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Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 31, pp. 12054 - 12067
Nidovirus endoribonucleases (NendoUs) include nonstructural protein 15 (nsp15) from coronaviruses and nsp11 from arteriviruses, both of which have been... 
PROTEIN | protein evolution | MOUSE HEPATITIS-VIRUS | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | protein purification | viral protein | evolution | REPLICATIVE ENDORIBONUCLEASE | INDUCTION | DISCOVERY | MURINE | endoribonuclease | XENDOU | oligomerization | PDCoV nsp15 | nidovirus | CORONAVIRUS ENDORIBONUCLEASE | Endoribonucleases - chemistry | Coronavirus - classification | Endoribonucleases - genetics | Virus Replication - genetics | Protein Multimerization | Nidovirales - genetics | Crystallography, X-Ray | SARS Virus - metabolism | Protein Subunits - metabolism | SARS Virus - classification | Nidovirales - chemistry | Viral Nonstructural Proteins - chemistry | SARS Virus - genetics | Coronavirus - metabolism | Arterivirus - metabolism | Cloning, Molecular | Escherichia coli - metabolism | Arterivirus - chemistry | Protein Interaction Domains and Motifs | Arterivirus - classification | Binding Sites | Protein Subunits - genetics | Recombinant Proteins - metabolism | Amino Acid Sequence | Protein Conformation, alpha-Helical | Gene Expression | Endoribonucleases - metabolism | Genetic Vectors - chemistry | Genetic Vectors - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Viral Nonstructural Proteins - genetics | Recombinant Proteins - genetics | SARS Virus - chemistry | Arterivirus - genetics | Sequence Homology, Amino Acid | Nidovirales - classification | Sequence Alignment | Coronavirus - chemistry | Protein Conformation, beta-Strand | Escherichia coli - genetics | Coronavirus - genetics | Protein Binding | Viral Nonstructural Proteins - metabolism | Nidovirales - metabolism | Protein Subunits - chemistry | Evolution, Molecular | Microbiology
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2017, Volume 114, Issue 21, pp. E4251 - E4260
Journal Article
Blood, ISSN 0006-4971, 04/2017, Volume 129, Issue 17, pp. 2420 - 2428
The endoplasmic reticulum kinase inositol-requiring enzyme 1 (IRE1) and its downstream target X-box-binding protein 1 (XBP1) drive B-cell differentiation... 
GERMINAL CENTER FORMATION | MULTIPLE-MYELOMA | B-CELL LYMPHOMA | UNFOLDED-PROTEIN RESPONSE | TRANSCRIPTION FACTOR XBP-1 | CERVICAL-CANCER | ENDOPLASMIC-RETICULUM STRESS | BIVALENT PROMOTERS | DIFFERENTIATION | HEMATOLOGY | METHYLTRANSFERASE EZH2 | Enhancer of Zeste Homolog 2 Protein - antagonists & inhibitors | RNA, Messenger - immunology | Endoribonucleases - genetics | Cell Proliferation | Epigenesis, Genetic | Germinal Center - immunology | Humans | Gene Expression Regulation, Neoplastic | X-Box Binding Protein 1 - antagonists & inhibitors | Endoribonucleases - antagonists & inhibitors | Mice, 129 Strain | Plasma Cells - pathology | Lymphoma, Large B-Cell, Diffuse - therapy | RNA, Messenger - antagonists & inhibitors | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Lymphoma, Large B-Cell, Diffuse - immunology | Cell Differentiation | B-Lymphocytes - pathology | Promoter Regions, Genetic | Enhancer of Zeste Homolog 2 Protein - genetics | X-Box Binding Protein 1 - immunology | Histones - immunology | Lymphoma, Large B-Cell, Diffuse - pathology | Signal Transduction | RNA, Messenger - genetics | Protein-Serine-Threonine Kinases - genetics | Germinal Center - pathology | Indazoles - pharmacology | Xenograft Model Antitumor Assays | Leupeptins - pharmacology | Animals | B-Lymphocytes - immunology | Histones - genetics | Enhancer of Zeste Homolog 2 Protein - immunology | Cell Line, Tumor | Protein-Serine-Threonine Kinases - immunology | Mice | Lymphoma, Large B-Cell, Diffuse - genetics | X-Box Binding Protein 1 - genetics | Pyridones - pharmacology | Endoribonucleases - immunology | Plasma Cells - immunology
Journal Article
Cell, ISSN 0092-8674, 07/2014, Volume 158, Issue 3, pp. 534 - 548
Journal Article
Science, ISSN 0036-8075, 11/2012, Volume 338, Issue 6108, pp. 818 - 822
Journal Article
Nature, ISSN 0028-0836, 12/2008, Volume 456, Issue 7224, pp. 993 - 996
The exosome is a major eukaryotic nuclease located in both the nucleus and the cytoplasm that contributes to the processing, quality control and/ or turnover... 
COMPLEX | MESSENGER-RNA | YEAST EXOSOME | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | DEGRADATION | POLY(A) POLYMERASE | QUALITY-CONTROL