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1. Full Text Epistasis in protein evolution
by Starr, Tyler N and Thornton, Joseph W
Protein Science, ISSN 0961-8368, 07/2016, Volume 25, Issue 7, pp. 1204 - 1218
The structure, function, and evolution of proteins depend on physical and genetic interactions among amino acids. Recent studies have used new strategies to... 
ancestral sequence reconstruction | epistasis | protein evolution | deep mutational scanning | evolutionary biochemistry | sequence space | sequence‐function relationship | sequence-function relationship | SPECIFICITY | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | TEM-1 BETA-LACTAMASE | REGULATORY EVOLUTION | DIRECTED EVOLUTION | FITNESS LANDSCAPES | RESIDUE COEVOLUTION | GLUCOCORTICOID-RECEPTOR EVOLUTION | MUTATIONS | Proteins - genetics | Cell Lineage | Computational Biology - methods | Proteins - metabolism | Epistasis, Genetic | Humans | Selection, Genetic | Protein Binding | Mutation | Proteins - chemistry | Binding Sites | Evolution, Molecular | Proteins | Genetic research | Physiological aspects | Evolution | Reviews | Review
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2. Full Text Synthetic evolution
by Simon, Anna J and d’Oelsnitz, Simon and Ellington, Andrew D
Nature Biotechnology, ISSN 1087-0156, 2019, Volume 37, Issue 7, pp. 730 - 743
The combination of modern biotechnologies such as DNA synthesis, lambda red recombineering, CRISPR-based editing and next-generation high-throughput sequencing... 
RANDOM MUTAGENESIS | CONTINUOUS DIRECTED EVOLUTION | SUBSTRATE-SPECIFICITY | IN-VITRO EVOLUTION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | REVERSE-TRANSCRIPTASE | ETHANOL TOLERANCE | HYBRID ENZYMES | TRANSCRIPTION MACHINERY | DNA-REPLICATION | PROTOPLAST FUSION | Nucleotide sequencing | Adaptation (Biology) | Observations | Methods | DNA sequencing | CRISPR | Phenotypes | Genes | Biological evolution | Genomes | Natural selection | Gene sequencing | DNA biosynthesis | Next-generation sequencing | Evolution | Mutation | Throwing | Deoxyribonucleic acid--DNA | Fitness
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3. Full Text Adaptive laboratory evolution — harnessing the power of biology for metabolic engineering
by Portnoy, Vasiliy A and Bezdan, Daniela and Zengler, Karsten
Current Opinion in Biotechnology, ISSN 0958-1669, 2011, Volume 22, Issue 4, pp. 590 - 594
Highlights ► Adaptive laboratory evolution (ALE) as a tool for metabolic engineering. ► Latent pathway activation by ALE. ► ALE has successfully been used to... 
Internal Medicine | COLI K-12 MG1655 | YEAST | PATHWAY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ESCHERICHIA-COLI | GROWTH | ADAPTATION | BIOCHEMICAL RESEARCH METHODS | STRESS | SACCHAROMYCES-CEREVISIAE | DIRECTED EVOLUTION | TRANSCRIPTOME ANALYSIS | Saccharomyces cerevisiae - metabolism | Directed Molecular Evolution | Metabolic Networks and Pathways | Escherichia coli - genetics | Saccharomyces cerevisiae - genetics | Escherichia coli - metabolism | Beer
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4. Full Text Exploiting evolution
by Ashe, Kathryn and Ashe, Kathryn
Nature Chemistry, ISSN 1755-4330, 12/2018, Volume 10, Issue 12, pp. 1173 - 1173
CHEMISTRY, MULTIDISCIPLINARY | Proteins - genetics | Chemistry | Nobel Prize | Proteins - metabolism | Humans | Directed Molecular Evolution | Genetic Variation - genetics | Proteins - chemistry
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5. The evolution of self-help
by Archibald, Matthew
2007, 1st ed., ISBN 9780230600379, xiii, 187
history | Self-help techniques | Self Care | Self-Help Groups | History, 20th Century
Book
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6. Directed evolution library creation
: methods and protocols
by Gillam, Elizabeth M. J and Copp, Janine N and Ackerley, David F
2014, Second edition., Methods in molecular biology, ISBN 9781493910533, Volume 1179
Combinatorial Chemistry Techniques | Gene Library | Directed Molecular Evolution
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7. Full Text Methods for the directed evolution of proteins
by Packer, Michael S and Liu, David R
Nature Reviews Genetics, ISSN 1471-0056, 07/2015, Volume 16, Issue 7, pp. 379 - 394
Directed evolution has proved to be an effective strategy for improving or altering the activity of biomolecules for industrial, research and therapeutic... 
RANDOM MUTAGENESIS | GREEN FLUORESCENT PROTEIN | TRANSFER-RNA SYNTHETASE | CHEMICAL COMPLEMENTATION | COMPUTATIONAL DESIGN | ESCHERICHIA-COLI | MOLECULAR EVOLUTION | GENETICS & HEREDITY | ANTIBIOTIC-RESISTANCE | IN-VITRO COMPARTMENTALIZATION | YEAST SURFACE DISPLAY | Proteins - genetics | Animals | Proteins - metabolism | Protein Engineering - methods | Humans | Substrate Specificity | Directed Molecular Evolution | Genetic Techniques | Genetic research | Cellular proteins | Research | Properties | Genetic regulation
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8. Full Text Antibiotic tolerance facilitates the evolution of resistance
by Levin-Reisman, Irit and Ronin, Irine and Gefen, Orit and Braniss, Ilan and Shoresh, Noam and Balaban, Nathalie Q
Science, ISSN 0036-8075, 02/2017, Volume 355, Issue 6327, pp. 826 - 830
Controlled experimental evolution during antibiotic treatment can help to explain the processes leading to antibiotic resistance in bacteria. Recently,... 
