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Journal of Lipid Research, ISSN 0022-2275, 04/2011, Volume 52, Issue 4, pp. 826 - 832
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, pp. e0134437 - e0134437
Journal Article
Journal Article
Lipids, ISSN 0024-4201, 8/2013, Volume 48, Issue 8, pp. 769 - 778
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 47, pp. 19198 - 19208
Tumors depend on their microenvironment for sustained growth, invasion, and metastasis. In this environment, endothelial cells (ECs) are an important stromal... 
lysosomal acid lipase | ACTIVATION | ANGIOGENESIS | endothelial cell | BIOCHEMISTRY & MOLECULAR BIOLOGY | MTOR PATHWAY | CANCER-CELL PROLIFERATION | cancer therapy | Rab7 GTPase | METABOLISM | DISEASE | tumor metastasis | tumor microenvironment | SUPPRESSOR-CELLS | LAL(-/-) MICE | lysosome | PROMOTES | PROGRESSION | Index Medicus | Metabolism
Journal Article
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 06/2014, Volume 1841, Issue 6, pp. 906 - 917
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 12/2018, Volume 9, Issue 12, pp. 1263 - 1268
Endothelial lipase (EL) selectively metabolizes high density lipoprotein (HDL) particles. Inhibition of EL has been shown to increase HDL concentration in... 
atherosclerosis | Endothelial lipase | HDL | LIPOPROTEIN METABOLISM | CHEMISTRY, MEDICINAL | HEPATIC LIPASE | HDL CHOLESTEROL LEVELS
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 12/2018, Volume 28, Issue 23-24, pp. 3721 - 3725
Endothelial lipase (EL) inhibitors have been shown to elevate HDL-C levels in pre-clinical murine models and have potential benefit in prevention and treatment... 
Tetrahydropyrimidinedione (THP) | Endothelial lipase (EL) inhibitors | High density lipoprotein cholesterol (HDL-C) | Atherosclerosis | POT ASYMMETRIC-SYNTHESIS | CHEMISTRY, MEDICINAL | ACIDS | CHEMISTRY, ORGANIC | IMPACT | METABOLISM | REDUCTION | BUTANESULFINYL-PROTECTED AMINES | HDL CHOLESTEROL | Lipase | Analysis | Endothelium
Journal Article