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Cellular Microbiology, ISSN 1462-5814, 05/2011, Volume 13, Issue 5, pp. 717 - 730
NOD2 of the NLRs and TLR4 of the TLRs are major pattern-recognition receptors, which sense different microbial pathogens and have important roles in innate... 
Cyclooxygenase-2
Journal Article
PLoS ONE, 04/2013, Volume 8, Issue 4
Arbuscular mycorrhizal fungi (AMF) are common and important plant symbionts. They have coenocytic hyphae and form multinucleated spores. The nuclear genome of... 
Cyclooxygenase-2
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 2016, Volume 26, Issue 6, pp. 1516 - 1520
Cyclooxygenase-2 (COX-2) is the key enzyme in the prostaglandin synthesis pathway which is involved in various pathophysiological conditions. The enzyme is... 
Fluorous chemistry | Iodine-125 | Cyclooxygenase-2
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 03/2016, Volume 26, Issue 6, pp. 1516 - 1520
A novel I-containing trifluoro-pyrimidine compound ([ I]Pyricoxib) as potent and selective COX-2 inhibitor was prepared via radioiodo-destannylation reaction... 
Fluorous chemistry | Iodine-125 | Cyclooxygenase-2
Journal Article
Nanotoxicology, ISSN 1743-5390, 05/2018, Volume 12, Issue 5, pp. i - i
Journal Article
10/2013
Purpose: To investigate the effects and potential mechanisms of Shaoyao-Gangcao-Tang (SGT) on acute and resolution phases of carrageenin-induced pleurisy in... 
15-Deoxy-Δ12 | 14-PGJ2 | Shaoyao-Gangcao-Tang | Prostaglandin E2 | Inflammation | Cyclooxygenase-2
Web Resource
Food Research International, ISSN 0963-9969, 07/2018, Volume 109, pp. 350 - 357
α-Galacto-oligosaccharides have been reported to have beneficial health effects. The purpose of this study was to investigate the preventive effects of a newly... 
Colitis | Cyclooxygenase-2 | Anti-inflammatory | α-GOSg | anti-inflammatory | colitis | cyclooxygenase-2
Journal Article
Zaporozhye Medical Journal, ISSN 2306-4145, 07/2019, Volume 21, Issue 4, pp. 491 - 498
Hyperplastic processes of the endometrium without atypia have been an urgent problem for researchers around the world for a long time, given the current... 
endometrial hyperplasia | cyclooxygenase-2 | immunohistochemistry
Journal Article
Iatreia, ISSN 0121-0793, 01/2019, Volume 32, Issue 1, pp. 52 - 63
Journal Article
Natural Product Research, ISSN 1478-6419, 2018, pp. 1 - 10
Betulin (BE) is a pentacyclic triterpenes, obtained from natural sources and with several biological activities described, such as anti-tumoral and... 
derivatives | cytokines | Betulin | cytotoxicity | cyclooxygenase-2
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 10/2017, Volume 70, Issue 16, pp. C58 - C58
Heart functions were assessed by echocardiography and apoptotic cardiomyocytes were detected by TdT mediated dUTP Nick End Labeling (TUNEL) staining 24h after... 
Medicine, Chinese | Apoptosis | Cardiomyocytes | Inflammation | Cyclooxygenase-2 | Rodents
Journal Article
International Journal of Molecular Sciences, ISSN 1422-0067, 04/2019, Volume 20, Issue 7, p. 1771
Mechanical ventilation is usually required for saving lives in critically ill patients; however, it can cause ventilator-induced lung injury (VILI). As... 
ventilator-induced lung injury | Ly6Chigh monocytes | cyclooxygenase-2
Journal Article
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, ISSN 1073-449X, 10/2010, Volume 182, Issue 8, pp. 1020 - 1029
Rationale: Persistent inflammation plays a major role in chronic obstructive pulmonary disease (COPD) pathogenesis, but its mechanisms are incompletely... 
