391) 391
protein structure, tertiary (387) 387
gtpases (386) 386
guanosinetriphosphatase (386) 386
binding sites (381) 381
science (374) 374
gtp-binding proteins - metabolism (371) 371
actin cytoskeleton (369) 369
cell membrane - metabolism (365) 365
gtpase (365) 365
rho gtpases (365) 365
growth (364) 364
rhoa gtp-binding protein - metabolism (364) 364
protein transport (357) 357
gtpase-activating protein (356) 356
actins - metabolism (352) 352
metastasis (352) 352
identification (348) 348
rac1 gtp-binding protein - metabolism (347) 347
genes (342) 342
cdc42 (335) 335
gtp phosphohydrolases - metabolism (333) 333
cell adhesion & migration (330) 330
crystal-structure (330) 330
muscle proteins (329) 329
gtpase-activating proteins - metabolism (326) 326
in-vivo (326) 326
review (326) 326
tumors (326) 326
enzyme activation (324) 324
cell (320) 320
family (320) 320
localization (318) 318
cellular signal transduction (317) 317
protein conformation (317) 317
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (294) 294
Collection Dvlpm't (Acquisitions) - Closed Orders (56) 56
UofT at Mississauga - Stacks (34) 34
Collection Dvlpm't (Acquisitions) - Vendor file (25) 25
UTL at Downsview - May be requested (25) 25
Online Resources - Online (23) 23
UofT at Scarborough - Stacks (19) 19
Media Commons - Microtexts (18) 18
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (14) 14
Earth Sciences (Noranda) - Stacks (10) 10
Gerstein Science - Reference (8) 8
St. Michael's Hospital - Stacks (8) 8
Trinity College (John W Graham) - Stacks (6) 6
Chemistry (A D Allen) - Stacks (5) 5
Dentistry (Harry R Abbott) - May be requested in 6-10 wks (5) 5
Gerstein Science - Circulation Desk (5) 5
Gerstein Science - Theses (4) 4
Scarborough Hospital - Birchmount (4) 4
Scarborough Hospital - General (4) 4
Dentistry (Harry R Abbott) - Stacks (3) 3
Humber River Regional Hospital - Church Stacks (3) 3
Providence Healthcare - Stacks (3) 3
UofT at Mississauga - Reference (3) 3
UofT at Scarborough - Withdrawn (3) 3
Baycrest Hospital - Stacks (2) 2
Dentistry (Harry R Abbott) - Withdrawn (2) 2
Earth Sciences (Noranda) - Missing (2) 2
Gerstein Science - Missing (2) 2
Humber River Regional Hospital - Finch Stacks (2) 2
Markham Stouffville Hospital - Stacks (2) 2
Physics - Stacks (2) 2
Providence Healthcare - Reference (2) 2
St. Michael's Hospital - Circulation Desk (2) 2
Toronto East General Hospital - Stacks (2) 2
Victoria University E.J. Pratt - Reference (2) 2
Chemistry (A D Allen) - Reference (1) 1
Collection Dvlpm't (Acquisitions) - May be requested (1) 1
Collection Dvlpm't (Acquisitions) - Reference (1) 1
Collection Dvlpm't (Acquisitions) - Stacks (1) 1
Credit Valley Hospital - Reserve desk (1) 1
Credit Valley Hospital - Stacks (1) 1
Dentistry (Harry R Abbott) - Closed Orders (1) 1
Earth Sciences (Noranda) - Circulation Desk (1) 1
Engineering & Comp. Sci. - Reference (1) 1
Engineering & Comp. Sci. - Stacks (1) 1
Gerstein Science - Course Reserves (1) 1
Gerstein Science - Searching (1) 1
Holland Bloorview Kids Rehabilitation - Reference (1) 1
Lakeridge Health Sciences - Oshawa (1) 1
Missing (1) 1
Mt Sinai Hospital - Pathology (1) 1
Providence Healthcare - Reserve desk (1) 1
Providence Healthcare - Withdrawn (1) 1
Scarborough Hospital - Closed Orders (1) 1
St Josephs Health Centre - General (1) 1
St Josephs Health Centre - Stacks (1) 1
St. Michael's College (John M. Kelly) - 2nd Floor (1) 1
Trillium Health Centre - Reserve desk (1) 1
Trinity College (John W Graham) - Oversize (1) 1
Trinity College (John W Graham) - Reference (1) 1
UofT at Mississauga - May be requested (1) 1
UofT at Mississauga - Missing (1) 1
UofT at Scarborough - Sunnybrook Stacks (1) 1
Victoria University E.J. Pratt - Circulation Desk (1) 1
Victoria University E.J. Pratt - Oversize (1) 1
Women's College Hospital - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (13359) 13359
Spanish (58) 58
Japanese (15) 15
French (7) 7
Czech (6) 6
Portuguese (6) 6
German (4) 4
Turkish (4) 4
Arabic (3) 3
Chinese (1) 1
Hungarian (1) 1
Italian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


FEBS Letters, ISSN 0014-5793, 12/2015, Volume 589, Issue 24, pp. 3760 - 3772
Glial cell line-derived neurotrophic factor (GDNF) and its canonical receptor Ret can signal together or independently to fulfill many important functions in... 
