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Cancer Research, ISSN 0008-5472, 09/2013, Volume 73, Issue 17, pp. 5315 - 5319
Tumor graft models (also known as patient-derived xenografts or PDX) are based on the transfer of primary tumors directly from the patient into an... 
HETEROGENEITY | NUDE-MICE | METASTASIS | ONCOLOGY | GENE-EXPRESSION | DRUG RESPONSE | ESTABLISHMENT | IDENTIFICATION | CULTURE | LINES | CANCER STEM-CELLS | Xenograft Model Antitumor Assays | Animals | Humans | Mice | Cell Transformation, Neoplastic - pathology | Neoplasms - pathology | Disease Models, Animal | Precision Medicine
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 11/2019, p. 113729
Journal Article
Pigment Cell & Melanoma Research, ISSN 1755-1471, 04/2010, Volume 23, Issue 2, pp. 190 - 200
Summary BRAFV600E/K is a frequent mutationally active tumor‐specific kinase in melanomas that is currently targeted for therapy by the specific inhibitor... 
drug response | cell migration | ERK pathway | serum markers | melanoma | BRAF | RAF1 | Drug response | Melanoma | Serum markers | Cell migration | CANCER | CELL BIOLOGY | DERMATOLOGY | ONCOLOGY | KIT | RAF-1 | REVEALS | Original
Journal Article
Annals of Oncology, ISSN 0923-7534, 2017, Volume 28, Issue 10, pp. 2595 - 2605
Background: While patient-derived xenografts (PDXs) offer a powerful modality for translational cancer research, a precise evaluation of how accurately patient... 
Tumorgraft | Chemotherapy | Translational model | PDX | Patient-derived xenograft | PANCREATIC-CANCER | DRUG RESPONSE | chemotherapy | MOUSE MODELS | GEMCITABINE | translational model | TRIAL | BIOMARKERS | ONCOLOGY | patient-derived xenograft | COLORECTAL-CANCER | CARCINOMAS | UTILITY | tumorgraft | Original
Journal Article
Frontiers in Oncology, ISSN 2234-943X, 2012, Volume 2
The phosphoinositide 3-kinase (PI3K) pathway is frequently activated in cancer as a result of genetic (e.g. amplifications, mutations, deletions) and... 
Drug response | Genetic determinant | Cancer | PI3K pathway inhibitors | drug response | mTOR | genetic determinant
Journal Article
Drug Metabolism Reviews, ISSN 0360-2532, 10/2019, Volume 51, Issue 4, pp. 408 - 427
Diabetes is a major health problem worldwide. Glycemic control is the main goal in the management of type 2 diabetes. While many anti-diabetic drugs and... 
drug response | type 2 diabetes | Personalized diabetes therapy | omics-based therapy | drug metabolism
Journal Article
The Cochrane database of systematic reviews, ISSN 1469-493X, 2015, Volume 11, Issue 11, p. CD009885
Journal Article