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Journal of Clinical Investigation, ISSN 0021-9738, 03/2014, Volume 124, Issue 3, pp. 1083 - 1097
Genetic variation at the chromosome 9p21 risk locus promotes cardiovascular disease; however, it is unclear how or which proteins encoded at this locus... 
ENDOTHELIAL LIPASE | MEDICINE, RESEARCH & EXPERIMENTAL | SEQUENCE VARIANT | CHOLESTEROL EFFLUX | SUSCEPTIBILITY | MUSCLE-CELL APOPTOSIS | CHROMOSOME 9P21 | ABC TRANSPORTERS | CORONARY-HEART-DISEASE | EXPRESSION | MOUSE MODELS | Plaque, Atherosclerotic - genetics | Atherosclerosis - genetics | Coculture Techniques | Humans | Male | Atherosclerosis - enzymology | Plaque, Atherosclerotic - enzymology | Cyclin-Dependent Kinase Inhibitor p15 - genetics | Calreticulin - metabolism | Female | Plaque, Atherosclerotic - pathology | E2F4 Transcription Factor - metabolism | Macrophages - physiology | Atherosclerosis - pathology | Coronary Vessels - pathology | Gene Expression | Myocytes, Smooth Muscle - enzymology | Down-Regulation | Mice, Inbred C57BL | Retinoblastoma Protein - metabolism | Cells, Cultured | Mice, Knockout | E2F4 Transcription Factor - genetics | Animals | Retinoblastoma Protein - genetics | Carotid Arteries - pathology | Mice | Cyclin-Dependent Kinase Inhibitor p15 - metabolism | Quantitative Trait Loci | Necrosis - enzymology | Phagocytosis | Apoptosis | Physiological aspects | Development and progression | Enzyme inhibitors | Genetic variation | Identification and classification | Atherosclerosis | Studies | Heart attacks | Cardiovascular disease | Software | Genomes | Grants | Kinases | Laboratory animals | Gene expression | Experiments | Index Medicus | Abridged Index Medicus
Journal Article
by Weng, X and Zeng, LX and Yan, FF and He, MX and Wu, XQ and Zheng, DY
ONCOTARGETS AND THERAPY, ISSN 1178-6930, 2019, Volume 12, pp. 5025 - 5036
Purpose: The sensitivity of advanced hepatocellular carcinoma (HCC) to Sorafenib is low. The purpose of this study was to investigate the effects of... 
ADVANCED HEPATOCELLULAR-CARCINOMA | SURVIVAL | APOPTOSIS | cyclin-dependent kinase inhibitor 2B | CDKN2B | EARLY-DIAGNOSIS | PROLIFERATION | prognosis | RAF/MEK/ERK PATHWAY | BIOMARKERS | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | Sorafenib | RESISTANCE | hepatocellular carcinoma | PROGRESSION
Journal Article
Experimental and Therapeutic Medicine, ISSN 1792-0981, 01/2019, Volume 17, Issue 1, pp. 205 - 213
Cyclin dependent kinase inhibitor 2B (CDKN2B) encodes a cyclin-dependent kinase inhibitor that may enhance the formation of atherosclerotic plaques. The aim of... 
DNA methylation | Cyclin dependent kinase inhibitor 2B | Cardiovascular drug | Coronary heart disease | Estrogen | cardiovascular drug | MEDICINE, RESEARCH & EXPERIMENTAL | estrogen | PROMOTER METHYLATION | SEX | FOLLOW-UP | CANCER | cyclin dependent kinase inhibitor 2B | GENE | CARDIOVASCULAR-DISEASE | coronary heart disease | ASSOCIATION | ARTERY-DISEASE
Journal Article
Journal Article
Oncotarget, ISSN 1949-2553, 2016, Volume 7, Issue 35, pp. 57011 - 57020
Journal Article
Gene, ISSN 0378-1119, 03/2019
The long noncoding RNAs (lncRNAs) have gradually been reported to be an important class of RNAs with pivotal roles in the development and progression of... 
Journal Article
Oncotarget, ISSN 1949-2553, 09/2017, Volume 8, Issue 40, pp. 68721 - 68729
Hsa-miR-429 is increased in bladder cancer. Its roles in bladder cancer are poorly understood. The expression levels of hsa-miR-429 and cyclin-dependent kinase... 
