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Cell (Cambridge), ISSN 0092-8674, 2017, Volume 171, Issue 4, pp. 877 - 889.e17
N6-methyladenosine (m6A), installed by the Mettl3/Mettl14 methyltransferase complex, is the most prevalent internal mRNA modification. Whether m6A regulates... 
Mettl14 | epitranscriptomics | human organoid | transcriptional prepatterning | neurogenesis | m6A | radial glia cell | schizophrenia | RNA methylation | autism
Journal Article
eLife, ISSN 2050-084X, 2016, Volume 5, Issue September
Methylation of adenosines at the N6 position (m6A) is a dynamic and abundant epitranscriptomic mark that regulates critical aspects of eukaryotic RNA... 
Post-transcription | Gene regulation | Genomes | Ribonucleic acid--RNA | Proteins | Enzymatic activity | Mutagenesis | Data collection | Catalysis | Sulfur | Methylation | Localization | Crystal structure
Journal Article
RNA, ISSN 1355-8382, 05/2017, Volume 23, Issue 5, pp. 611 - 618
RNA modifications are ubiquitous in biology, with over 100 distinct modifications. While the vast majority were identified and characterized on abundant... 
methyladenosine | Pseudouridine | Epitranscriptomics | RNA-protein interactions | PUMILIO | RNA binding proteins | Report | RNA–protein interactions | epitranscriptomics | N6-methyladenosine | pseudouridine
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2018, Volume 97, Issue 2, pp. 313 - 325.e6
N6-methyladenosine (m6A) affects multiple aspects of mRNA metabolism and regulates developmental transitions by promoting mRNA decay. Little is known about the... 
CNS axon regeneration | YTHDF1 | Mettl14 | epitranscriptomics | PNS axon regeneration | DRG | protein synthesis | mRNA methylation | RGC | Translation | Neurons | mRNA turnover | Genes | Methyltransferase | Central nervous system | Retina | Nervous system | Protein biosynthesis | Roles | Metabolism | Ribonucleic acid--RNA | Neurogenesis | Proteins | Regeneration | Dorsal root ganglia | Stem cells | DNA methylation | Epigenetics | Sciatic nerve
Journal Article
Biochimica et biophysica acta. Gene regulatory mechanisms, ISSN 1874-9399, 2019, Volume 1862, Issue 3, pp. 370 - 381
N6-methyladenosine (m6A) is a highly pervasive and dynamic modification found on eukaryotic RNA. Despite the failure to comprehend the true regulatory... 
RNA modification | m6A | Epitranscriptomics | Post-transcriptional gene regulation | Viral replication | Virus-host interactions
Journal Article
Molecular cell, ISSN 1097-2765, 2017, Volume 68, Issue 5, pp. 993 - 1005.e9
Gene expression can be post-transcriptionally regulated via dynamic and reversible RNA modifications. N1-methyladenosine (m1A) is a recently identified mRNA... 
RNA modification | N1-methyladenosine | epitranscriptomics | RNA epigenetics | mitochondria | base-resolution | translation regulation | m1A
Journal Article
Frontiers in oncology, ISSN 2234-943X, 2019, Volume 9
Recent studies have uncovered an important role for RNA modifications in gene expression regulation, which led to the birth of the epitranscriptomics field. It... 
AML | METTL14 | Epitranscriptomics | RNA | Leukemia | METTL3 | M6A | Post-translational modification | Molecular targeted therapy | Messenger RNA | Oncology, Experimental | Research | Health aspects | Cancer | leukemia | m6A
Journal Article
Circulation Research, ISSN 0009-7330, 02/2018, Volume 122, Issue 3, pp. 399 - 401
Increasing usage of next generation sequencing (NGS) technology will illuminate the extent of RNA modifications, which may affect various pathophysiological... 
Inosine | Adenosine | RNA editing | Mice | Gene expression | RNA modification | epitranscriptomics | Gene regulation | Information technology | gene expression | Functional genomics
Journal Article
RNA biology, ISSN 1555-8584, 2018, Volume 15, Issue 6, pp. 1 - 3
Journal Article