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Developmental Biology, ISSN 0012-1606, 07/2019
During development, ribosome biogenesis and translation reach peak activities, due to impetuous cell proliferation. Current models predict that protein... 
Index Medicus
Journal Article
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 02/2010, Volume 17, Issue 2, pp. 360 - 372
  p27(BBP)/eIF6 (beta4-binding protein/eukaryotic initiation factor 6) regulates the joining of 40S and 60S ribosomal subunits, on receptor for activated C... 
Bcl-2/Bax | eIF6 | P27 | Xenopus laevis | Apoptosis
Journal Article
Journal of Medical Genetics, ISSN 0022-2593, 08/2017, Volume 54, Issue 8, pp. 558 - 566
Background For the final step of the maturation of the ribosome, the nascent 40S and 60S subunits are exported from the nucleus to the cell cytoplasm. To... 
YEAST | DIAGNOSIS | EIF6 RELEASE | GENETICS & HEREDITY | GUANINE-NUCLEOTIDE EXCHANGE | SYNDROME PROTEIN | SACCHAROMYCES-CEREVISIAE | GTPASE | RIBOSOME | SUBUNIT | Genetic aspects | Research | Gene mutations | Pancytopenia
Journal Article
ISSN 2212-4926, 2018
Mutations that target the ubiquitous process of ribosome assembly paradoxically cause diverse tissue-specific disorders (ribosomopathies) that are often... 
SBDS | ribosome | Shwachman-Diamond syndrome | eIF6 | DNAJC21 | myelodysplastic syndromes
Journal Article
by Lin, JX and Yu, XH and Xie, LP and Wang, PN and Li, TY and Xiao, YL and Zhou, JM and Peng, SY and Huang, J and Luo, YX and Huang, MJ and Wang, JP
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, ISSN 1550-7033, 07/2019, Volume 15, Issue 7, pp. 1556 - 1567
Journal Article
JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 06/2019, Volume 132, Issue 12, p. jcs228908
Receptor of activated protein C kinase 1 (RACK1) is a highly conserved eukaryotic protein that regulates several aspects of mRNA translation; yet, how it does... 
Translation | ACTIVATED C KINASE | CODON | Ribosome | RNA | INITIATION | RIBOSOME-ASSOCIATED PROTEIN | RECEPTOR | QUALITY-CONTROL | CELL BIOLOGY | YEAST | EIF6 | RACK1 | Evolution | SCAFFOLD PROTEIN | ZNF598
Journal Article
European Journal of Cancer, ISSN 0959-8049, 09/2018, Volume 101, pp. 165 - 180
Non–small cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide. Dysregulation of protein synthesis plays a major role in... 
Adenocarcinoma | Non–small cell lung cancer | Squamous cell carcinoma | Eukaryotic translation initiation factor 6 | PROTEIN | TUMOR | P27(BBP) | EIF6 RELEASE | BIOGENESIS | ONCOLOGY | Non-small cell lung cancer | IN-VIVO | GROWTH | EXPRESSION | 60S RIBOSOMAL-SUBUNIT | 80S RIBOSOME | Immunohistochemistry | Adenocarcinoma - pathology | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Lung Neoplasms - metabolism | Cell Survival - genetics | Lung Neoplasms - pathology | Male | Adenocarcinoma - metabolism | RNA Interference | Female | Adenocarcinoma - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Eukaryotic Initiation Factors - genetics | Lung Neoplasms - genetics | A549 Cells | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Kaplan-Meier Estimate | Eukaryotic Initiation Factors - biosynthesis | Disease Progression | Cell Line, Tumor | Aged | Proteins | RNA | Lung cancer, Small cell | Development and progression | Protein biosynthesis | Lung cancer, Non-small cell | Genetic translation | Cell proliferation | Lung cancer | mRNA | Cancer therapies | Carcinogenesis | Initiation factors | Eukaryotes | Cell growth | Carcinogens | RNA processing | Translation | Translation initiation factor eIF6 | Cell survival | Small cell lung carcinoma | rRNA | Translation initiation | Lung carcinoma | Tumor cell lines | Protein synthesis | Cell lines | Cancer | Apoptosis | Index Medicus
Journal Article
Cell Metabolism, ISSN 1550-4131, 12/2018, Volume 28, Issue 6, pp. 895 - 906.e5
Naive T cells respond to T cell receptor (TCR) activation by leaving quiescence, remodeling metabolism, initiating expansion, and differentiating toward... 
GLUT1 | eIF4E | transcriptome | CD4+ T cell | metabolism | translational control | eIF6 | metabolome | ACC1 | proteome | CD4 | T cell | EFFECTOR | TRANSCRIPTS | HOMEOSTASIS | FATTY-ACID SYNTHESIS | HUMAN NAIVE | INITIATION | GROWTH | ENDOCRINOLOGY & METABOLISM | PROLIFERATION | REGULATORY T | DIFFERENTIATION | CELL BIOLOGY
Journal Article
Developmental Biology, ISSN 0012-1606, 07/2017, Volume 427, Issue 1, pp. 148 - 154
Journal Article
Cell Reports, ISSN 2211-1247, 11/2017, Volume 21, Issue 6, pp. 1507 - 1520
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 12/2018, Volume 38, Issue 23
The translational capability of ribosomes deprived of specific nonfundamental ribosomal proteins may be altered. Physiological mechanisms are scanty, and it is... 
EIF6 | Ribosomes | RACK1 | PKC | mRNA | EIF4E | Translational control | Cell signaling | Stress | Puromycin | stress | CELLS | eIF4E | MESSENGER-RNA TRANSLATION | PROTEIN-KINASE-C | BIOCHEMISTRY & MOLECULAR BIOLOGY | CRYO-EM | HOMOLOG | translational control | CELL BIOLOGY | ribosomes | cell signaling | IN-VIVO | GROWTH | puromycin | eIF6 | PROGRESSION | 80S RIBOSOME | SUBUNIT
Journal Article
Genes and Development, ISSN 0890-9369, 2011, Volume 25, Issue 9, pp. 917 - 929
Journal Article
Journal Article