Journal Article
Cell Cycle, ISSN 1538-4101, 06/2015, Volume 14, Issue 12, pp. 1908 - 1924
Abnormal proliferation is one characteristic of cancer-associated fibroblasts (CAFs), which play a key role in tumorigenesis and tumor progression. Oxidative... 
abnormal proliferation | cancer-associated fibroblasts | reactive oxygen species | breast cancer | redox homeostasis | proliferation signaling pathways | oxidized ATM | oxidative stress | Oxidized ATM | Cancer-associated fibroblasts | Oxidative stress | Reactive oxygen species | Proliferation signaling pathways | Redox homeostasis | Abnormal proliferation | Breast cancer | TRANSLOCATION | cyclin-dependent kinase inhibitor 2B | CAVEOLIN-1-DEFICIENT MICE | PHOSPHORYLATION | cyclin-dependent kinase 1 | E2F transcription factor 1 | cancer associated fibroblasts | CELL BIOLOGY | ataxia telangiectasia mutated | CCNB2 | CAFs | METABOLISM | E2F1 | WARBURG | cyclin A2 | normal fibroblasts | DSBs | CELLS | CDKN2B | double strand breaks | PROTEIN-KINASE | CCNA2 | NAC | N-acetyl-cysteine | ROS | CDK1 | ATM | NFs | tumor microenvironment | cyclin B2 | Cell Proliferation | Reactive Oxygen Species - metabolism | Antioxidants - chemistry | Ataxia Telangiectasia Mutated Proteins - metabolism | Oxidation-Reduction | Oxidative Stress | Signal Transduction | Humans | Homeostasis | MAP Kinase Kinase 1 - metabolism | Mitochondria - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | DNA Breaks, Double-Stranded | beta Catenin - metabolism | Breast Neoplasms - metabolism | Oxygen - chemistry | Cell Line, Tumor | Female | Proto-Oncogene Proteins c-akt - metabolism | Wnt Signaling Pathway | Fibroblasts - metabolism | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Oncology Letters, ISSN 1792-1074, 2014, Volume 8, Issue 4, pp. 1768 - 1774
MicroRNAs (miRs) function as key regulators of gene expression and their deregulation is associated with the carcinogenesis of various cancers. In the present... 
microRNA-31 | Cyclin-dependent kinase inhibitor 2B | microRNA-708 | Oncogene | Colorectal cancer | cyclin-dependent kinase inhibitor 2B | colorectal cancer | METASTASIS | oncogene | DROSOPHILA | COLON-CANCER | HEPATOCELLULAR-CARCINOMA | GENE | ONCOLOGY | GROWTH | TUMOR-SUPPRESSOR | PROMOTES | EXPRESSION
Journal Article
Experimental and Therapeutic Medicine, ISSN 1792-0981, 12/2017, Volume 14, Issue 6, pp. 6093 - 6098
Journal Article
Oncology Letters, ISSN 1792-1074, 04/2017, Volume 13, Issue 4, pp. 2115 - 2120
The aim of the present study was to investigate the association between methylation of cyclin-dependent kinase inhibitor 2B (CDKN2B) CpG islands and telomerase... 
Children | Acute lymphoblastic leukemia | Methylation | Cyclin-dependent kinase 4 inhibitor 2B | Telomerase | WILD-TYPE P53 | RNA | DOWN-REGULATION | cyclin-dependent kinase 4 inhibitor 2B | P15(INK4B) | CANCER | INACTIVATION | telomerase | ONCOLOGY | acute lymphoblastic leukemia | children | P15 | methylation | GENES | CELL-CYCLE | EXPRESSION
Journal Article
by Yang, JG and Liu, YC and He, AB and Liu, YH and Wu, JT and Liao, XH and Lv, ZJ and Wang, F and Mei, HB
ONCOTARGET, 09/2017, Volume 8, Issue 40, pp. 68721 - 68729
Background and Objectives: Hsa-miR-429 is increased in bladder cancer. Its roles in bladder cancer are poorly understood. Methods: The expression levels of... 
PATHOGENESIS | TARGET | cyclin-dependent kinase inhibitor 2B | urothelial carcinoma | GENE | microRNA | CARCINOMA | EXPRESSION | MIR-429 | CELL BIOLOGY
Journal Article
Diabetes Week, ISSN 1537-1425, 02/2017, p. 215
According to news reporting from Pisa, Italy, by NewsRx journalists, research stated, "The CDKN2A (p16) gene plays a key role in pancreatic cancer etiology.... 
Pancreatic cancer | Genes | Cyclin-dependent kinases | Cell cycle | Oncology | Diabetes | Kinases | Health risk assessment | Binding sites
Newspaper Article
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