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index medicus (222) 222
animals (168) 168
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ouabain (99) 99
hypertension (84) 84
sodium-potassium-exchanging atpase - antagonists & inhibitors (81) 81
male (76) 76
digitalis-like-factor (75) 75
rats (72) 72
digoxin (70) 70
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pharmacology & pharmacy (57) 57
sodium-potassium-exchanging atpase - metabolism (55) 55
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biochemistry & molecular biology (48) 48
cardenolides (48) 48
ouabain - metabolism (47) 47
peripheral vascular disease (47) 47
human plasma (45) 45
chromatography, high pressure liquid (40) 40
ouabain - pharmacology (39) 39
digitalis-like factor (38) 38
endogenous ouabain (37) 37
blood-pressure (35) 35
digitalis-like factors (35) 35
essential-hypertension (35) 35
ouabain - blood (32) 32
compound (31) 31
identification (31) 31
sodium (31) 31
human-plasma (30) 30
na+,k+-atpase (30) 30
bovine adrenocortical-cells (29) 29
cardiac glycosides (28) 28
enzyme inhibitors - pharmacology (27) 27
na+/k+-atpase (27) 27
neurosciences (27) 27
cattle (26) 26
blood pressure (25) 25
na,k-atpase (25) 25
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adult (24) 24
hypertension - physiopathology (23) 23
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sodium pump (23) 23
bufanolides - pharmacology (22) 22
inhibitor (21) 21
marinobufagenin (21) 21
medicine, research & experimental (21) 21
plasma (21) 21
radioimmunoassay (21) 21
rats, sprague-dawley (21) 21
dose-response relationship, drug (20) 20
inhibition (20) 20
na (20) 20
physiology (20) 20
saponins (20) 20
adenosine triphosphatase (19) 19
blood pressure - drug effects (19) 19
na+-k+-atpase (19) 19
cardiotonic steroids (18) 18
pump (18) 18
cell biology (17) 17
endocrinology & metabolism (17) 17
hypertension - metabolism (17) 17
k (17) 17
saponins - blood (17) 17
bufanolides - metabolism (16) 16
cardiac glycosides - pharmacology (16) 16
digitalis-like substance (16) 16
in vitro techniques (16) 16
na+ (16) 16
ouabain - immunology (16) 16
physiological aspects (16) 16
pregnancy (16) 16
rats, wistar (16) 16
bovine hypothalamus (15) 15
cardiac glycosides - metabolism (15) 15
endogenous digitalis-like factor (15) 15
purification (15) 15
steroids (15) 15
digoxin - immunology (14) 14
enzyme-linked immunosorbent assay (14) 14
heart (14) 14
inhibitors (14) 14
k+-atpase (14) 14
natriuretic hormone (14) 14
sodium - metabolism (14) 14
cardiac-glycosides (13) 13
cells (13) 13
mass spectrometry (13) 13
serum (13) 13
cross reactions (12) 12
enzyme inhibitors - metabolism (12) 12
hypertension - blood (12) 12
sodium-potassium-exchanging atpase - physiology (12) 12
structural-analysis (12) 12
biology (11) 11
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Journal Article
Journal Article
Journal Article
Journal of carcinogenesis, ISSN 1477-3163, 2012, Volume 11, Issue 1, pp. 2 - 2
Since their first discovery as potential anti-cancer drugs decades ago, there is increasing evidence that digitalis-like compounds (DLC) have anti-tumor... 
Adrenal exhaustion | stress | endogenous digitalis-like compounds | Na/K-ATPase | isoforms | threshold | tumorigenesis
Journal Article
JOURNAL OF PSYCHIATRIC RESEARCH, ISSN 0022-3956, 08/2019, Volume 115, pp. 21 - 28
Na+, K+-ATPase is an essential membrane transporter. In the brain, the alpha 3 isoform of Na+, K+-ATPase is vital for neuronal function. The enzyme and its... 
DIGITALIS-LIKE COMPOUNDS | SODIUM-PUMP | PSYCHIATRY | ENDOGENOUS CARDIAC STEROIDS | SCHIZOPHRENIA | BIPOLAR DISORDER | RAPID-ONSET | EXPRESSION | BRAIN | INTERNEURONS | PATHOPHYSIOLOGY
Journal Article
Brain Research Bulletin, ISSN 0361-9230, 03/2018, Volume 137, pp. 356 - 362
Bipolar disorder (BD) is a severe mental illness characterized by episodes of mania and depression. Numerous studies have implicated the involvement of... 
Mania | Oxidative stress | Bipolar disorder | Amphetamine | Cardiac steroids | Ouabain | HYPERLOCOMOTION | DOPAMINE RELEASE | SUBSTANCES | NEUROSCIENCES | DIGITALIS-LIKE COMPOUNDS | ANTIOXIDANT | ANIMAL-MODELS | NA+,K+-ATPASE | LITHIUM | Index Medicus
Journal Article
Canadian Journal of Physiology and Pharmacology, ISSN 0008-4212, 1/2010, Volume 88, Issue 1, pp. 38 - 44
Journal Article
RSC Advances, ISSN 2046-2069, 2016, Volume 6, Issue 96, pp. 93832 - 93841
Two new 19-norbufadienolides (1 and 2), one new 14,15-epoxy bufadienolide (3), and eight rare bufadienolide-fatty acid conjugates (4-11), together with four... 
FATTY-ACID ESTERS | MARINUS | VENOM | DIGITALIS-LIKE COMPOUNDS | PLASMA | CRYSTAL-STRUCTURE | SKIN | IDENTIFICATION | CHEMISTRY, MULTIDISCIPLINARY | CHEMICAL DEFENSES | C-23 STEROIDS
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 12/2009, Volume 297, Issue 6, pp. 2026 - 2034
Endogenous ouabain (EO)-like compounds are synthesized in and released from the adrenal gland. Although EO has been implicated in several pathological states... 
Vascular reactivity | Sodium homestasis | Cardiac glycosides | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | vascular reactivity | GLYCOSIDE BINDING-SITE | PLASMA-RENIN | cardiac glycosides | BLOOD-PRESSURE | NA+-K+-ATPASE | NATRIURETIC RESPONSE | INDUCED HYPERTENSION | BIOLOGICAL SIGNIFICANCE | DIGITALIS-LIKE COMPOUNDS | CARDIAC STEROIDS | SODIUM-PUMP | PERIPHERAL VASCULAR DISEASE | sodium homestasis | Blood Pressure | Rats, Wistar | Adrenal Cortex - metabolism | Homeostasis | Male | Sodium - metabolism | Vasodilation | Dose-Response Relationship, Drug | Cardenolides - immunology | Saponins - blood | Kidney - metabolism | Phenylephrine - pharmacology | Time Factors | Aorta, Thoracic - drug effects | Corticosterone - blood | Weight Gain | Cardenolides - blood | Vasoconstrictor Agents - pharmacology | Rabbits | Atrial Natriuretic Factor - metabolism | Aldosterone - blood | Aorta, Thoracic - metabolism | Rats | Saponins - immunology | Vasoconstriction - drug effects | Antibodies - administration & dosage | Sodium-Potassium-Exchanging ATPase - metabolism | Animals | Infusions, Intravenous | Natriuresis | Prevention | Usage | Rattus | Ouabain | Physiological aspects | Models | Research | Cardiovascular diseases | Natriuretic peptides | Plasma | Immunoglobulins | Protein synthesis | Rodents | Coronary vessels | Physiology | Chemical compounds | Index Medicus
Journal Article