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dihydroouabain (27) 27
animals (17) 17
index medicus (17) 17
ouabain - analogs & derivatives (11) 11
ouabain - pharmacology (11) 11
guinea pigs (9) 9
calcium - metabolism (8) 8
pharmacology & pharmacy (8) 8
male (7) 7
female (6) 6
in vitro techniques (6) 6
myocardium - metabolism (6) 6
ouabain (5) 5
sodium - metabolism (5) 5
cardiac & cardiovascular systems (4) 4
muscle (4) 4
myocardial contraction - drug effects (4) 4
myocardium - cytology (4) 4
action potential duration (3) 3
cell biology (3) 3
coronary perfusion (3) 3
cromakalim (3) 3
dose-response relationship, drug (3) 3
enzyme inhibitors - pharmacology (3) 3
fura-2 (3) 3
glibenclamide (3) 3
glycosides (3) 3
guinea-pig (3) 3
heart ventricles - cytology (3) 3
heart ventricles - drug effects (3) 3
heart ventricles - metabolism (3) 3
ischemia (3) 3
isoproterenol (3) 3
membrane potentials - drug effects (3) 3
metabolic inhibition (3) 3
nuclear-magnetic-resonance (3) 3
patch-clamp (3) 3
patch-clamp techniques (3) 3
potassium (3) 3
rana pipiens (3) 3
sodium (3) 3
ventricular muscle (3) 3
biological transport - physiology (2) 2
biological transport, active (2) 2
calcium - pharmacokinetics (2) 2
cell membrane - drug effects (2) 2
cells (2) 2
cells, cultured (2) 2
confocal microscopy (2) 2
contraction (2) 2
dogs (2) 2
electrophysiology (2) 2
fibers (2) 2
fluorescent dyes (2) 2
grayanotoxin-i (2) 2
guinea-pig heart (2) 2
heart - drug effects (2) 2
heart, guinea-pig (2) 2
humans (2) 2
immunohistochemistry (2) 2
intracellular calcium (2) 2
inversion recovery method (2) 2
ion activity (2) 2
ischemia-reperfusion injury (2) 2
isoproterenol - pharmacology (2) 2
k (2) 2
medicine, research & experimental (2) 2
mitochondria, heart - ultrastructure (2) 2
myocardial contraction - physiology (2) 2
myocardium - pathology (2) 2
myocytes (2) 2
myocytes, cardiac - drug effects (2) 2
myocytes, cardiac - metabolism (2) 2
na (2) 2
na+/k+ pump (2) 2
na/k pump (2) 2
neurosciences (2) 2
nitric oxide - metabolism (2) 2
nitric oxide donors - pharmacology (2) 2
osmolar concentration (2) 2
pig ventricular myocytes (2) 2
pimobendan (2) 2
positive inotropic effect (2) 2
potassium - pharmacology (2) 2
pump (2) 2
purkinje fibers - physiology (2) 2
rats (2) 2
skin (2) 2
sodium-potassium-exchanging atpase - antagonists & inhibitors (2) 2
sodium-potassium-exchanging atpase - drug effects (2) 2
sodium-potassium-exchanging atpase - physiology (2) 2
stimulation (2) 2
tetrodotoxin - pharmacology (2) 2
time factors (2) 2
i (1) 1
acetamides - metabolism (1) 1
acetamides - pharmacology (1) 1
acidosis (1) 1
acidosis - metabolism (1) 1
acidosis positive inotropic effect intact canine ventricular muscle myofilament ca2+ sensitivity levosimendan dihydroouabain (1) 1
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Journal Article
Journal Article
Journal Article
BIPOLAR DISORDERS, ISSN 1398-5647, 06/2007, Volume 9, pp. 35 - 36
Conference Proceeding
European Journal of Pharmacology, ISSN 0014-2999, 1999, Volume 380, Issue 1, pp. 37 - 48
In guinea-pig myocardial mitochondria preparation, lowering the Ca concentration or pH level in the perfusate rapidly elevated the fura-2 Ca signal ([Ca ](m)).... 
Ischemia-reperfusion injury | Endothelial nitric oxide (NO·) synthase | Reactive oxygen species | Guinea pig | Nitric oxide (NO·) | EPR (Electron paramagnetic resonance) spectrometry | Myocardial mitochondria | Nitric oxide (NO.) | Endothelial nitric oxide (NO.) synthase | DIHYDROOUABAIN | guinea pig | SUPEROXIDE | OXYGEN RADICALS | endothelial nitric oxide (NO center dot) synthase | nitric oxide (NO center dot) | NUCLEAR-MAGNETIC-RESONANCE | RAT-LIVER MITOCHONDRIA | myocardial mitochondria | ischemia-reperfusion injury | INFARCT SIZE | HEART | CA2 | reactive oxygen species | L-ARGININE | PHARMACOLOGY & PHARMACY | DYSFUNCTION | EPR (electron paramagnetic resonance) spectrometry | Free Radical Scavengers - pharmacology | Immunohistochemistry | Mitochondria, Heart - ultrastructure | Mitochondria, Heart - metabolism | Reactive Oxygen Species - metabolism | Calcium - metabolism | Humans | Nitric Oxide Synthase - antagonists & inhibitors | Nitric Oxide Synthase - physiology | Immunoblotting | Male | Penicillamine - analogs & derivatives | Myocardial Reperfusion Injury - enzymology | Nitrates - chemistry | Spin Trapping | Free Radicals - metabolism | Female | Nitric Oxide Donors - pharmacology | NG-Nitroarginine Methyl Ester - pharmacology | Nitric Oxide Synthase - ultrastructure | Guinea Pigs | Superoxide Dismutase - pharmacology | Electron Spin Resonance Spectroscopy | Penicillamine - pharmacology | Enzyme Inhibitors - pharmacology | Hydrogen Peroxide - pharmacology | Mitochondria, Heart - enzymology | Nitric Oxide Synthase Type III | Myocardium - pathology | Myocardium - cytology | Myocardium - enzymology | Animals | Arginine - pharmacology | Heart - drug effects | Free Radicals - pharmacology | Calcium - pharmacokinetics | Nitric Oxide - metabolism | Myocardial Reperfusion Injury - prevention & control | Hydrogen-Ion Concentration | Index Medicus
Journal Article
Journal Article
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, ISSN 0022-2828, 03/1999, Volume 31, Issue 3, pp. 533 - 542
The Na+-K+ pump is a consumer of intracellular ATP. We therefore examined whether blockade of the Na+-K+ pump by cardiac glycosides could inhibit ATP-sensitive... 
