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ENDOCRINOLOGY, ISSN 0013-7227, 06/2003, Volume 144, Issue 6, pp. 2220 - 2228
The pleiotropic actions of angiotensin II are mediated by the primarily G. protein-coupled type I angiotensin (AT(1)) receptor. In this study a mutational... 
ADRENAL GLOMERULOSA CELLS | CARBOXYL-TERMINAL TAIL | M1 MUSCARINIC RECEPTOR | II TYPE-1 RECEPTOR | HORMONE RECEPTOR | AMINO-ACIDS | ALPHA(1B)-ADRENERGIC RECEPTOR | ENDOCRINOLOGY & METABOLISM | PROTEIN-COUPLED RECEPTORS | CYTOPLASMIC LOOP | CONSTITUTIVELY ACTIVE MUTANTS
Journal Article
BIOCHEMISTRY, ISSN 0006-2960, 10/2006, Volume 45, Issue 43, pp. 12976 - 12985
The CGRP(1) receptor exists as a heterodimeric complex between a single-pass transmembrane accessory protein ( RAMP1) and a family B G-protein-coupled receptor... 
SIGNAL-TRANSDUCTION | GENE-RELATED PEPTIDE | CYTOPLASMIC DOMAINS | ADENYLYL-CYCLASE | AMINO-ACIDS | BIOCHEMISTRY & MOLECULAR BIOLOGY | RHODOPSIN | PROTEIN-COUPLED RECEPTORS | LIGHT-DEPENDENT CHANGES | N-TERMINUS | ADRENOMEDULLIN
Journal Article
Journal Article
Journal Article
PLOS ONE, ISSN 1932-6203, 08/2010, Volume 5, Issue 8
Transforming growth factor-beta(1) (TGF-beta(1)) regulates cellular proliferation, differentiation, migration, and survival. The human TGF-beta(1) transcript... 
POSTTRANSCRIPTIONAL REGULATION | TGF-BETA-1 SYNTHESIS | SIGNALING PATHWAYS | FACTOR-BETA | NONCODING SEQUENCES | MULTIDISCIPLINARY SCIENCES | MESSENGER-RIBONUCLEOPROTEIN PARTICLES | PROXIMAL TUBULAR CELLS | SECONDARY STRUCTURE | CYTOPLASMIC MRNP | BINDING-PROTEINS
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 01/2008, Volume 324, Issue 1, pp. 196 - 205
We determined the functional role of a small domain in the third intracellular loop of the human muscarinic M-1 (hM(1)) receptor. Using site-directed... 
CHOLINERGIC-RECEPTOR | M-1 | CELLS | PALMITOYLATION | PHOSPHORYLATION | DOWN-REGULATION | PROTEIN-COUPLED RECEPTORS | CYTOPLASMIC LOOP | PHARMACOLOGY & PHARMACY | HIPPOCAMPAL-NEURONS | DOMAINS
Journal Article
CELLULAR SIGNALLING, ISSN 0898-6568, 01/2005, Volume 17, Issue 1, pp. 17 - 24
The vasoactive intestinal polypeptide (VIP) VPAC(1) receptor is preferentially coupled to Galphas protein that stimulates adenylate cyclase activity and also... 
CYTOPLASMIC DOMAIN | MUTAGENESIS | calcium | VASOACTIVE-INTESTINAL-PEPTIDE | SUBTYPES | ALPHA(1B)-ADRENERGIC RECEPTOR | INVOLVEMENT | PROTEIN-COUPLED RECEPTORS | ACTIVATING POLYPEPTIDE | AGONIST ACTIVITY | VPAC receptor | CELL BIOLOGY | adenylate cyclase | VIP | SELECTIVITY | IC3 loop
Journal Article
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, ISSN 1357-2725, 03/2009, Volume 41, Issue 3, pp. 677 - 686
The II-III loop of the dihydropyridine receptor (DHPR) alpha(1S) subunit is a modulator of the ryanodine receptor (RyR1) Ca2+ release channel in vitro and is... 
ACTIVATION | Protein-protein interaction | DHPR | CA2+ RELEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | II-III-LOOP | RyR | Intrinsically unstructured protein | MAUROCALCINE | PEPTIDE | SCORPION TOXINS | CELL BIOLOGY | NMR | IMPERATOXIN-A | SEQUENCE | CYTOPLASMIC LOOP | C-REGION
Journal Article
Biological Chemistry, ISSN 1431-6730, 2001, Volume 382, Issue 11, pp. 1551 - 1558
Journal Article
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, 01/2009, Volume 284, Issue 4, pp. 2023 - 2030
The Cys loop receptor channels mediate fast synaptic transmission in the nervous system. The M2-demarcated transmembrane pore is an important determinant of... 
CONDUCTANCE | ANGSTROM RESOLUTION | LARGE CYTOPLASMIC LOOP | 5-HT3 RECEPTOR | DETERMINANTS | GATING MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | NICOTINIC ACETYLCHOLINE-RECEPTOR | 5-HYDROXYTRYPTAMINE TYPE-3 | SELECTIVITY | SUBUNIT
Journal Article
The FEBS Journal, ISSN 1742-464X, 07/2016, Volume 283, Issue 13, pp. 2458 - 2475
The cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel is activated by ATP binding‐induced dimerization of nucleotide‐binding domains,... 
extracellular loop | metal disturbance | ABC transporter | long‐range gating coupling | intracellular loop | long-range gating coupling | DOMAIN | PROTEIN | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | NUCLEOTIDE-BINDING | CYTOPLASMIC LOOP 3 | ZINC | PORE | ARCHITECTURE | CFTR CHLORIDE CHANNEL | Cystic fibrosis | Cysteine | Cystine | Spices | Mutation | Molecular biology | Rodents
Journal Article
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