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Journal Article
Nature Medicine, ISSN 1078-8956, 03/2010, Volume 16, Issue 3, pp. 279 - 285
Control of blood vessel tone is central to vascular homeostasis. Here we show that metabolism of tryptophan to kynurenine by indoleamine 2,3-dioxygenase (Ido)... 
MEDICINE, RESEARCH & EXPERIMENTAL | TRYPTOPHAN-METABOLISM | NITRIC-OXIDE SYNTHASE | MURINE CEREBRAL MALARIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDOLEAMINE 2,3-DIOXYGENASE EXPRESSION | HEME OXYGENASE-1-DEFICIENT MICE | BLOOD-PRESSURE | CELL BIOLOGY | STIMULATED PHOSPHOPROTEIN VASP | SOLUBLE GUANYLYL CYCLASE | L-ARGININE | ENDOTOXIC-SHOCK | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Coronary Vessels - physiopathology | Kynurenine - biosynthesis | Endothelium, Vascular - enzymology | Kynurenine - physiology | Endothelium, Vascular - physiology | Dose-Response Relationship, Drug | Plasmodium berghei | Tryptophan - blood | Endotoxemia - physiopathology | Guanylate Cyclase - physiology | Blood Pressure - drug effects | Blood Pressure - physiology | Muscle, Smooth, Vascular - physiology | Muscle, Smooth, Vascular - drug effects | Rats, Inbred SHR | Coronary Vessels - drug effects | Endothelium-Dependent Relaxing Factors - physiology | Kynurenine - pharmacology | Mice, Inbred C57BL | Endothelium, Vascular - physiopathology | Interferon-gamma - physiology | Rats | Guanylate Cyclase - metabolism | Adenylyl Cyclases - metabolism | Animals | Tryptophan - physiology | Malaria - physiopathology | Mice | Tryptophan - pharmacology | Enzyme Activation - physiology | Indoleamine-Pyrrole 2,3,-Dioxygenase - antagonists & inhibitors | Indoleamine-Pyrrole 2,3,-Dioxygenase - physiology | Inflammation - physiopathology | Amino acids | Inflammation | Research | Endothelium-derived relaxing factors | Health aspects | Endothelium | Neurotransmitters | Blood pressure | Metabolism | Rodents | Inflammatory diseases | Index Medicus
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 03/2013, Volume 33, Issue 3, pp. 629 - 636
OBJECTIVE—Adenosine dilates human coronary arteries by activating potassium channels in an endothelial cell-independent manner. Cell surface... 
adenosine | vasodilation | endothelium-derived relaxant factor | HUMAN CORONARY ARTERIOLES | CA2+-ACTIVATED K+ CHANNELS | BLOOD-FLOW | HYPOXIA | ADENOSINE-TRIPHOSPHATE | FLOW-INDUCED DILATION | PERIPHERAL VASCULAR DISEASE | HYDROGEN-PEROXIDE | RAT-HEART | ATP RELEASE | HEMATOLOGY | 5'-Nucleotidase - antagonists & inhibitors | 5'-Nucleotidase - genetics | Muscle, Smooth, Vascular - metabolism | Adenine Nucleotides - pharmacology | Adenosine Deaminase - metabolism | Humans | Male | Microscopy, Video | 5'-Nucleotidase - deficiency | Purinergic P1 Receptor Antagonists - pharmacology | Dose-Response Relationship, Drug | Spectrometry, Mass, Electrospray Ionization | GPI-Linked Proteins - deficiency | Vasodilator Agents - metabolism | Chromatography, Liquid | Female | Biological Factors - metabolism | GPI-Linked Proteins - antagonists & inhibitors | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Muscle, Smooth, Vascular - drug effects | Coronary Vessels - drug effects | Coronary Vessels - enzymology | Vasodilator Agents - pharmacology | Enzyme Inhibitors - pharmacology | GPI-Linked Proteins - metabolism | Inosine Nucleotides - pharmacology | Mice, Knockout | Animals | Membrane Potentials | Adenine Nucleotides - metabolism | Adenosine - metabolism | Mice | Vasodilation - drug effects | 5'-Nucleotidase - metabolism | Endothelial Cells - enzymology | Endothelial Cells - drug effects | GPI-Linked Proteins - genetics | Index Medicus
Journal Article
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 04/2007, Volume 115, Issue 13, pp. 1789 - 1797
Background-Preeclampsia is characterized clinically by hypertension and proteinuria. Soluble Flt-1 (sFlt-1; also known as soluble vascular endothelial growth... 
