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JOURNAL OF MOLECULAR BIOLOGY, ISSN 0022-2836, 08/2018, Volume 430, Issue 17, pp. 2670 - 2676
Aminoacyl-tRNA-synthetases are crucial enzymes for initiation step of translation. Possessing editing activity, they protect living cells from misincorporation... 
D-AMINO ACIDS | SYNTHETASES | RECOGNITION | D-TYR-TRNA(TYR) DEACYLASE | YBAK PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | PROTEIN-SYNTHESIS | D-aminoacyl-tRNA-deacylase | BACILLUS-SUBTILIS | aminoacyl-tRNA synthetase | D-Tyr | EDITING DOMAIN | mistranslation | tRNA(Tyr) | AMINOACYLATION
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 08/2018, Volume 430, Issue 17, pp. 2670 - 2676
Aminoacyl-tRNA-synthetases are crucial enzymes for initiation step of translation. Possessing editing activity, they protect living cells from misincorporation... 
mistranslation | d-Tyr | d-aminoacyl-tRNA-deacylase | aminoacyl-tRNA synthetase | tRNATyr | D-aminoacyl-tRNA-deacylase | tRNA | D-Tyr
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 02/2018, Volume 496, Issue 3, pp. 891 - 897
Sirtuins (SIRT1–7) are NAD -dependent deacetylase/deacylases that regulate a wide variety of biological functions. Although the roles of sirtuins in cartilage... 
Deacylase | SIRT7 | SOX9 | Chondrocyte | Osteoarthritis | Sirtuin | CHONDROCYTES | BIOCHEMISTRY & MOLECULAR BIOLOGY | SIRTUINS | INHIBITION | BIOPHYSICS | DEACETYLATION | METABOLISM | GENE-EXPRESSION
Journal Article
Infection and Immunity, ISSN 0019-9567, 10/2018, Volume 86, Issue 10
Journal Article
JOURNAL OF PHYSICAL CHEMISTRY B, ISSN 1520-6106, 01/2018, Volume 122, Issue 3, pp. 1092 - 1101
Archaeal threonyl-tRNA synthetase (ThrRS) possesses an editing active site wherein tRNA(Thr) that has been misaminoacylated with serine (i.e., Ser-tRNA(Thr))... 
COMPUTATIONAL ENZYMOLOGY | MOLECULAR-DYNAMICS | PROTEIN | MECHANISM | SUBSTRATE | PEPTIDE-BOND FORMATION | CHEMISTRY, PHYSICAL | TRANSLATIONAL QUALITY-CONTROL | RELEASE | RIBOSOME | DEACYLASE
Journal Article
Cell Metabolism, ISSN 1550-4131, 04/2017, Volume 25, Issue 4, pp. 838 - 855.e15
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 02/2019, Volume 476, Issue 4, pp. 719 - 732
D-aminoacyl-tRNA-deacylase (DTD) prevents the incorporation of o-amino acids into proteins during translation by hydrolyzing the ester bond between mistakenly... 
RIBONUCLEIC-ACID SYNTHETASES | ENZYME | SPECIFICITY | D-TYR-TRNA(TYR) DEACYLASE | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | PURIFICATION | GEOMETRY OPTIMIZATION | QUALITY-CONTROL | NEUTRAL HYDROLYSIS
Journal Article
Chemical Reviews, ISSN 0009-2665, 09/2018, Volume 118, Issue 17, pp. 8188 - 8241
Journal Article
Scientific Reports, ISSN 2045-2322, 03/2017, Volume 7, Issue 1
The antimicrobial peptide KLKLLLLLKLK-NH2 was developed based on sapesin B, and synthesized using D-amino acids. Biochemical properties of the D-form and... 
IMMUNE-RESPONSE | OUTER-MEMBRANE | PEREGRINA FLESH FLY | ANTIBACTERIAL PROTEIN | SALMONELLA-ENTERICA | MULTIDISCIPLINARY SCIENCES | DEACYLASE PAGL | STAPHYLOCOCCUS-AUREUS | SARCOPHAGA-PEREGRINA | CATIONIC PEPTIDES | POLYMYXIN-B
Journal Article
Methods, ISSN 1046-2023, 01/2017, Volume 113, pp. 3 - 12
Aminoacyl-tRNA synthetases play a central role in protein synthesis, catalyzing the attachment of amino acids to their cognate tRNAs. Here, we describe a... 
Cyclodipeptide synthase | High-throughput screen | Spectrophotometric assay | Post-transfer editing | d-tyrosyltRNA deacylase | Aminoacyl-tRNA synthetase | D-tyrosyltRNA deacylase | INFECTIONS | D-TYR-TRNA(TYR) DEACYLASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | BIOCHEMICAL RESEARCH METHODS | SYNTHETASE INHIBITOR | COUPLED ENZYME ASSAYS | SACCHAROMYCES-CEREVISIAE | CLOSTRIDIUM-DIFFICILE | IN-VITRO | NONRIBOSOMAL PEPTIDE-SYNTHESIS | CYCLODIPEPTIDE SYNTHASES | Stereoisomerism | Aminoacyltransferases - genetics | Geobacillus stearothermophilus - genetics | RNA, Transfer, Tyr - genetics | Sensitivity and Specificity | Tyrosine-tRNA Ligase - metabolism | Adenosine Monophosphate - biosynthesis | NAD - metabolism | Recombinant Proteins - metabolism | Transfer RNA Aminoacylation | Gene Expression | Geobacillus stearothermophilus - enzymology | Escherichia coli - enzymology | RNA, Transfer, Tyr - metabolism | Enzyme Assays | Recombinant Proteins - genetics | Tyrosine-tRNA Ligase - genetics | Peptides, Cyclic - biosynthesis | Hydrolysis | Tyrosine - metabolism | Escherichia coli - genetics | Mycobacterium tuberculosis - enzymology | Aminoacyltransferases - metabolism | Kinetics | Spectrophotometry | Mycobacterium tuberculosis - genetics | Aminoacyl-tRNA synthetases | Transfer RNA | Tyrosine | Protein biosynthesis | Recycling (Waste, etc.)
Journal Article