SENSITIVE POTASSIUM CHANNELS | CARDIAC & CARDIOVASCULAR SYSTEMS | STIMULATION | coronary perfusion | action potential duration | MEMBRANE PATCHES | MYOCYTES | K-ATP channel | ventricular muscle | patch-clamp | Na+-K+ pump current | cromakalim | CARDIAC-CELLS | ischemia | CELL BIOLOGY | guinea-pig | dihydroouabain | glibenclamide | metabolic inhibition
Journal Article
Journal of Cardiovascular Pharmacology, ISSN 0160-2446, 10/2001, Volume 38, Issue 4, pp. 593 - 605
Effects of FK409 were investigated in perfused guinea-pig Langendorff hearts subjected to ischemia and reperfusion. Nitric oxide electrode, fluorometry, and P... 
Ischemia-reperfusion | fluorometry | Nitric oxide electrode | FK409 | St. Thomas' Hospital solution | P nuclear magnetic resonance | Ca | Left ventricular developed pressure | DIHYDROOUABAIN | Ca2+ fluorometry | CARDIAC & CARDIOVASCULAR SYSTEMS | PEROXYNITRITE | NUCLEAR-MAGNETIC-RESONANCE | INTRACELLULAR PH | nitric oxide electrode | ischemia-reperfusion | ISCHEMIA-REPERFUSION INJURY | SYNTHASE | left ventricular developed pressure | CALCIUM | P-31 nuclear magnetic resonance | OXYGEN-FREE RADICALS | PHARMACOLOGY & PHARMACY | CARDIAC MITOCHONDRIA | FAILING MYOCARDIUM | Mitochondria, Heart - ultrastructure | Nitric Oxide Donors - chemistry | Calcium - metabolism | Mitochondria, Heart - pathology | Nitro Compounds - chemistry | Male | Fluorometry | Myocardial Reperfusion Injury - pathology | Nitro Compounds - therapeutic use | Myocardium - metabolism | Myocardial Ischemia - physiopathology | Nitro Compounds - pharmacology | Female | Blood Pressure - drug effects | Nitric Oxide Donors - therapeutic use | Myocardial Reperfusion Injury - drug therapy | Nitric Oxide Donors - pharmacology | Myocardium - ultrastructure | Guinea Pigs | Myocardial Ischemia - prevention & control | Myocardium - pathology | Fura-2 - metabolism | Myocardial Ischemia - pathology | Myocardial Reperfusion Injury - metabolism | Animals | Calcium Signaling - drug effects | Actin Cytoskeleton - pathology | Actin Cytoskeleton - ultrastructure | In Vitro Techniques | Nitric Oxide - metabolism | Blood Flow Velocity - drug effects | Index Medicus
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 1995, Volume 282, Issue 1, pp. 121 - 130
Journal Article
Acta Physiologica Sinica, ISSN 0371-0874, 10/2002, Volume 54, Issue 5, pp. 385 - 389
Journal Article
MOLECULAR AND CELLULAR BIOCHEMISTRY, ISSN 0300-8177, 10/1994, Volume 139, Issue 1, pp. 59 - 70
The effects of the cardiac glycoside dihydroouabain (DHO), and the ericaceous toxin grayanotoxin-I (GTX-I) on myocardial cellular sodium (Na-i) concentrations... 
DIHYDROOUABAIN | NA-23 NMR | FROG-HEART | NUCLEAR-MAGNETIC-RESONANCE | INTRACELLULAR SODIUM | CHEMICAL-SHIFT | GUINEA-PIG HEART | SALIVARY-GLAND | CELL BIOLOGY | RAT HEARTS | GRAYANOTOXIN-I | RELAXATION-TIMES | POTASSIUM | INVERSION RECOVERY METHOD | ION ACTIVITY | CHANNEL ACTIVATORS
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 1993, Volume 25, Issue 6, pp. 707 - 720
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0002-9513, 1990, Volume 259, Issue 2, pp. H488 - H496
Na-K pump current (Ipump) is a function of the intracellular Na+ concentration [( Na+]i). We examined the quantitative relationship between Ipump and [Na+]i in... 
voltage clamp | dihydroouabain | electrogenic pump current | internal sodium | PHYSIOLOGY | Animals | Guinea Pigs | Osmolar Concentration | Myocardium - metabolism | Potassium Channels - physiology | Electrophysiology | Sodium Channels - physiology | Sodium - metabolism | Myocardium - cytology | Index Medicus
Journal Article
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