Pregnancy | Angiogenesis | Endothelium-derived factors | Preeclampsia | Heme oxygenase-1 | Statins | Endothelium | VITAMIN-C | endothelium | PREGNANCY-INDUCED HYPERTENSION | CARDIAC & CARDIOVASCULAR SYSTEMS | HUMAN PLACENTA | angiogenesis | pregnancy | TISSUE-DAMAGE | heme oxygenase-1 | preeclampsia | MEDIATED ANGIOGENESIS | endothelium-derived factors | TYROSINE KINASE-1 | CYTOKINE PRODUCTION | CARBON-MONOXIDE | statins | PERIPHERAL VASCULAR DISEASE | ISCHEMIA-REPERFUSION | ENDOTHELIAL GROWTH-FACTOR | Endothelium, Vascular - cytology | Oxidative Stress | Humans | Recombinant Fusion Proteins - physiology | Vascular Endothelial Growth Factor Receptor-1 - physiology | Heme Oxygenase-1 - deficiency | Pregnancy Proteins - pharmacology | Cell Hypoxia | Endoglin | Carbon Monoxide - pharmacology | Swine | Heme Oxygenase-1 - physiology | Female | Pre-Eclampsia - metabolism | Receptors, Cell Surface - physiology | Vascular Endothelial Growth Factor Receptor-2 - physiology | Culture Media, Serum-Free - pharmacology | Heme Oxygenase (Decyclizing) - genetics | Vascular Endothelial Growth Factor A - pharmacology | Organ Culture Techniques | Cells, Cultured - drug effects | Heme Oxygenase (Decyclizing) - physiology | Endothelial Cells - metabolism | RNA, Small Interfering - pharmacology | Solubility | Rats | Antioxidants - pharmacology | Pre-Eclampsia - pathology | Mice, Knockout | Tumor Necrosis Factor-alpha - pharmacology | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Placenta - pathology | Placenta Growth Factor | Antigens, CD - physiology | Mice | Genetic Vectors | Interferon-gamma - pharmacology | Organometallic Compounds - pharmacology | Endothelial Cells - drug effects | Oxidases | Care and treatment | Physiological aspects | Diagnosis | Research | Vascular endothelial growth factor | Index Medicus | Abridged Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/1999, Volume 96, Issue 15, pp. 8663 - 8668
Journal Article
Circulation, ISSN 0009-7322, 1997, Volume 95, Issue 4, pp. 1030 - 1037
Background Vascular endothelial growth factor (VEGF)/ vascular permeability factor (VPF) is an endothelial cell (EC) mitogen. This feature is considered... 
endothelium-derived factors | endothelium | nitric oxide | CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | ANGIOGENESIS | RELAXING FACTOR | CAROTID-ARTERY | MECHANISMS | MITOGEN | SYNTHASE | BASAL RELEASE | PERIPHERAL VASCULAR DISEASE | VEGF RECEPTORS | EXPRESSION | Index Medicus | Abridged Index Medicus
Journal Article
Circulation, ISSN 0009-7322, 03/2001, Volume 103, Issue 12, pp. 1702 - 1708
Journal Article
Circulation, ISSN 0009-7322, 03/2004, Volume 109, Issue 11, pp. 1343 - 1348
Journal Article