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Journal of Alzheimer's disease : JAD, ISSN 1387-2877, 2019, Volume 67, Issue 1, pp. 393 - 410
Cholesterol dyshomeostasis has been linked to the pathogenesis of sporadic Alzheimer’s disease (AD). In furthering the understanding of mechanisms by which... 
BACE1 | TRPML1 | LDL | cholesterol | ML-SA1 | neurons | amyloid beta | endolysosome pH
Journal Article
Cancer Reports, ISSN 2573-8348, 12/2019, Volume 2, Issue 6, p. n/a
Background Glioblastoma multiforme (GBM) is a very aggressive form of brain cancer that carries with it a tragically poor prognosis. As with many other forms... 
Cytosolic pH | Endolysosome pH | Extracellular pH | Endolysosomes | Glioblastoma | v‐ATPase
Journal Article
Cancer Reports, ISSN 2573-8348, 12/2019, Volume 2, Issue 6, p. n/a
Background Glioblastoma multiforme (GBM) is a Grade IV astrocytoma with an aggressive disease course and a uniformly poor prognosis. Pathologically, GBM is... 
glioblastoma multiforme (GBM) | lysosome destabilizing drugs | pH | endolysosomes | vacuolar ATPase
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 2019, Volume 67, Issue 1, pp. 393 - 410
Journal Article
Journal Article
BMC Cell Biology, ISSN 1471-2121, 08/2013, Volume 14, Issue 1, pp. 35 - 35
Background: Endolysosomes play a key role in maintaining the homeostasis of the cell. They are made of a complex set of proteins that degrade lipids, proteins... 
Primary cells | T cell epitope production | Endolysosome | Protein degradation | HIV | Proteases | Antigen processing | Cathepsins | MHC | Mass spectrometry | LYSOSOMAL STORAGE DISORDER | IMMUNE ESCAPE | CATHEPSIN-S | DEFICIENCY | CELL BIOLOGY | MHC CLASS-I | EPITOPE PRESENTATION | DISEASE | INHIBITORS | EXPRESSION | Enzymes | Peptides | Proteolysis | Lipids | T cells | Antigenic determinants | Proteins | Studies | Acids | Disease
Journal Article
Biochemical Journal, ISSN 0264-6021, 11/2011, Volume 439, Issue 3, pp. 349 - 374
Journal Article
ELIFE, ISSN 2050-084X, 12/2019, Volume 8
Mammalian two-pore-channels (TPC1, 2; TPCN1, TPCN2) are ubiquitously- expressed, P1(3,5)P-2-activated, Na+-selective channels in the endosomes and lysosomes... 
NAADP | MECHANISM | TPC | CALCIUM | BIOLOGY | TRAFFICKING | DISORDERS | TARGETS | ION CHANNELS | PROTEINS | SELECTIVITY FILTER | Sodium channels | Laboratories | Channel gating | High-throughput screening | Electrophysiology | Homeostasis | Lysosomes | Permeability | Autophagy | Sodium channels (voltage-gated) | Agonists | Membrane trafficking | Libraries | Gating | Phagocytosis | Endosomes
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 09/2014, Volume 307, Issue 5, pp. L355 - L363
Klebsiella pneumoniae (Kp) is a Gram-negative bacterium that can cause serious infections in humans. Autophagy-related gene 7 (Atg7) has been implicated in... 
Knockout mice | Reactive oxygen species | Alveolar macrophage | Autophagy | Autophagy-related gene 7 | Gram-negative bacterial infection | Lung injury | alveolar macrophage | PHYSIOLOGY | autophagy | knockout mice | PROTEIN | LOWER RESPIRATORY-TRACT | autophagy-related gene 7 | lung injury | PSEUDOMONAS-AERUGINOSA INFECTION | TAT-INDUCED NEUROTOXICITY | ENDOLYSOSOME INVOLVEMENT | RESPIRATORY SYSTEM | LUNG EPITHELIAL-CELLS | reactive oxygen species | DISEASE | ALVEOLAR MACROPHAGES | NF-KAPPA-B | Klebsiella Infections - metabolism | Male | Pneumonia, Bacterial - metabolism | Pneumonia - mortality | Pneumonia, Bacterial - mortality | Inflammation Mediators - metabolism | Pneumonia - immunology | Female | Fluorescent Antibody Technique, Indirect | Macrophages, Alveolar - immunology | Macrophages, Alveolar - microbiology | Pneumonia, Bacterial - microbiology | Cytokines - metabolism | Enzyme-Linked Immunosorbent Assay | Mice, Inbred C57BL | Cells, Cultured | Survival Rate | Pneumonia - microbiology | Klebsiella Infections - microbiology | Blotting, Western | Mice, Knockout | Microtubule-Associated Proteins - physiology | Autophagy-Related Protein 7 | Animals | Klebsiella Infections - immunology | Klebsiella pneumoniae - pathogenicity | Klebsiella Infections - mortality | Pneumonia, Bacterial - immunology | Mice | Macrophages, Alveolar - metabolism | Lipid Peroxidation | Pneumonia - metabolism | Call for Papers
Journal Article
BRAIN RESEARCH, ISSN 0006-8993, 11/2019, Volume 1722, p. 146389
Endolysosomes, mitochondria, peroxisomes, endoplasmic reticulum, and plasma membranes are now known to physically and functionally interact with each other.... 
Inter-organellar signaling | CHRONIC-EXPOSURE | Calcium | TAT NEUROTOXICITY | NITRIC-OXIDE SYNTHASE | INTRACELLULAR CALCIUM | HIV-1 associated neurocognitive disorder | ACIDIC ORGANELLES | NEUROSCIENCES | Mitochondria | EMERGING ROLE | AMYLOID-BETA | CALCIUM-RELEASE | LYSOSOMAL CALCIUM | ENDOPLASMIC-RETICULUM | Endolysosomes | Endoplasmic reticulum | Alzheimer's disease
Journal Article
Immunology and Cell Biology, ISSN 0818-9641, 03/2009, Volume 87, Issue 3, pp. 209 - 217
Journal Article