SMOKING-CESSATION | prostaglandin E-2, cyclooxygenase-2, fibroblasts | CYCLOOXYGENASE-2 | ALVEOLAR EPITHELIAL-CELLS | STABILITY | AIRWAY INFLAMMATION | miR-146a | PROLIFERATION | MESSENGER-RNA | RESPIRATORY SYSTEM | LUNG FIBROBLASTS | GEL CONTRACTION | EXPRESSION | chronic obstructive pulmonary disease | CRITICAL CARE MEDICINE
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2016, Volume 121, pp. 410 - 421
A new series of 2-substituted mercapto-4(3 )-quinazolinone were synthesized and assessed for anti-inflammatory and analgesic activities and inhibition of... 
Docking study | Synthesis | 2-Mercapto-4(3H)-quinazolinone | Cyclooxygenase-1/cyclooxygenase-2 inhibition assay | Anti-inflammatory activities | inhibition assay | Cyclooxygenase-1/cyclooxygenase-2 | SELECTIVE-INHIBITION | DESIGN | CHEMISTRY, MEDICINAL | CYCLOOXYGENASE-2 | ANALOGS | ANTITUMOR-ACTIVITY | DRUGS | BIOLOGICAL EVALUATION | DERIVATIVES | PROSTAGLANDIN SYNTHESIS | QUINAZOLINES | Analgesics - pharmacology | Analgesics - metabolism | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Cyclooxygenase 2 Inhibitors - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Analgesics - chemical synthesis | Cyclooxygenase 1 - chemistry | Cyclooxygenase 2 Inhibitors - metabolism | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Quinazolinones - pharmacology | Cyclooxygenase 2 Inhibitors - chemical synthesis | Chemistry Techniques, Synthetic | Cyclooxygenase 2 Inhibitors - pharmacology | Cyclooxygenase 2 - chemistry | Quinazolinones - chemical synthesis | Animals | Analgesics - chemistry | Cyclooxygenase 2 - metabolism | Protein Conformation | Mice | Molecular Docking Simulation | Quinazolinones - chemistry | Cyclooxygenase 1 - metabolism | Quinazolinones - metabolism | Drugstores | COX-2 inhibitors | Pharmacy | Diclofenac | Index Medicus
Journal Article
Asian Journal of Pharmaceutical and Clinical Research, ISSN 0974-2441, 2018, Volume 11, Issue 8, pp. 154 - 157
Journal Article
World Chinese Journal of Digestology, ISSN 1009-3079, 03/2017, Volume 25, Issue 8, pp. 702 - 708
Journal Article
Circulation Research, ISSN 0009-7330, 01/2009, Volume 104, Issue 2, pp. 228 - 235
Hypertension and vascular dysfunction result in the increased release of endothelium-derived contracting factors (EDCFs), whose identity is poorly defined. We... 
Aging | Aorta | Cyclooxygenase-2 | Thromboxane-prostanoid receptor | Endothelium-derived contracting factors
Journal Article
International Journal of Pharmacy and Pharmaceutical Sciences, 2016, Volume 8, Issue 7, pp. 399 - 403
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, ISSN 0363-6135, 03/2017, Volume 312, Issue 3, pp. H485 - H500
Vascular endothelial cells play an important role in the regulation of vascular function in response to mechanical stimuli in both healthy and diseased states.... 
glycocalyx | PECAM-1 | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | primary cilia | PROSTACYCLIN | INTEGRIN | cyclooxygenase-2 | syndecan-4 | SIGNAL-TRANSDUCTION | integrins | prostaglandin I-2 | shear stress | IN-VIVO | GENE-EXPRESSION | CYCLOOXYGENASE-2 EXPRESSION | PERIPHERAL VASCULAR DISEASE | HEPARAN-SULFATE PROTEOGLYCAN | EXTRACELLULAR-MATRIX | HEMODYNAMIC FORCES | FOCAL ADHESION KINASE
Journal Article
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