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European Journal of Immunology, ISSN 0014-2980, 2019, Volume 49, Issue 4, pp. 600 - 610
Efferocytosis is essential for homeostasis and prevention of the inflammatory and autoimmune diseases resulting from apoptotic cell lysis. CD93 is a... 
Efferocytosis | CD93 | Opsonin | Phagocytosis | Integrins
Journal Article
Current Opinion in Immunology, ISSN 0952-7915, 12/2018, Volume 55, pp. 54 - 61
LC3-associated phagocytosis (LAP) exists at the crossroads of the two evolutionary pathways of phagocytosis and autophagy. When a phagocyte engulfs an... 
NONCANONICAL AUTOPHAGY | NADPH OXIDASE | CLEARANCE | RUBICON | EFFEROCYTOSIS | SECRETION | IMMUNOLOGY | Immunotherapy
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 2/2017, Volume 37, Issue 2, pp. 183 - 189
Atherosclerosis is initiated by the subendothelial accumulation of apolipoprotein B-containing lipoproteins (apoB LPs), which initiates a sterile inflammatory... 
atherosclerosis | macrophages | necrosis | inflammation resolution | efferocytosis
Journal Article
Nature Communications, ISSN 2041-1723, 09/2016, Volume 7, Issue 1, p. 12859
Chronic unresolved inflammation plays a causal role in the development of advanced atherosclerosis, but the mechanisms that prevent resolution in... 
NUCLEAR-LOCALIZATION | LIPOXIN A | A HYDROLASE | OXIDATIVE STRESS | ANTIINFLAMMATORY ACTIVITY | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | RESOLUTION | EFFEROCYTOSIS | 5-LIPOXYGENASE | HUMAN PHAGOCYTES
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2011, Volume 2
A critical function of macrophages within the inflammatory milieu is the removal of dying cells by a specialized phagocytic process called efferocytosis (to... 
Efferocytosis | Inflammation | Alternative activation | Apoptotic cell | Classical activation | Macrophage | macrophage | apoptotic cell | classical activation
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2014, Volume 5
Complement is a critical system of enzymes, regulatory proteins and receptors that regulates both innate and adaptive immune responses. Natural mutations in... 
C1q | Cytokine | Efferocytosis | Complement | Inflammasome | Phagocytosis | Adiponectin | Macrophage | cytokine | macrophage
Journal Article
Circulation Research, ISSN 0009-7330, 02/2017, Volume 120, Issue 4, pp. 624 - 626
Journal Article
European Journal of Immunology, ISSN 0014-2980, 9/2011, Volume 41, Issue 9, pp. 2515 - 2518
Accumulating evidence supports the notion that defective phagocytic clearance of dying cells, or defective “efferocytosis,” is causally linked to the... 
Efferocytosis | Macrophage
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 09/2018, Volume 115, Issue 36, pp. E8469 - E8478
Inflammatory responses are terminated by the clearance of dead cells, a process termed efferocytosis. A consequence of efferocytosis is the synthesis of the... 
DC EFFEROCYTOSIS | IFN-GAMMA | MULTIDISCIPLINARY SCIENCES | efferocytosis | EP4 | INNATE | prostaglandin E-2 | CYCLIC-AMP | IL-17-PRODUCING T-CELLS | STAPHYLOCOCCUS-AUREUS | DIFFERENTIATION | infected apoptotic cells | CITROBACTER-RODENTIUM | Th17 cells | CROSS-PRESENTATION
Journal Article
Circulation Research, ISSN 0009-7330, 02/2017, Volume 120, Issue 4, pp. 624 - 626
Many studies have noted similarities between atherosclerosis and cancer including pronounced cellular plasticity, clonal expansion of cellular subtypes,... 
atherosclerosis | macrophages | efferocytosis | smooth muscle | oncogenes | neoplasms | myocytes
Journal Article
Circulation Journal, ISSN 1346-9843, 2016
Macrophage apoptosis and the ability of macrophages to clean up dead cells, a process called efferocytosis, are crucial determinants of atherosclerosis lesion... 
SR-BI | Atherosclerosis | Efferocytosis | Macrophages | Apoptosis
Journal Article
Cell Stem Cell, ISSN 1934-5909, 06/2018, Volume 22, Issue 6, pp. 824 - 833
Mesenchymal stromal cells (MSCs) have been the subject of clinical trials for more than a generation, and the outcomes of advanced clinical trials have fallen... 
thawing | FDA | immune compatibility | biomarkers | mesenchymal stromal cells | efferocytosis | clinical trials | graft versus host disease | Crohn’s disease | Crohn's disease | PROGENITOR CELLS | TRIAL | TROPHOBLAST | STEM-CELLS | STEROID-RESISTANT | SAFETY | MACROPHAGES | PERIANAL FISTULAS | DOUBLE-BLIND | VERSUS-HOST-DISEASE | CELL & TISSUE ENGINEERING | CELL BIOLOGY
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 05/2019, Volume 79, Issue 10, pp. 2669 - 2683
Tyro3, Axl, and Mertk (TAM) represent a family of homologous tyrosine kinase receptors known for their functional role in phosphatidylserine (PS)-dependent... 
MERTK INHIBITION | SIGNALING PATHWAYS | ONCOLOGY | GROWTH | EFFEROCYTOSIS | PROTEIN-S | PHOSPHATIDYLSERINE | EXPRESSION | SMALL-MOLECULE INHIBITION | AXL KINASE | FAMILY
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 12/2017, Volume 27, Issue 17, pp. 1412 - 1431
Aims: 15-Deoxy-Δ 12,14 -prostaglandin J 2 (15d-PGJ 2 ) has been shown to rescue cells from inflammatory insults and to participate in the resolution of acute... 
Original Research Communications | prostaglandin J | 15-Deoxy-Δ | heme oxygenase-1 | Nrf2 | resolution of inflammation | efferocytosis | Index Medicus
Journal Article
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 10/2018, Volume 9
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2012, Volume 3, p. 4
Monocytes that migrate into tissues during inflammatory episodes and differentiate to macrophages were previously classified as classically (M1) or... 
Efferocytosis | Pro-resolving lipid mediators | Macrophage differentiation | Resolution of inflammation | IMMUNOLOGY | macrophage differentiation | pro-resolving lipid mediators | resolution of inflammation | efferocytosis
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 11/2017, Volume 8, p. 1428
Phagocytic sensing and engulfment of dying cells and extracellular bodies initiate an intracellular signaling cascade within the phagocyte that can polarize... 
Heart | Efferocytosis | Cardiomyocyte | Phagocytosis | Macrophage | phagocytosis | macrophage | heart | efferocytosis | cardiomyocyte
Journal Article