Rearranged during transfection | Parkinson disease | Drug addiction | Mouse model | Dopaminergic system | Glia cell line-derived neurotrophic factor | MAOA/MAOB | orphan nuclear receptor and transcription factor | cytoplasmic SH2 domain containing protein tyrosine phosphatase | Ras | RRF | COMT | PTEN-induced putative kinase 1 | SH3 and multiple ankyrin repeat domains 3, proline-rich synapse-associated protein 2 (ProSAP2) | PI3K | sorting protein-related receptor with A-type repeats, a member of the mammal Vps10p domain receptor | subunits of the Ca2+-sensitive, voltage gated A-type K+ channel | SH2 domain containing transforming protein 1 | Nurr1 | proprotein convertases | protein kinase B, serine/threonine-specific protein kinase | calcium-calmodulin-dependent protein kinase II β isoform | FRS2 | phosphatase and tensin homolog | catecholamine | SHP-2 | growth factor receptor-bound protein 2, 7 and 10, adaptor proteins | fibroblast growth factor receptor substrate 2, adaptor protein | monoamine oxidases A and B | carbonyl cyanide m-chlorophenyl hydrazone | ERK | brain derived neurotrophic factor | deglycase, oxidative stress sensor and redox-sensitive chaperone and protease | VTA | tyrosines, which can be phosphorylated | cAMP | extracellular-signal-regulated kinases, classical MAPKs | CaMKIIβ | Kv4.3 and KChip3 | GRB2/7/10 | Ser/Thr | SNP | endoplasmatic reticulum | nerve growth factor | monoamine, neurotransmitter type including dopamine, epinephrine (adrenaline) and norepinephrine (noradrenaline) | TGF-β | Akt, PKB | phospholipase γ cleaves the phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2) into diacyl glycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) ppp3R1/ppp3CB, calcineurin subunits | PC5A, PC5B, and PC7 | EGR1 | proprotein convertase subtilisin/kexin type 6 | substantia nigra | phosphotyrosine-interaction domain | BDNF | adaptor protein of the PDZ-LIM family | γ-aminobutyric acid, inhibitory neurotransmitter in mammalian central nervous system | Tyr | FosB/ΔFosB | IRS1/2 | LIM | dopamine transporter | enhanced green fluorescent protein | GDNF | DAT | SOS | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | retro-rubal field | transforming growth factor β is a secreted protein that controls proliferation and cellular differentiation | MPTP | GTPase | hypoxia-inducible factor-1alpha | GDNF family of ligands | Ret | GPI | Shank3 | NCAM | Enigma | JNK | (rearranged during transfection) canonical GDNF receptor, a receptor tyrosine kinase | PTEN | 6-OHDA | DJ-1 | (rapidly accelerated fibrosarcoma/rat fibrosarcoma) family of serine/threonine-protein kinase | SHC | NF-κB | (acronym combining the first letters of three proteins – post synaptic density protein (PSD95), Drosophila disc large tumor suppressor (Dlg1), and zonula occludens-1 protein (zo-1) that have this common domain) protein interaction domain | phosphotyrosine-binding domains | insulin receptor substrate 1, adaptor protein, contains a PTB and PH domain | Rac1 | GFRα | nuclear factor ‘kappa-light-chain-enhancer’ of activated B-cells, transcription factor family with Rel homology domain (RHD) | catechol-O-methyltransferase | early growth response protein 1, Zif268 (zinc finger protein 225), NGFI-A (nerve growth factor-induced protein A), is a zinc finger transcription factor | serine and threonine, which can be phosphorylated | GDNF family receptor α | PKA | protein kinase A, a family of cAMP-dependent protein kinase | MAPK | NGF | SorLA | ventral tegmental area | son of sevenless, family of guanine nucleotide exchange factors that act on Ras | GABA | HIF-1a | Ras-related C3 botulinum toxin substrate 1 (Rho family), a small GTPase, like CDC42 | GAP1/2 | PTB | (Rat sarcoma) family of small membrane-associated GTPase | cycles between an active GTP-bound and an inactive GDP-bound state | glycogen synthase kinase 3β | Src | glia cell line-derived neurotrophic factor | PACE4, PCSK6 | pleckstrin homology domain | co-repressor for element-1-silencing transcription factor, a chromatin-modifying corepressor complex that acts with REST (repressor for element-1 silencing transcription factor) complex | c-Jun N-terminal kinases, members of the MAPK family of proteins | EGFP | cell division control protein 42 homolog, a plasma membrane-associated small GTPase of the Rho family | (acronym combining the first letters of three proteins – Lin11, Isl-1 and Mec-3 – that have this common domain) protein interaction domain of two contiguous zinc finger domains, separated by a two-amino acid residue hydrophobic linker | CCCP | (sarcoma protein) membrane-associated tyrosine kinase with different Src homology (SH) domains characteristic for all 9 members of the Src family kinases | DOK1/4/5/6 | (Ras homolog) family of small GTPases including Cdc42, Rac1, and RhoA | single-nucleotide polymorphism analysis | VPS10P | Rho | MEN2B | phosphatidylinositol-4,5-bisphosphate 3-kinase | 6-hydroxy-dopamine | mitogen-activated protein kinase, can phosphorylate serine, threonine, and tyrosine, e.g. p38MAPK | Cdc42 | docking proteins, have a PH and SH3 domain | GFLs | PDZ | vacuolar protein sorting 10 protein-domain receptors are type 1 transmembrane proteins | PLCγ | GTPase-activating proteins 1 and 2 | 3′,5′-cyclic adenosine monophosphate | neuronal cell adhesion molecule | TIEG | TGF-β-inducible early-response gene, a zinc finger transcription factor Vav2, adaptor protein and guanine nucleotide exchange factor for the Rho family of Ras-related GTPases | PINK1 | Raf | CoREST | multiple endocrine neoplasia 2 type B, mutation in the kinase domain of the Ret leading to constitutive active receptor | dopaminergic | glycosylphosphatidylinositol | FBJ murine osteosarcoma viral oncogene homolog B, a transcription factor with a truncated Δ form | gsk3β | ENTERIC NERVOUS-SYSTEM | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUBSTANTIA-NIGRA | CELL BIOLOGY | MICE LACKING GDNF | C-RET | BIOPHYSICS | NEUROTROPHIC FACTOR PROMOTES | MULTIPLE ENDOCRINE NEOPLASIA | SURVIVAL IN-VIVO | RECEPTOR TYROSINE KINASE | CELL-LINE | EARLY-ONSET PARKINSONISM | Glial Cell Line-Derived Neurotrophic Factor - physiology | Parkinson Disease - pathology | Animals | Proto-Oncogene Proteins c-ret - physiology | Dopamine - physiology | Mesencephalon - metabolism | Humans | Dopaminergic Neurons - physiology | Parkinson Disease - metabolism | Synaptic Transmission | Mesencephalon - pathology | Physiological aspects | Neurons | Parkinson's disease
Journal Article
eLife, ISSN 2050-084X, 10/2019, Volume 8
The RhoGTPases are characterized as membrane-associated molecular switches that cycle between active, GTP-bound and inactive, GDP-bound states. However, 90-95%... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2019, Volume 116, Issue 7, pp. 2551 - 2560
Journal Article