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The Plant Cell, ISSN 1040-4651, 7/2012, Volume 24, Issue 7, pp. 2765 - 2778
Journal Article
NeuroMolecular Medicine, ISSN 1535-1084, 9/2017, Volume 19, Issue 2, pp. 271 - 285
We have demonstrated that arginine-rich and poly-arginine peptides possess potent neuroprotective properties with arginine content and peptide positive charge... 
Neurology | Neuroprotection | Neurosciences | Stroke | Biomedicine | Protamine | Excitotoxicity | Middle cerebral artery occlusion (MCAO) | Tryptophan | Internal Medicine | Poly-arginine | NMDA RECEPTOR | MOLECULAR-WEIGHT PROTAMINE | EFFICACY | CELL-PENETRATING PEPTIDES | TOXICITY | NEUROSCIENCES | INTERNALIZATION | NEURONAL DEATH | POLYARGININE PEPTIDES | MEDIATOR PROTEIN-2 CRMP2 | Neuroprotective Agents - therapeutic use | Tryptophan - chemistry | Male | Peptides, Cyclic - pharmacology | Cerebral Cortex - cytology | Amino Acids - pharmacology | Oligopeptides - therapeutic use | Neuroprotective Agents - pharmacology | Infarction, Middle Cerebral Artery - drug therapy | Drug Evaluation, Preclinical | Neurons - drug effects | Astrocytes - drug effects | Oligopeptides - chemical synthesis | Protamines - chemistry | Cells, Cultured | Rats | Infarction, Middle Cerebral Artery - pathology | Rats, Sprague-Dawley | Arginine - chemistry | Neuroprotective Agents - chemical synthesis | Animals | Cerebral Cortex - embryology | Peptides, Cyclic - chemical synthesis | Calcium Signaling - drug effects | Peptides, Cyclic - therapeutic use | Glutamic Acid - toxicity | In Vitro Techniques | Oligopeptides - pharmacology | Amino acids | Nervous system diseases | Peptides | Glutamate | Occlusion | Glutamic acid | Animal models | In vitro testing | Leucine | Glycine | Calcium influx | Ischemia | Arginine | Cerebral blood flow | Rodents | Biocompatibility | Tyrosine | Edema | Effectiveness | Phenylalanine | Properties (attributes) | In vivo methods and tests
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 12/2014, Volume 136, Issue 51, pp. 17734 - 17737
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 02/2017, Volume 56, Issue 6, pp. 1525 - 1529
Journal Article
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 02/2019, Volume 58, Issue 6, pp. 1684 - 1688
Bioorthogonal late‐stage diversification of structurally complex peptides has enormous potential for drug discovery and molecular imaging. In recent years,... 
peptides | cobalt | C−H activation | metathesis | cyclopeptides | TRYPTOPHAN | PALLADIUM | ARYLATION | ALLYLATION | AMIDATION | ALPHA-AMINO-ACIDS | CHEMISTRY, MULTIDISCIPLINARY | CARBON-HYDROGEN | FUNCTIONALIZATION | C-H activation | BONDS | STEREOSELECTIVE-SYNTHESIS | Activation | Palladium | Catalysts | Peptides | Cobalt | Metathesis
Journal Article
Journal Article