PERSISTER CELLS | INSERTION | BETA-LACTAMASE | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | MUTATIONS | PROMOTER | EMERGENCE | Promoter Regions, Genetic | Escherichia coli - drug effects | Bacteria - drug effects | Bacterial Proteins - genetics | Drug Tolerance | Directed Molecular Evolution | Bacteria - genetics | beta-Lactamases - genetics | DNA Mutational Analysis | Escherichia coli - genetics | Ampicillin - pharmacology | Anti-Bacterial Agents - pharmacology | Mutation | Drug Resistance, Multiple, Bacterial - genetics | Evolution, Molecular | Observations | Drug resistance in microorganisms | Antibiotics | Antibiotic resistance | Antibiotic tolerance | Bacteria | Evolution | In vitro | Population genetics | Mutations | Populations | Emergence | Mathematical models | Tolerances
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9. Directed enzyme evolution
: screening and selection methods
by Arnold, Frances Hamilton and Georgiou, George and SpringerLink (Online service)
2003, Methods in molecular biology, ISBN 1592593968, Volume 230., xv, 383
Directed evolution, the application of evolutionary design to enzyme engineering, requires effective screening strategies to isolate those proteins that... 
Enzymes | Molecular evolution | Gene Library | methods | Protein Engineering | Directed Molecular Evolution | Genetic engineering | Laboratory manuals | Gene libraries | Evolution, Molecular | Biotechnology | Cytology | Cell Biology | Life Sciences
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10. Origin and evolution of telomeres
2008, ISBN 9781587063091, 176
Book
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11. Full Text Directed Evolution: Bringing New Chemistry to Life
by Arnold, Frances H
Angewandte Chemie International Edition, ISSN 1433-7851, 04/2018, Volume 57, Issue 16, pp. 4143 - 4148
Tailor‐made : Discussed herein is the ability to adapt biology's mechanisms for innovation and optimization to solving problems in chemistry and engineering.... 
enzymes | protein engineering | heme proteins | biocatalysis | synthetic methods | CARBENE | CYCLOPROPANATION | CHEMISTRY, MULTIDISCIPLINARY | C-H AMINATION | ENGINEERED CYTOCHROME-P450 ENZYMES | CATALYSTS | Cytochromes c - chemistry | Silanes - chemistry | Biocatalysis | High-Throughput Screening Assays | Cytochromes c - metabolism | Boranes - chemistry | Protein Engineering | Directed Molecular Evolution | Silanes - metabolism | Boranes - metabolism | Rhodothermus - enzymology | Proteins | Heme | Evolution | Biology | Directed evolution | Catalysts | Optimization | Innovations
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12. Full Text Hybrid Origins and Homoploid Reticulate Evolution within Heliosperma (Sileneae, Caryophyllaceae)—A Multigene Phylogenetic Approach with Relative Dating
by Božo Frajman and Frida Eggens and Bengt Oxelman and Teknisk-naturvetenskapliga vetenskapsområdet and Biologiska sektionen and Uppsala universitet and Systematisk botanik and Systematisk biologi and Institutionen för evolution, genomik och systematik
Systematic Biology, ISSN 1063-5157, 6/2009, Volume 58, Issue 3, pp. 328 - 345
We used four potentially unlinked nuclear DNA regions from the gene family encoding the second largest subunit of the RNA polymerases, as well as the psbE-petG... 
Datasets | Taxa | Chloroplasts | Genes | Phylogenetics | Evolution | Gene duplication | Phylogeny | Topology | Genetic hybridization | Incongruence | Lineage sorting | Relative dating | PATHd8 | RPB2 | RPA2 | RPD2 | R8s | BEAST | Homoploid hybridization | MOLECULAR EVOLUTION | LIKELIHOOD APPROACH | SPECIES TREES | CHLOROPLAST CAPTURE | r8s | DIVERGENCE TIMES | CONCERTED EVOLUTION | GENE TREES | EVOLUTIONARY BIOLOGY | ABSOLUTE RATES | TRIBE SILENEAE CARYOPHYLLACEAE | lineage sorting | incongruence | relative dating | homoploid hybridization | DUPLICATED GENES | DNA, Chloroplast - genetics | DNA-Directed RNA Polymerases - genetics | Caryophyllaceae - genetics | Hybridization, Genetic | Biological Sciences | Biology | Naturvetenskap | Biologiska vetenskaper | Biologi | Natural Sciences
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13. Full Text Biocatalysts by evolution
by Jäckel, Christian and Hilvert, Donald
Current Opinion in Biotechnology, ISSN 0958-1669, 2010, Volume 21, Issue 6, pp. 753 - 759
Proteins evolve by iterative cycles of mutation, selection and amplification. Analogous evolutionary strategies are being profitably exploited in the... 
Internal Medicine | ENZYME EVOLUTION | ENANTIOSELECTIVITY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | AMINO-ACIDS | COMPUTATIONAL DESIGN | BIOCHEMICAL RESEARCH METHODS | CONSENSUS | SATURATION MUTAGENESIS | PROTEIN DESIGN | GENETIC SELECTION | DIRECTED EVOLUTION | FAMILY | Proteins - genetics | Directed Molecular Evolution - methods | Biocatalysis | Proteins - metabolism | Proteins - chemistry | Mutagenesis | Discovery and exploration | Proteins | Outer space | Index Medicus
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