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YAKUGAKU ZASSHI, ISSN 0031-6903, 2015, Volume 135, Issue 4, pp. 567 - 578
Animal experiments cannot predict the probability of idiosyncratic drug toxicity; consequently, an important goal of the pharmaceutical industry is to develop... 
idiosyncratic toxicity | covalent protein binding | cytotoxic T lymphocyte | chemically reactive metabolite | judging criteria | gene biomarker
Journal Article
日本医科大学医学会雑誌, ISSN 1349-8975, 2017, Volume 13, Issue 3, pp. 140 - 144
「はじめに:丸山ワクチンとその本体」本論文の主題である「丸山ワクチン」はどのようなものなのであろう. このワクチン開発に心血を注がれた日本医科大学皮膚科学主任教授であった故丸山千里博士は, 戦中・戦後を通じて皮膚結核の大家として多くの患者の診察に忙殺されていた中で, 皮膚結核に罹患した患者において癌の進行が遅いこと,... 
immunogenic DCs | CD1 | cross-presentation | tolerogenic DCs (dendritic cells) | CTL (cytotoxic T lymphocytes)
Journal Article
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, ISSN 0031-6903, 04/2015, Volume 135, Issue 4, pp. 567 - 578
Journal Article
Drug Delivery System, ISSN 0913-5006, 2013, Volume 28, Issue 1, pp. 35 - 44
養子免疫療法は、癌患者より採取したCD8+ T細胞から腫瘍特異的な細胞傷害性T細胞 (CTL)... 
Gene transduction | Cytotoxic T-lymphocytes | Tumor vessel-targeting | Adoptive immunotherapy | Chimeric antigen-receptor
Journal Article
Biological & Pharmaceutical Bulletin, ISSN 0918-6158, 2007, Volume 30, Issue 10, pp. 1913 - 1917
Cytotoxic T-lymphocyte antigen 4-immunoglobulin (CTLA4Ig) has immunosuppressive activity and the ability to induce immune tolerance. There has been no report... 
Journal Article
臨床神経学, ISSN 0009-918X, 2012, Volume 52, Issue 11, pp. 1234 - 1236
Behçet disease and Sweet disease are multisystem inflammatory disorders involving mucocutaneous tissue as well as nervous system (neuro-Behçet disease and... 
神経スウィート病 | ヒト白血球型抗原 | 神経ベーチェット病 | 細胞障害性Tリンパ球
Journal Article
Drug Delivery System, ISSN 0913-5006, 2012, Volume 27, Issue 3, pp. 194 - 201
Journal Article
Journal of Health Science, ISSN 1344-9702, 2010, Volume 56, Issue 1, pp. 41 - 46
To test for the role of cytotoxic T-lymphocyte associated antigen 4 (CTLA4) +49A/G and tumor necrosis factor alpha (TNF-α) -308G/A polymorphisms in the... 
Journal Article
臨床神経学, ISSN 0009-918X, 2011, Volume 51, Issue 11, pp. 1044 - 1046
HTLV-I is a human retrovirus and causes adult T cell leukemia and several inflammatory diseases such as HAM/TSP. The infection occurs via HTLV-I-infected cells... 
HTLV-I | HAM | プロウイルス量 | bystander damage | 細胞傷害性Tリンパ球
Journal Article
Drug Delivery System, ISSN 0913-5006, 2010, Volume 25, Issue 1, pp. 46 - 51
Journal Article
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, ISSN 0031-6903, 2007, Volume 127, Issue 2, pp. 293 - 300
Journal Article
Biological & Pharmaceutical Bulletin, ISSN 0918-6158, 2004, Volume 27, Issue 3, pp. 404 - 406
When hot-water extracts of mushroom Agaricus brazei MURRILL fruiting bodies (Agaricus extracts) were administered orally into Meth A-bearing mice, tumor growth... 
Journal Article
日本ハンセン病学会雑誌, ISSN 1342-3681, 2009, Volume 78, Issue 3, pp. 271 - 276
The role of vaccines to tuberculosis and leprosy is to induce a cellular immunity, and as a result to induce the differentiation of memory CD8+ cytotoxic T... 
ワクチン | 樹状細胞 | Th1 細胞 | ペプチド | 細胞傷害性T細胞
Journal Article
Inflammation and Regeneration, ISSN 1880-9693, 2015, Volume 35, Issue 5, pp. 220 - 225
Cytotoxic T lymphocytes (CTLs) represent the most promising therapeutic avenue in cancer immunotherapy, yet most of the currently ongoing trials utilizing CTLs... 
melanoma | induced pluripotent stem cells (iPSCs) | Cytotoxic T lymphocytes (CTLs) | MART-1 | cloning
Journal Article
Journal of the Mass Spectrometry Society of Japan, ISSN 1340-8097, 2006, Volume 54, Issue 3, pp. 75 - 80
We have studied human tumor antigens applicable for a wide variety of tumors, and determined immunogenic peptide epitopes from these tumor antigen molecules... 
Cross-presentation | Heat shock proteins | Cancer vaccine | HLA | Cytotoxic T lymphocytes
Journal Article
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