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Journal of clinical oncology, ISSN 1527-7755, 2014, Volume 32, Issue 13, pp. 1302 - 1308
Journal Article
Biomaterials, ISSN 0142-9612, 2016, Volume 101, pp. 131 - 142
Abstract Caspase-activated prodrug chemotherapy is introduced and demonstrated using the composite nanoparticles (NPs), which deliver doxorubicin (DOX) and... 
Advanced Basic Science | Dentistry | Heparin | Doxorubicin-induced apoptosis-targeted chemotherapy | Doxorubicin prodrug | Caspase-3 | Doxorubicin | The composite nanoparticles | MATERIALS SCIENCE, BIOMATERIALS | ACID | DRUG-DELIVERY | INDUCED APOPTOSIS | ENGINEERING, BIOMEDICAL | CARDIOTOXICITY | chemotherapy | CHILDREN | BREAST-CANCER | HETEROGENEITY | THERAPY | MOUSE MODEL | Doxorubicin-induced apoptosis-targeted | Neoplasms - metabolism | Prodrugs - administration & dosage | Doxorubicin - therapeutic use | Heparin - metabolism | Nanoparticles - analysis | Apoptosis - drug effects | Humans | Caspase 3 - metabolism | Heparin - administration & dosage | Heparin - therapeutic use | Male | Heparin - pharmacokinetics | Prodrugs - metabolism | Tissue Distribution | Nanoparticles - therapeutic use | Nanoparticles - metabolism | Doxorubicin - metabolism | Antibiotics, Antineoplastic - pharmacokinetics | Doxorubicin - administration & dosage | Rats, Sprague-Dawley | Doxorubicin - pharmacokinetics | Neoplasms - drug therapy | Antibiotics, Antineoplastic - administration & dosage | Animals | Antibiotics, Antineoplastic - therapeutic use | Prodrugs - pharmacokinetics | Cell Line, Tumor | Mice | Nanoparticles - administration & dosage | Prodrugs - therapeutic use | Antibiotics, Antineoplastic - metabolism | Nanoparticles | Chemotherapy | Anthracyclines | Measuring instruments | Imaging systems | High performance liquid chromatography | Cancer | Index Medicus | Drugs | Effectiveness | Activation | Chemical compounds | Apoptosis | Tumors
Journal Article
BMC cancer, ISSN 1471-2407, 2016, Volume 16, Issue 1, pp. 352 - 352
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 1, p. e82331
Brain cancer is a devastating disease affecting many people worldwide. Effective treatment with chemotherapeutics is limited due to the presence of the... 
MALIGNANT GLIOMA | CELLS | TRANSPORT | MULTIDISCIPLINARY SCIENCES | BARRIER | METASTASES | ADRIAMYCIN | BIODISTRIBUTION | MODEL | CHEMOTHERAPY | PACLITAXEL | Doxorubicin - blood | Glutathione - pharmacokinetics | Doxorubicin - therapeutic use | Capillaries - pathology | Humans | Brain Neoplasms - pathology | Body Weight - drug effects | Polyethylene Glycols - therapeutic use | Drug Delivery Systems | Brain - blood supply | Glutathione - pharmacology | Time Factors | Doxorubicin - analogs & derivatives | Female | Polyethylene Glycols - pharmacology | Glutathione - therapeutic use | Tissue Distribution - drug effects | Glutathione - analogs & derivatives | Endothelial Cells - metabolism | Polyethylene Glycols - pharmacokinetics | Treatment Outcome | Brain Neoplasms - drug therapy | Doxorubicin - pharmacokinetics | Brain - drug effects | Animals | Mice, Nude | Glioblastoma - pathology | Survival Analysis | Brain - pathology | Cell Proliferation - drug effects | Mice | Brain Neoplasms - ultrastructure | Endothelial Cells - pathology | Glioblastoma - drug therapy | Doxorubicin - pharmacology | Glutathione - blood | Drugs | Plasma physics | Drug delivery systems | Anthracyclines | Thiols | Gliomas | Brain tumors | Drug therapy | Cancer | Vehicles | Nuclear medicine | Bioluminescence | Neurosciences | Brain cancer | Glioblastoma | Drug delivery | Metastasis | Cancer therapies | Doxorubicin | Antioxidants | Blood-brain barrier | Inhibition | Xenobiotics | Glutathione | Medical treatment | Pharmacology | Breast cancer | Disease control | Endothelial cells | Studies | Chemotherapy | Brain research | Diffusion barriers | Medical prognosis | Pharmacokinetics | Tumors
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 11/2017, Volume 139, Issue 44, pp. 15940 - 15949
Journal Article
Journal Article
Biomaterials, ISSN 0142-9612, 2013, Volume 35, Issue 5, pp. 1643 - 1656
Journal Article
Journal Article
Journal Article
Journal of controlled release, ISSN 0168-3659, 10/2017, Volume 264, pp. 228 - 236
Journal Article