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Brain Research, ISSN 0006-8993, 2011, Volume 1435, pp. 154 - 166
Abstract Mutations in the KCNA1 gene, which encodes for the α subunit of the voltage-gated potassium channel Kv1.1, cause episodic ataxia type 1 (EA1). EA1 is... 
Neurology | Animal model | Dominant-negative effect | Voltage-gated potassium channel shaker-related subfamily member 1 (Kcna1) | Episodic ataxia type 1 (EA1) | Voltage-sensor domain S4 | Phenotype-driven ENU mutagenesis | KV1.1 | MOUSE | POTASSIUM CHANNEL GENE | NEUROSCIENCES | FAST INACTIVATION | MICE LACKING | KCNA1 GENE | EPISODIC ATAXIA TYPE-1 | MISSENSE MUTATION | DYSFUNCTION | EXPRESSION | Xenopus | Electric Stimulation | Humans | Rats, Inbred F344 | Isaacs Syndrome - chemically induced | Body Weight - drug effects | Male | Mutagenesis - drug effects | Myokymia - mortality | Time Factors | DNA Mutational Analysis | Biophysical Phenomena - genetics | Swimming | Disease Models, Animal | Kv1.1 Potassium Channel - genetics | Membrane Potentials - drug effects | Gene Transfer Techniques | Isaacs Syndrome - genetics | Kv1.1 Potassium Channel - drug effects | Models, Molecular | Rats | Chromosome Mapping | Protein Transport - genetics | Patch-Clamp Techniques | Survival Analysis | Epilepsy - drug therapy | Mice | Membrane Potentials - genetics | Mutagens - toxicity | Ethylnitrosourea - toxicity | Electroencephalography | Epilepsy - mortality | Psychomotor Performance - physiology | Mutation, Missense - genetics | Oocytes | Rats, Mutant Strains | Antiemetics - therapeutic use | Threonine - genetics | Mutation, Missense - drug effects | Epilepsy - genetics | Electromyography | Isaacs Syndrome - mortality | Myokymia - genetics | Biotinylation | Cells, Cultured | Carbamazepine - therapeutic use | Serine - genetics | Myokymia - chemically induced | Animals | Epilepsy - chemically induced | Sequence Analysis | Animal genetic engineering | Epilepsy | Seizures (Medicine) | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2018, Volume 13, Issue 11, p. e0207747
Journal Article
Journal Article
Journal of Bioenergetics and Biomembranes, ISSN 0145-479X, 12/2003, Volume 35, Issue 6, pp. 671 - 685
Journal Article
MOLECULAR PHARMACOLOGY, ISSN 0026-895X, 10/2005, Volume 68, Issue 4, pp. 995 - 1005
Kv beta subunits are accessory proteins that modify gating of Kv1 channels. Kv beta 1.3 subunits bind to the N termini of Kv1.5 alpha-subunits and induce fast... 
ALPHA-SUBUNITS | SITE | HKV1.5 CHANNELS | GATED K+ CHANNELS | DETERMINANTS | EPISODIC ATAXIA TYPE-1 | BLOCK | PHARMACOLOGY & PHARMACY | DEPENDENT POTASSIUM CHANNELS | BETA-SUBUNIT | MOLECULAR-BASIS
Journal Article
Journal Article