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Journal Article
Nature, ISSN 0028-0836, 06/2017, Volume 546, Issue 7658, pp. 426 - 430
D-type cyclins (D1, D2 and D3) and their associated cyclin-dependent kinases (CDK4 and CDK6) are components of the core cell cycle machinery that drives cell... 
FLUX ANALYSIS | SITE | CATABOLISM | PYRUVATE-KINASE | GLUTAMINE | PHOSPHOFRUCTOKINASES | MULTIDISCIPLINARY SCIENCES | CDK4/6 INHIBITION | PROTEIN-PHOSPHORYLATION | CONFIDENCE | Cyclin-Dependent Kinase 6 - antagonists & inhibitors | Neoplasms - metabolism | Pentose Phosphate Pathway - drug effects | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Humans | Glycolysis - drug effects | Aminopyridines - therapeutic use | Female | Purines - therapeutic use | Phosphorylation - drug effects | Cyclin-Dependent Kinase 4 - antagonists & inhibitors | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Cyclin D3 - metabolism | Cell Survival - drug effects | Pyruvate Kinase - metabolism | Purines - pharmacology | Reactive Nitrogen Species - metabolism | Neoplasms - enzymology | Cyclin-Dependent Kinase 6 - metabolism | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - enzymology | Cyclin-Dependent Kinase 4 - metabolism | Serine - metabolism | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Animals | Aminopyridines - pharmacology | Cell Line, Tumor | Mice | Oxidative Stress - drug effects | Cell Cycle - drug effects | Neoplasms - pathology | Phosphofructokinase-1 - metabolism | Phosphates | Reactive oxygen species | Phosphorylation | Brain cancer | Clinical trials | Catalytic activity | Kinases | Cyclin-dependent kinase 6 | Machinery | Cyclin-dependent kinase 4 | Cyclin D3 | Proteins | Antioxidants | Pathways | Metabolites | Pentose | Xenografts | Cell cycle | Inhibition | NADP | Cyclin D | Catalysis | Phosphofructokinase | Glutathione | Pentose phosphate | Enzymes | Medical research | Oxygen | Cell survival | Pyruvate kinase | Cyclin-dependent kinases | Metabolism | Survival | Cyclins | Intermediates | Cell death | Glycolysis | Scientific imaging | Mass spectrometry | Tumors | Apoptosis | Cancer | 6-Phosphofructokinase | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, pp. e51407 - e51407
Journal Article
Journal Article
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2017, Volume 18, Issue 8, pp. 911 - 920
Developing pre-B cells in the bone marrow alternate between proliferation and differentiation phases. We found that protein arginine methyl transferase 1... 
PROTEIN RAG-2 | BTG2 | ACUTE LYMPHOBLASTIC-LEUKEMIA | IN-VIVO | V(D)J RECOMBINATION | RECEPTOR | ARGININE METHYLATION | RAG-2 ACCUMULATION | IMMUNOLOGY | TUMOR SUPPRESSORS | CYCLE | Genes, abl - genetics | Homeodomain Proteins - metabolism | Precursor Cells, B-Lymphoid - metabolism | Lymphopoiesis - genetics | Gene Knockdown Techniques | DNA-Binding Proteins - metabolism | Immunoglobulin Light Chains - genetics | Cell Differentiation - genetics | Immediate-Early Proteins - metabolism | Flow Cytometry | Mass Spectrometry | Tumor Suppressor Proteins - genetics | Protein-Arginine N-Methyltransferases - genetics | Gene Rearrangement, B-Lymphocyte - genetics | Real-Time Polymerase Chain Reaction | Cyclin D3 - metabolism | Cell Proliferation - genetics | Tumor Suppressor Proteins - metabolism | Cyclin-Dependent Kinase 4 - metabolism | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Protein-Arginine N-Methyltransferases - metabolism | Cell Cycle Checkpoints | Animals | Immediate-Early Proteins - genetics | Precursor Cells, B-Lymphoid - cytology | Mice | RNA, Small Interfering | Methyltransferases | Leukemia | Development and progression | Genetic aspects | B cells | Cell differentiation | Health aspects | Cell proliferation | Translocation | BCR protein | Cyclin-dependent kinases | Differentiation (biology) | Kinases | BTG2 protein | Cyclin-dependent kinase 4 | Critical components | Proteins | Cyclin-dependent kinase | RAG2 protein | Arginine | Lymphocytes B | RAG1 protein | Cell cycle | Bone marrow | Leukemogenesis | Index Medicus
Journal Article
Journal Article